Biological Factors Affecting The Action Of Drugs.

Front 1

percentage of the drug dosage that is absorbed

Back 1

bioavailability

Front 2

entrance of a drug into the bloodstream from its site of administration

Back 2

drug absorption

Front 3

condition of reliance on the use of a particular drug, characteerized as physical and/or psyc\hological dependence.

Back 3

drug dependence

Front 4

group of enzymes located primarily in the liver that function to metabolize (biotransformation) drugs.

Back 4

drug microsomal metabolizing system (DMMS)

Front 5

decreased drug effect occuring after repeated drug administration.

Back 5

drug tolerance

Front 6

increase in the amount of drug-metabolizing enzymes after repeated administration of certain drugs.

Back 6

enzyme induction

Front 7

inhibition of drug-metabolizing enzymes by certain drugs

Back 7

enzyme inhibition

Front 8

drug metabolism that occurs following oral absorption from the GI tract.

Back 8

firt-pass metabolism

Front 9

time required for the body to rid itself of half of the drug dosage that was absorbed (percent bioavailability)

Back 9

half-life

Front 10

difference in the effects of drugs and drug dosages from one person to another.

Back 10

individual variation

Front 11

route of drug administration; drug is injected into gluteal or deltoid muscles.

Back 11

intramuscular (IM) injection

Front 12

initial drug dose administered to rapidly achieve therapeutic drug concentrations.

Back 12

loading dose

Front 13

dose administered to maintain drug blood levels in the therapeutic range.

Back 13

maintenance dose

Front 14

rout of drug administration by way of the mouth through swallowing.

Back 14

oral administration

Front 15

rout of drug administration that does not involve the gastrointestinal (GI) tract.

Back 15

parenteral administration