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48 Cards in this Set

  • Front
  • Back
Each cell has a unique pattern of gene expression to produce the unique set of ____ and specialized_____ that defines its function in the body.
Proteins
RNA Molecules
Select proteins must interact effectively with the DNA regulatory sequences in order to regulate ____, and thus, gene expressions effectively.
Transcription
Which model describes the regulation of transcription in prokaryotes?
Lactose (LAC) Operon Model
The ____ and _____ of a gene is a gene expression
Regulated Activation (Turn-On)
Deactivation (Turn-off)
When will you be able to know when the gene is activated?
When the cell needs the product it encodes
When will you be able to know when the gene is deactivated?
When the cell does not need the product it encodes
The precisely regulated activation and deactivation of a gene is called _____.
Gene expression
Each cell type makes a unique set of ___ and ____ in order to perform its function in the body.
Proteins and RNA molecules
Each of our cell types has a unique pattern of _____.
Gene Expression
What genes must be expressed in the RED blood cell in order for the red blood cell to perform its function in the body?
All genes that code for protein are found in the red blood cell
What genes must be expressed in the WHITE blood cell in order for the white blood cell to perform its function in the body?
All the genes necessary needed in red blood cells to maintain energy
______ can influence the pattern of gene expression within a single cell.
Environmental changes
Each cell type expresses a unique pattern of ____ at a stage of its development
Genes
The ____ is a group of genes clustered on the bacterial chromosome that regulates a specific metabolic process
Operon
All genes in an operon are _____ or _____ as a single unit
Expressed or repressed
A _______ is sufficient to turn-on or turn-off the operon.
Single Molecular Switch
The _____ is an energy-efficient method to organize gene expression
Operon
All the genes in an operon are ____ or _____ by a single unit by a single molecular switch.
Expressed or repressed
The LAC operon allows E.Coli to catabolize _____ to make ATP.
Lactose
Each gene in the LAC Operon encodes a ____ necessary for lactose use.
Protein
The LAC Operon is _____ WITH lactose in the cell and ____ WITHOUT lactose
Expressed
Repressed
What is an operon on the bacterial chromosome?
A group of genes clustered together in this chromosome
All of the genes of an operon typically contribute to a ____ Metabolic Process
Single
What are the benefits of arranging multiple genes in an operon on the bacterial chromosome?
Can be turned on or off simultaneously, easier to regulate.
The LAC Operon allows the bacterium E.Coli to catabolize ______ to make ATP.
Lactose
Where does E.Coli live?
Human Colon
LAC Operon genes enable E.Coli to use Lactose as a source of ____ to make ATP.
Energy
______ transports lactose into the cell.
Permease
Galactose is converted to glucose that enters ____.
Glycolysis
Beta-Galactosidase splits lactose into ____ and _____
Galactose
Glucose
Glucose immediately enters ___ to make ATP.
Glycolysis
Degrades Lactose into 2 disaccarides: ______ and _____.
Galactose and Glucose
_____ splits lactose and glucose into 2
Beta-Galactoside
Where does E.Coli live symbiotically within our bodies?
Colon or large intestine
Why would E.Coli living in the large intestine of mammals have evolved the ability to catabolize lactose?
Because mammals produce and drink milk. Bacteria with lactose had a big advantage, nutrition is mother's milk.
How do the LAC Z and LAC Y genes contribute to E.Coli Catabolism?
Breaks down Lactose into Galactose and Glucose to make atp
The _____ and _____ are DNA regulatory sequences that contribute to the precise regulation of LAC Operon Expression.
Promoter and Operator
The repressor protein coded by the LAC I Gene binds to the ______ to regulate LAC Operon expression.
Operator
Why is the LAC operon expressed without lactose?
Because the bacterium does not need to catabolize lactose
With the absence of Lactose, the E.Coli would _______ energy.
Waste
Why does lactose induce LAC operon expression?
Because the bacterium needs the proteins to catabolize lactose
Why does glucose represses the lac operon expression?
Because E.Coli does not need to catabolize lactose to produce more glucose when it already has a supply of glucose.
The ________ stimulates RNA Polymerase activity to increase transcription in the absense of glucose
Catabolite Activator Protein
What determines if LAC Operon Expression will occur?
Lactose
_____ regulates the expression rate .
Glucose
When a mutation prevents the lac repressor protein from binding to the operator, how will lac operon expression be affected?
The lac operon will not have to worry about an active repressor binding to the operator. There would be no repressor to inhibit the lac operon from being turned on.
When a mutation prevents the lac repressor protein from releasing from the operator, how will lac operon expression be affected?
It will be continuously inhibited because regardless of the presence of lactose, the operator will continuously be repressed because of the active repressor protein.
What is gene expression?
Precisely regulated activation and deactivation of a gene.