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25 Cards in this Set

  • Front
  • Back
Metabolism
-All chemical reactions in organisms
-conversion of organic substances
-employs enzymes (biocatalysts)
Energy
-equivalent to work
-measured in Joules
-includes heat, mechanical work, electricity, light
-interchangeable
1st Law of Thermodynamics
The total amount of energy is stable.
2nd Law of Thermodynamics
Orderliness spontaneously decreases (and entropy increases).

Highly ordered organisms have low entropy.
3rd Law of Thermodynamics
Organisms need to invest energy to maintain high levels of order
4th Law of Thermodynamics
Organic compounds are energy rich, they store energy
5th Law of Thermodynamics
Autotrophs convert light into chemical energy. Heterotrophs take up organic compounds.
Catabolism
Energy stored in organic compounds can be retrieved by breaking them down into low energy compounds
Oxidation
Fire is oxidation.

Glucose+Oxygen -> Carbon Dioxide and Water

Biological Oxidation: Respiration. Energy is saved as ATP (Adenosine Triphosphate)
Anabolism
The synthesis of high energy organic compounds. These reactions require energy.

Example: synthesis of sugars from carbon dioxide and water during Photosynthesis
Carbohydrates
-high energy organic compounds
-often ratio C H2 O
-initially formed in photosynthesis
-Sugars: mono- and disaccharides
-polysaccharides
Lipids and Fats
-high energy organic compounds
-chemically diverse
-hydrophobic
-triglycerides
-phospholipids
-steroids
Triglycerides
3 fatty acid molecules attached to a glycerol
Phospholipids
2 fatty acid molecules attached to a glycerol plus a phosphate group
Steroids
-Interlocked molecule rings
-cholesterol, a component of biomembranes
-testosterone, produced in testes and ovaries
-estrogen
Respiration
-biological oxidation
-controlled by enzymes
-catabolic process
-energy is harvested as ATP
ATP - Adenosine Triphosphate
-Assembled by energy-yielding metabolic pathways
-"Used" to drive energy-consuming pathways
-a nucleotide
Other nucleotide-based Compounds shuttle hydrogen
-hydrogen atoms are shuttled from one place to another and from one compound to another
-change between oxidized and reduced state
-play a central role in metabolism
How do organisms use energy?
Cellular respiration:
-metabolic pathways in which cells harvest the energy from the metabolism of food molecules
-occurs in 3 stages: glycolysis, krebs cycle, and electron transport chain
Glycolysis
-occurs in the cytoplasm
-net reaction
-two results: generation of high-energy molecules (ATP, NADH); production of pyruvate that enters Krebs cycle
When Oxygen is Limited...
Two problems with anaerobic cellular respiration:
-2 ATPs / glucose molecule will not sustain activity for long periods
-in the absence of oxygen, glycolysis converts all of the limited NAD+ to NADH (and with no more NAD+ glycolysis ceases)
Fermentation
-occurs in the absence of oxygen
-results in incomplete catabolism
-lactic acid or ethanol
-NAD+ is replenished to sustain Glycolysis
With Oxygen Present...
Transitional step before Krebs cycle:
-Accomplishes 3 things:
1) Hydrogen atoms removed from pyruvic acid and added to NAD+ to make NADH
2) Carbon atom is removed from pyruvic acid and lost as CO2
3) resulting two-carbon molecule is attached to carrier molecule (coenzyme A) forming acetyl-CoA

-performed by large enzyme in the mitochondria
Citric acid cycle - Definition
-occurs in the matrix (inner compartment) of the mitochondria
-a cyclic series of enzymatically controlled reactions
Citric acid cycle - Process
1. Pyruvate (product of glycolysis) is imported from the cytoplasm.
2. Pyruvate (3 carbon compound) is converted into a 2 carbon compound that is linked to a carrier molecule: acetyl-CoA
3. 1st reaction: citric acid (6C) is formed from oxalacetate (4C) and the acetyl group (2C) of acetyl-CoA
--->two carbon atoms are lost as CO2
4. Oxalacetate is regenerated
5. Main outcome (in addition to ATP) is energy-rich NADH, which feeds into electron transport chain