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48 Cards in this Set
- Front
- Back
Each cell has a unique pattern of gene expression to produce the unique set of ____ and specialized_____ that defines its function in the body.
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Proteins
RNA Molecules |
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Select proteins must interact effectively with the DNA regulatory sequences in order to regulate ____, and thus, gene expressions effectively.
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Transcription
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Which model describes the regulation of transcription in prokaryotes?
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Lactose (LAC) Operon Model
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The ____ and _____ of a gene is a gene expression
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Regulated Activation (Turn-On)
Deactivation (Turn-off) |
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When will you be able to know when the gene is activated?
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When the cell needs the product it encodes
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When will you be able to know when the gene is deactivated?
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When the cell does not need the product it encodes
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The precisely regulated activation and deactivation of a gene is called _____.
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Gene expression
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Each cell type makes a unique set of ___ and ____ in order to perform its function in the body.
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Proteins and RNA molecules
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Each of our cell types has a unique pattern of _____.
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Gene Expression
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What genes must be expressed in the RED blood cell in order for the red blood cell to perform its function in the body?
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All genes that code for protein are found in the red blood cell
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What genes must be expressed in the WHITE blood cell in order for the white blood cell to perform its function in the body?
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All the genes necessary needed in red blood cells to maintain energy
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______ can influence the pattern of gene expression within a single cell.
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Environmental changes
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Each cell type expresses a unique pattern of ____ at a stage of its development
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Genes
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The ____ is a group of genes clustered on the bacterial chromosome that regulates a specific metabolic process
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Operon
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All genes in an operon are _____ or _____ as a single unit
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Expressed or repressed
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A _______ is sufficient to turn-on or turn-off the operon.
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Single Molecular Switch
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The _____ is an energy-efficient method to organize gene expression
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Operon
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All the genes in an operon are ____ or _____ by a single unit by a single molecular switch.
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Expressed or repressed
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The LAC operon allows E.Coli to catabolize _____ to make ATP.
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Lactose
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Each gene in the LAC Operon encodes a ____ necessary for lactose use.
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Protein
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The LAC Operon is _____ WITH lactose in the cell and ____ WITHOUT lactose
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Expressed
Repressed |
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What is an operon on the bacterial chromosome?
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A group of genes clustered together in this chromosome
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All of the genes of an operon typically contribute to a ____ Metabolic Process
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Single
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What are the benefits of arranging multiple genes in an operon on the bacterial chromosome?
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Can be turned on or off simultaneously, easier to regulate.
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The LAC Operon allows the bacterium E.Coli to catabolize ______ to make ATP.
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Lactose
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Where does E.Coli live?
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Human Colon
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LAC Operon genes enable E.Coli to use Lactose as a source of ____ to make ATP.
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Energy
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______ transports lactose into the cell.
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Permease
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Galactose is converted to glucose that enters ____.
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Glycolysis
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Beta-Galactosidase splits lactose into ____ and _____
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Galactose
Glucose |
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Glucose immediately enters ___ to make ATP.
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Glycolysis
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Degrades Lactose into 2 disaccarides: ______ and _____.
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Galactose and Glucose
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_____ splits lactose and glucose into 2
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Beta-Galactoside
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Where does E.Coli live symbiotically within our bodies?
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Colon or large intestine
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Why would E.Coli living in the large intestine of mammals have evolved the ability to catabolize lactose?
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Because mammals produce and drink milk. Bacteria with lactose had a big advantage, nutrition is mother's milk.
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How do the LAC Z and LAC Y genes contribute to E.Coli Catabolism?
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Breaks down Lactose into Galactose and Glucose to make atp
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The _____ and _____ are DNA regulatory sequences that contribute to the precise regulation of LAC Operon Expression.
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Promoter and Operator
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The repressor protein coded by the LAC I Gene binds to the ______ to regulate LAC Operon expression.
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Operator
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Why is the LAC operon expressed without lactose?
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Because the bacterium does not need to catabolize lactose
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With the absence of Lactose, the E.Coli would _______ energy.
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Waste
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Why does lactose induce LAC operon expression?
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Because the bacterium needs the proteins to catabolize lactose
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Why does glucose represses the lac operon expression?
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Because E.Coli does not need to catabolize lactose to produce more glucose when it already has a supply of glucose.
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The ________ stimulates RNA Polymerase activity to increase transcription in the absense of glucose
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Catabolite Activator Protein
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What determines if LAC Operon Expression will occur?
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Lactose
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_____ regulates the expression rate .
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Glucose
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When a mutation prevents the lac repressor protein from binding to the operator, how will lac operon expression be affected?
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The lac operon will not have to worry about an active repressor binding to the operator. There would be no repressor to inhibit the lac operon from being turned on.
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When a mutation prevents the lac repressor protein from releasing from the operator, how will lac operon expression be affected?
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It will be continuously inhibited because regardless of the presence of lactose, the operator will continuously be repressed because of the active repressor protein.
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What is gene expression?
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Precisely regulated activation and deactivation of a gene.
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