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239 Cards in this Set

  • Front
  • Back
Neurons
information processing units
Glial cells
support and maintenance of the CNS
Types of glial cells
astrocytes
schwann cells
oligodendrocytes
ependymal cells
microglia
Meninges
surround, defend, and maintain tissue
Astrocytes
connects a blood source to a neuron for inport of nutrients and export of waste.

if the astrocytes shuts off the connection, the synapse collapses and that connection dies.
Cerebral spinal flud
buffered plasma; shock absorber and flushing device.
produced by the choroid plexus in the ventricles.
Schwann cells
PNS

one shwann cell per neuron
myelinates
Grey matter
neuron bodies in the cortex and spine.
Oligodendrocyte
CNS

many oligo's per neuron
myelination
White matter
myelin insulation of neuron processes. Fibrous processes running through the center of the brain connecting various parts.
Microglia
SOLDIERS

swarm to an area, engulf it, try to contain it so that it can be moved out of the system. can isolate and exportbut can't kill something.

crawl through the brain towards a chemical scent.
Myelin development

1-2 years
the first spurt is under the MOTOR CORTEX
Ependymal
form linings around things
Myelin development

3-5 years
the second is PARIETAL AND TEMPORAL LOBES
Myelin development

5-9 years
the third is diffuse, just the mass increases
Myelin development

10+ years
the fourth links the TEMPORAL with the FRONTAL
Myelin development

21 years of age
FRONTAL LOBE spurt and is associated with question seeking/heuristic thought processes.
Hindbrain
spine and medulla and cerebellum
Midbrain
thalamus, hypothalamus, and some limbic and basal ganglial structures
Forebrain
anteiror limbic system, basal ganglial, and cortical areas.
Positive feedback
one process stimulates another, this other stimulates another process that, in turn, stimulates the first.

this can set up a state of increasing tension or excitation that serves some limited, well controlled and regulated processes.

NORMALLY THIS MEANS DEATH
Negative feedback
activity in one system stmiulates activity in another that inhibits activity in the first.

All things biological rely on negative feedback to maintain function within homeostatic limits.
Functions of the CNS
maintaining homeostasis via feedback, equilibrium, sensing, and effecting.
Brainstem nuclei
source of many cranial nerves; neurotransmitter synthesis, motor reflex modulation.
Structures that make up the BRAINSTEM

and function of BRAINSTEM
medulla oblongata
pons
cerebellum
tegmentum
tectum

monitors automatic body functions; source of most neurotransmitters; route of motor output and sensory input; implementer of sleep/wake cycle; adjuster of state of arousal; reticular activating system.
Medulla
set of automatic, reflexive functions required for life.

damage here usually kills, or produces decerebrate rigidity
cerebellum
fine motor and postural motor control/modulation,
balance
integration of several senses into motor control.
Pons
arousal and attention
connects left and right cerebellar lobes; more cranial nerves. damage here causes decorticate rigidity.
tegmentum
arousal,
motor pathways,
circadian rhythms
tectum
sensory reflexes and initial processing,
circadian data processing
structures of the MIDBRAIN
thalamus
hypothalamus
basal ganglia
limbic system
thalamus
sensory relays and direction
initial information processing
all sensory input passes through this first before it gets relayed anywhere else
smell is the only sensory system that doesn't go through the thalamus; it goes through the limbic system
hypothalamus
ANS controllife function regulation
metabolism
endocrine control

control center of autonomic nervous system, seat of potentially first experience of hunger, thirst, fear.
considered the seat of primary motivators (hunger, thirst, sex, fear)
basal ganglia
fine motor control
muscle tone and preparedness
anticipation
some forms of learning
contributes to emotion preparedness, reaction, and response
limbic system
just beneath the cortex and surrounds the basal ganglia

memory
emotionality
sense of smell (smell is the only sense that doesn't pass through the thalamus first; it goes directly to the limbic system)
structures of the FOREBRAIN
cortex
cortex
the outermost layer of the brain (GREY MATTER)

higher informaiton processing
perception
awareness
learning
motor control
memory
self concept
planning
personality
Bio-Psycho-Social model
biological beings that think and feel in a social context
Nerves
bundles of axons in the PNS
Tracts
bundles of axons in the CNS
ascending to descending
Fasciculi
anterior-posterior tracts

front to back
commissures
large left-right tracts
internal capsule
subcortical white matter
Anterior

