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17 Cards in this Set

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What is an Action Potential?

A short-term change in the electrical potential on the surface of an axon due to a stimuli: changes from -65megavolts to +40 megavolts inside the membrane.

On what space does an action potential move once its been created?

Rapidly

Stage 1 of the passage of an action potential on unmyelinated axon.

At resting potential the conc of sodium ions outside the axon is high compared to the inside, the potassium ions are high inside the membrane compared to the outside. There is more positive ions outside the membrane than there is inside. The axon membrane is POLARISED.

What does it mean when is the membrane polarised?


When there is more positive ions on the outside compared to the inside of the axon membrane.

Stage 2 of the passage of an action potential on unmyelinated axon.

A stimulus causes a sudden influx of sodium ions. This causes reversal charge on the axon membrane (-65 megavolts to +40 megavolts). This is the action potential and the membrane is depolarised!

What is Depolarisation?

When the outside is more negative relative to the inside of the axon membrane.

Stage 3 of the passage of an action potential on unmyelinated axon.

The localised electrical circuits established by the influx of sodium ions causes the sodium voltage gated channels to open a little further.This causes depolarisation. Behind this new region of depolarisation , the sodium voltage-gated channels close and the potassium ones open. Pottasium ions begin to leave the axon along their electrochemical gradient.

Stage 4 of the passage of an action potential on unmyelinated axon.

the action potential is spread across the axon the same way further along the axon. The movement of potassium ions out of the membrane has continued to the extent that the axon membrane behind the action potential has returned to its original charged state (- 65 megavolts inside and positive outside) it has been repolarised.

What is repolarisation?

When the axon membrane has returned to its original charges after being depolarised by the reversal of charges caused by a stimuli.

Stage 5 of the passage of an action potential on unmyelinated axon.

The repolarisation of the axon membrane allows sodium ions to be actively transported out , once again returning the axon to its resting potential in readiness for a new stimulus.

What is a myelinated Axon?

There is a fatty sheath of myelin around the axon.

What's the purpose of this sheath of myelin?


To act as an electrical insulator preventing potentials from forming.

What are the gaps between the Schwann cells that surround the axon membrane?

Nodes of Ranvier

How can an action potential pass along the axon membrane when its fully covered by sheath of myelin?

It can jump from gap to gap ( these points are called Nodes of Ranvier). this is called Salutatory conduction.

What is meant by the tern "Salutatory conduction" ?

When the Action Potential jumps from node Ranvier to node Ranvier because these are the only gaps where there is no sheath of myelin surrounding the axon preventing it from potentials.

Instead of walking across the axon membrane if I jump how will this be to my advantage? ref to the Action potential.

YOU will be able to move across faster. So the action potential is able to move across the axon membrane faster when it jumps from node to node.

The action potential moves faster on a unmyelinated axon.true of false?

False the action potential moves faster on a myelinated axon because instead of moving across through every gate of the unmyelinated axon because its got no sheath to hinder potential because its an electrical insulator. It can jump from nodes of Ranvier to node of Ranvier because these are gaps were there is no sheath.