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68 Cards in this Set

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Cell History - Who was involved and what did they do?

1660 - Leeuwenhoek - microscope


1665 - Hooke - viewed cork cells


1831 - Brown - nucleus


1838 - Schleider & Schwan - cell theory


1846 - Purkenjie & Mohl - protoplasm


1888 - Schneider - chromosomes


1898 - Golgi - golgi bodies


1931 - Knoll & Ruska - electron microscope

Cell theory

-Cells are the basic unit of structure in all living organisms (All living things are made up of cells)


-Cells are the basic unit of function in all living organisms (Life occurs because of chemical reactions in cells)


-All cells come from pre-existing cells

Compare and contrast eukaryotic and prokaryotic cells

-Eukaryotes - contain a membrane bound nucleus (ex: plant cells, animal cells)


-Prokaryotes - do not have a "true" nucleus (ex: bacteria)

Cell (plasma) membrane

controls movement of materials in and out of the cell

Cell wall

protects and supports plant cells (plant cells only)

Chloroplast

responsible for photosynthesis (plant cells only)

Cytoplasm

all material in the cell except the nucleus (main functioning area of the cell)

Endoplasmic reticulum

responsible for the making and transportation of cell products

Golgi apparatus (body)

storing, packing, and transporting materials

Lysosome

contains enzymes for digesting food or cell parts (animal cells only)

Mitochondrion

energy producers

Nucleus

general control area of the cell

Nucleolus

makes ribosomes and helps with protein synthesis

Nuclear membrane (envelope)

controls movement of materials in and out of the nucleus

Ribosomes

make protein

Vacuole

storage for food, water, waste, etc. (large ones in plant cells only)

Centrosome

helps with cell division (animal cells only)

Chromatin (DNA, chromosomes)

threadlike structures that contain all the information about the cell (DNA)

Flagellum

helps move the cell

What must all cells and living organisms do?

-absorb nutrients to survive and grow


-convert nutrients to usable energy


-be able to reproduce


-eliminate wastes

Unicellular organisms

-only one cell


-must perform all cell functions

Multicellular organisms

-multiple cells


-often have specialized cells that carry out certain functions


-these cells cooperate with each other to carry on life

List differences between plant and animal cells

-Only plant cells contain a cell wall, chloroplast, and large vacuoles


-Only animal cells contain lysosomes and centrosomes

Passive transport

-passive transport is the movement of materials across the cell membrane that requires no energy from the cell


-particles are generally smaller and uncharged (neutral) and move from high to low transportation

Active transport

-the transport of molecules in and out of the cell that requires energy from the cell


-usually occurs when moving particles from an area of low concentration to an area of higher concentration


-larger charged particles (ions) are moved


-in this case a transport protein spins and takes substances across the membrane

What are 3 molecules that can diffuse across a bilipid membrane?

H2O, CO2, O2

Simple diffusion

movement of materials from an area of higher concentration to an area of lower concentration (H2O, CO2, and O2 can diffuse through cell membrane between the fat molecules or through a non-specific protein channel)

Facilitated diffusion

particles that are too big to go through the membrane are moved through a specific protein "carrier molecule" in the cell membrane

Osmosis

-diffusion of water across the cell membrane


-if some particles (ex: ions) cannot pass through the cell membrane, then water may pass in or out of the cell to balance the concentrations

Endocytosis

movement of large amounts of materials into a cell (usually nutrients) by the membrane wrapping around the material and "pinching off"


-Pinocytosis - tiny chunks (liquid)


-Phagocytosis - larger chunks (food)

Exocytosis

The movement of large amounts of materials (usually wastes) out of the cell by a vacuole moving to the cell membrane (opposite of endocytosis)

Cyclosis (cytoplasmic streaming)

-the passive movement of the cytoplasm and its contents (various organelles) around the cell


-aids with diffusion of particles within the cell

Tonicity

the concentration of ions (ex: salt) inside a cell, relative to the concentration of ions outside the cell in the surrounding solution

Hypertonic solution

-a cell is placed in a salt solution stronger in concentration than itself


-cell shrivels

Hypotonic solution

-a cell is placed in a salt solution weaker in concentration than itself


-cell expands

Isotonic solution

-a cell is placed in a salt solution equal in concentration to itself


-cell stays the same size

Plasmolysis

what happens to a plant cell when placed in a hypertonic solution (shrivels)

What are the stages of mitosis in order?

-Interphase


-Prophase


-Prometaphase


-Metaphase


-Anaphase


-Telophase


-Cytokinesis

What are the 3 stages of interphase?

-G1 - cell growth


-S - DNA is replicated


-G2 - cell grows again and prepares for cell division

List and explain the two subdivisions of cell division

-Mitosis - nuclear division


-Cytokinesis - actual division of the cytoplasm and pinching of the cell membrane into two cells

Interphase

stage before cell division where chromatin (DNA) replicate

Prophase

chromatin condense into chromosomes

Prometaphase

nuclear membrane breaks down and the spindle fibres attach to the chromosomes

Metaphase

chromosomes align along the middle of the cell (equatorial plate)

Anaphase

sister chromatids separate and are pulled apart to opposite poles

Telophase

chromosomes reach the poles and two new nuclei are formed, completing mitosis

Cytokinesis

the cytoplasm and its contents (organelles) are divided in half as the cell membrane pinches together (cleavage furrowing) resulting in two cells

Cell differentiation

-when a cell becomes specialized in order to perform a specific function


-becomes one of the 210 cell types in the body (skin cell, muscle cell, blood cell, etc)

Clone

an exact genetic copy of an organism

Explain the history of cloning in plants

-plants can clone themselves naturally


-humans can clone plants

What was the first animal cloned?

frog

How were the first mammals cloned?

the use of embryos

Enucleation

removing nucleus from an egg

Nuclear transfer

moving nucleus from from one cell into a enucleated egg

How did they prove Dolly was a clone?

genetic testing

Why do humans want to clone?

-reproductive purposes


-medical reasons

What are nature-made clones?

identical twins

Stem cells

special cells that can


-divide for indefinite periods


-turn into any of the 210 cells

What are the 3 potential applications of stem cells?

-drug testing


-genetic experiments


-cells and/or organ production

Pluripotent (embryonic) stem cells

-easy to work with


-able to replicate

How are stem cells obtained? (4)

-from embryos from IVF (in vitro fertilization)


-from fetal tissue obtained from terminated pregnancies


-somatic cell nuclear transfer (SCNT)


-adult stem cells

How are embryonic stem cells obtained?

from the inner cell mass of human embros

How are fetal stem cells obtained?

from the cell mass of human fetal tissue

Explain somatic cell nuclear transfer

-using cloning techniques


-using enucleation and nuclear transfer to create an inner cell mass containing stem cells

Cancer

uncontrolled cell division

Tumor

lumps or masses of tissue formed by uncontrollable cell division

Metastize

when a tumor successfully spreads to other parts of the body and grows, invading and destroying other healthy tissues

Describe the 4 typical gene mutations that can often lead to cancer

-Oncogenes - tell cells when to divide (ON SWITCH)


-Tumor Supressor Genes - tell cells when not to divide (OFF SWITCH)


-Suicide Genes - tell the cell to kill itself


-DNA Repair Genes - instruct a cell to repair damaged DNA