Rostral
toward the front
Posterior

Caudal
toward the rear
Lateral
toward the side
Medial
toward the midline
Sagittal
the plane of the midline
Horizontal
the plane from teh top
Frontal

Coronal
the plane from the face
Dendries
gather information
Soma
cell body

sums info up and processes it
axon
information transmitting process extending to other neurons
nodes of ranvier
the only place where actual potentials occur.
bouton
learning occurs (processing of neurontransmitter)
concentration gradient
low concentration on one side and a high contration on the other. this creates a potential.
electrostatic gradient
outside is positively charged, inside is negatively charged
Na+
outside to inside
K+
inside to outside; but it has a positive pull to stay inside the negative charge so it doesn't readily go out just because of the conc gradient.
Cl-
greater outside than inside

pressure from concentration gradient to enter cell counterbalanced by pressure from electrostatic gradient to leave the cell.
dendrytic potential
graded, non propogating (stay in dendrite)
axonal potential
all or nothing, self propogating

AXONAL = ACTION
when does the axon fire?
when stimulation reaches the excitation threshold via voltage-gated channels.
excititory potential
moving toward threshold
what changes about an axon
size and speed of axonal potential is constant, only the FREQUENCY changes
inhibitory potential
moving away from threshold
ephapsis
cell walls fuse together.

no delay, direction communication, this is for processing info super fast.

once they connect, they stay that way until the cells die.
temporal summation
a number of stimuli are received within a few ms
spatial summation
a number of stimuli are received at teh same time within a small section of the neuron.
relative refractory period
a few ms later the neuron has recovered sufficiently that it can be fired again but only at supernormal levels of stimulation
absolute refractory period
no matter how much stimulation, the axon will not fire again
speed of stimulus intensity
speed of stimulus intensity is encoded and determined by frequency of potentials not by change in potential size
neural conduction
electrical - ionic
synaptic activity
electrical - chemical
autoreceptors
detect nt's and reduce their release. they make the presynaptic membrance less sensitive to calcium which stops vesicle fusion and rupture into the cleft.
luria's functional units of brain organization
reflect systems of brain structures that underlie all forms of behavior, thought, and affect.
1st functional unit
AROUSAL

the sleep/waking processes and the processes determining level of arousal and attention
2nd functional unit
INPUT AND MEMORY
3rd functional unit
OUTPUT AND ACTION
facts about sleep
an active process of shutting down

not a uniform or consistent process
stage 1 of sleep
initial stage of sleep

from the time you decide to fall asleep to complete disconnection of sensory awareness.

represents hte brains decision to progress to deeper sleep.
stage 2 of sleep
represents the brains effort to establish and maintain sleep.

no mental activity, or incomplete, disjointed mentations
stage 3 of sleep
beginning of deep, slow wave sleep

no or minimal mental activity

physically restorative sleep
stage 4 of sleep
deep, slow wave sleep.

no mental activity

physically restorative sleep
REM
about 90 mins after sleep onset

complex, organized, emotionally laden mentations

biological necessity (REM rebound phenomena)

associated with memory processes

the prefrontal cortex is off during this state.

