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9 Cards in this Set

  • Front
  • Back
The structure of DNA must allow...?
-Replication
-Storage and expression of -information
-Recombination
-Mutation and repair
-Evolution
What did Phoebus Levene discover
-ribose
-deoxyribose
-defined a nucleotide as a phosphate - sugar - base
-he did not believe that DNA held the genetic information b.c it was two simple
Chargaff’s Rule?
-A=T and G=C
-but A, C, G, and T are not equimolar
Rosalind Franklin role?
-X-ray diffraction images of DNA
- Her data helped created Crick and Watson's structure of DNA
Basic structure of DNA?
-right handed helix
-major and minor grooves
-10 bases per turn
-20 A in diameter
-The hydrogen bonds form only
between A and T or G and C
-The phosphodiester backbones are antiparallel
The backbones are polymers of nucleotides ?
5' --> 3'
Different ways to name nucleotides
N: base, deoxynucleoside, nucleotide

A: adenine, deoxyadenosine, deoxyadenosine 5’-triphosphate

C: cytosine, deoxycytidine, deoxycytidien 5’-triphosphate
G: guanine, deoxyguanosine, deoxyguanosine 5’-triphosphate

T: thymine, deoxythymidine, deoxythymidine 5’-triphosphate

U: uracil, uridine, uridine 5’-triphosphate
What bases are a pyrimidine and purine.
What is A, B, and Z DNA?
-A-DNA happens in dehydrated environments, has a wider spiral and is shorter
-B-DNA happens in regular conditions, 10 base per turn
-Z-DNA can can form when the DNA is all …GCGCGCGC