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53 Cards in this Set

  • Front
  • Back
What is an organic molecule?
1. formed by living organisms
2. have carbond based core with attached atoms called functional groups
What is a functional group?
1. Groups of atoms attached to the core of an organic molecule.
2. Functional group confers specific chemical properties on the organic molecule.
What are the 5 Functional Groups?
1. Hydroxyl
2. Carbonyl
3. Carboxyl
4. Amino
5. Phosphate
Where are the 5 functional groups found?
1. Hydroxyl- Carbohydrates
2. Carbonyl- Lipids
3. Carboxyl- Proteins
4. Amino- Proteins
5. Phosphate- DNA, ATP
What are macromolecules know as and why?
The building materials of the body because they can be very large.
What are the 4 types of macromolecules?
1. Proteins
2. Nucleic Acids
3. Carbohydrates
4. Lipids
What are macromolecules assembled from?
Monomers
What is a monomer?
Simple molecules that can join together to form polymers.
What is a polymer?
Assembled chain of monomers.
A single cell is composed of how many atoms?
Trillions
What is dehydration synthesis?
1. how polymers are assembled.
2. Covalent bond formed when (OH) is removed from one subunit and (H) from another. (H2O is being removed)
Pg. 51
What is Hydrolysis?
Disassembling polymers by adding H2O to break the covalent bond.
What are proteins?
1. Complex macromolecules that are polymers made of amino acids. (Polypeptide)
What is an amino acid?
Amino acids are small molecules with a simple basic structure, a carbon atom to which three groups are added:
an amino group (—NH2)
a carboxyl group (—COOH)
a functional group (R)
* func. groups gives amino acids their chemical identity
What kind of bond links 2 amino acids to form polymers?
peptide bond
What is a polypeptide?
long chain of amino acids linked by peptide bonds.
How many different types of amino acids are there?
20
What are 2 important things about the proteins structure?
1. sequence of the amino acids affects how the protein folds together
2. the way that a polypeptide folds to form the protein determines the protein’s function
Are some proteins comprised of more than 1 polypeptide?
Yes
What are the 4 general levels of protein structure?
1. Primary
2. Secondary
3. Tertiary
4. Quaternary
What is primary structure of proteins?
sequence of amino acids in polypeptide chain determines ALL other levels
What is secondary structure of proteins?
Forms because regions of the polypeptide that are nonpolar are forced together; hydrogen bonds can form between different parts of the chain.
-The folded structure may resemble coils, helices, or sheets
What is tertiary structure of proteins?
Final 3-D shape of the protein.

Twists and folds that lead to this shape are the result of polarity differences in regions of the polypeptide.
What is quaternary structure of proteins?
Spatial arrangement of proteins comprised of more than one polypeptide chain.

pg 54
The shape of a protein can affect its __________.
Function
What does it mean for a protein to denature?
Protein unfolding (hydrogen bonding affected) due to:
Temperature or lower pH levels
What are some example of denaturing of protein?
Frying an egg or brain damage by increased temperature.
Is denatured protein active or inactive?
Inactive
What is the shape and function of an enzymes?
1. Globular proteins, 3-D shape and fit precisely with another chemical.
2. causes the chemical they fit with to have a reaction which is called catalysis.
What is catalysis?
When an enzyme causes another chemical to have a chemical reaction
What are chaperone proteins and what do they do?
Special proteins which help other proteins with the folding process. Chaperone proteins can correct misfolded protein.
Ex. of chaperone protein looks like a washing machine.
What can defective chaperone proteins play a role in?
Genetic disorders like Cystic fibrosis and Alzheimer's
What are nucleic acids?
1. Type of macromolecule.
2. Very long polymer that stores info
3. Comprised of nucleotides
What are nucleotides?
-Monomers (single unit of nucleic acid) composed of 3 parts:
1. a five carbon sugar
2. a phosphate group
3. an organic nitrogen-containing base
What are the 3 parts of a nucleotide?
1. a five-carbon sugar
2. a phosphate group
3. an organic nitrogen-containing base
How many different types of nucleotides are there?
5
What are the 5 nucleotide bases?
1. Adenine
2. Cytosine
3. Guanine
4. Thymine (DNA only)
5. Uracil (RNA only)
What are the 2 types of nucleic acids?
DNA- Deoxyribonucleic acid
RNA- Ribonucleic Acid
What are the differences between RNA and DNA?
RNA
1. uses uracil instead of thymine
2. comprised of just one strand
3. has a ribose sugar
What is the structure of DNA?
Double Helix
What does Adenine pair with?
Thymine
What does Cystosine pair with?
Guanine
Why is the structure of DNA a double helix?
1. because only 2 base pairs possible (A/T or C/G)} 2.aligned by hydrogen bonds holding base pairs together
3. sugar-phosphate backbone gives support
How does the structure of DNA help it to function?
hydrogen bonds of the base pairs can be broken to unzip the DNA so that info can be copied.
-each strand of DNA is a mirror image so that the DNA contains two copies of the information
-having two copies means that the information can be accurately copied and passed to the next generation
Why doesn't Adenine pair with Guanine?
Polarity
Why doesn't Adenine pair with Cytosine?
size
What are carbohydrates?
Macromolecules that make up the structural framework of cells and play a critical role in energy storage.
What elements does a carbohydrate contain?
C, H, and O in 1:2:1 ratio
What are the sizes of carbohydrates?
1. Simple- 1 or 2 monomers
2. Complex- long polymers
What is a simple carbohydrate with only 1 monomer called? Give an ex.
monosaccharides

ex. glucose (C6:H12:O6)
What is a simple carbohydrate with 2 monosaccharides? Give an ex.
Disaccharides

Ex. sucrose which is glucose+fructose
What are complex carbs?
long polymer chains called polysaccharides
Complex carbs contain what which make them good for storing energy?
many C-H bonds which are broken by organisms to obtain energy