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12 Cards in this Set
- Front
- Back
penetration of drugs into central nervous system |
drug must pass through blood brain barrier to affect the brain |
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ways drugs can affect the brain |
1. bind to a receptor 2. influencing synthesis, transport, and releae of a neurotransmitter 3. influencing deactivation of a neurotransmitter (eg reuptake of neurotransmitter |
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drug metabolism |
drugs made into non active forms by enzymes 1. usually enzymes produced by liver 2. usually now can't pass through blood brain barrier 3. some passed by urine, breath, sweat, feces, mothers milk--used for drug tests |
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drug tolerance |
1. decreased sensitivity to a drug that develops as a result of exposure to the drug 2. a shift in dose response curve |
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tests of drug tolerance |
1. same amount of drug has less effect with repeated use 2. takes more of the same drug to get same effect with repeated use |
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dose response curve |
graph of size of effect of drug with different doses. has many uses |
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tobacco |
1. leading cause of preventable deaths worldwide 2. nicotine 3. tar |
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nicotine |
major psychactive ingredient in tobacco. affects nicotinic cholinergic (acetylcholine) receptors of the brain |
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tar |
collective term for other chemicals in tobacco |
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tobacco addiction |
show tolerance 1. first cigarette often unpleasant experience |
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unpleasant symptoms of first cigarette |
1. coughing 2. nausea 3. sweating 4. dizziness 5. cramps 6. flushing |
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cigarette smokers symptoms |
1. report more relaxed, alert, less hungry after smoking 2. craving for cigarette |