somatic musculature is turned off or actively inhibited so that dream experiences can't be acted on during sleep
REM rebound
occurs in the form of a mini withdrawal

usually associated with nightmares and restlessness.
Insomnias
onset, maintaince, early morning waking
Apneas
obstructive: something is in the way

central: stop trying to breathe, no respiratory effort (neurological)

mixed
cheyne-stokes
Barbitols and Phenobarbs
desensitizes the post synaptic membrane to ACH
Initial dose
can increase NEPI producing peripheral vasoconstriction/hypertension. this also contributes to disinhibition and a rush of euphoria.
large dose
slow cardiac and respiratory functions, produce peripheral vasodilation and lower blood pressure
produce euphoria and confusion.
produce sleep hangover
centrally
induce slow wave sleep and block REM.
Anesthesia
fast acting, short half lifers
small doses
activation from frontal leads; cloudoing of consciousness and euphoria
higher doses
EEG slowing, sleep is induced, but pain responses are still present
dangerous doses
EEG flattening, coma, no pain response is present, respiration may stop, death can occur.
homeostasis
keeping body functions and resources within a specific set of time
exteroceptors
eyes, ears, nose, etc

give first units of cognitive structure when combined with motor effect
interoceptors
organs, glands, muscles

gives most basic element of experience of self (what's going on with me, how do i feel)
need
specific deficit or imbalance
drive
the experience or sensation of a need, usually uncomfortable, act as motivators of action to reduce the state
motive
the goal to relieve the drive or fulfill the need
satiation
the experience of achievement of the motive, usually pleasant or comfortable
immediate biological drives
breathing, blood flow, thermoregulation, elimination, basic system integrity/function (pain, nausea, distress)
reflexive
automatic
lower brain structures
medullary
medullary
automatic, essential life forces not really motivators per se but can be a source of panic
ANS
largely independent and autonomous, and based on medullary processes and local (peripheral) controls/mechanisms/feedback.
basic motivators (less immediate biological need states)
need for food, water, procreative, and survival
2 components of ANS
parasymp NS
symp NS
parasympathetic NS
designed to store energy, heal injury, grow, reproduce
trophotopic: energy conserving
low energy output-digestive functions, specific, individualized system.
designed for sustained, restorative processes and energy retention/replenishment.
default system, active essential whenever the symp is not needed
sympathetic NS
designed to fight, flee, survive, expend energy
ergotropic: energy expending
high energy expenditure designed for brief, diffuse reaction to all oeprating systems
designed to enable peak performance; short bursts of activity at maximal levels to ensure survival
general adaptation syndrome
hans seyle
alarm, adaptation, exhaustion
appears to reflect experience, perception, and general state of fitness of organ systems (wear and tear)
multiple nuclei
each specialized in some form of homeostatic process.
when stimulated, create sensation of drive state.
when lesioned, often reduce, alter, or eliminate the drive state.
lateral hypothalamic nuclei (LH)
triggers consumatory behavior when blood sugar, protein, and fat are really low.
leasons to this nucleus cause teh organism to stop eating completely, no matter how long it's been or what you put in front of them.
ventral medial hypothalamus
satiety center; when sugar, protein, and fat have gone up, this tells you when you've had enough
anterior and preoptic nuclei
drinking, water, temperature regulation, sex
anterior pituitary
production of 7 important hormones
somatotropic
growth hormone, affects protein and lipid, carbohydrate, and calcium metabolism
ACTH
regulates activity of the adrenal glands
thyrotropin
regulates thyroxin secretion by the thryoid
hyperthyroidism
too much
myxedema
too little

behavioral slowing, depression like symptoms, faulty development of skin, teeth and cartilage, puffy, dry skin, cardiac anomalies, and menstrual irregularities
prolactin
promotes growth of breast tissue and maintains lactation
secretion of progesterone
FSH and LH
regulate ovary and testicle development
estrogen secretion in women
spermatogenesis in men
MSH
regulation of pigmenting cells in the skin
Posterior pituitary
produces 2 hormones
Oxytocin
stimulates uterine contractions in pregnancy, reduces bleeding, and releases milk into ducts.
vasopressin
helps constrict smaller arteries to increase blood pressure, reduces water loss through kidneys, and stimulates digestive smooth muscle
thorasal lambar
sympathetic exit

all organs get the message at once
cranial sacral
parasympathetic exit
cingulate gyrus
limbix cortex
realization of emotional experience
associated with numerous aspects of self
involved in both input and output of data
luria's 2nd functional unit
acquisition, processing, and storing of information
perception
learned through experience with sensations and teh consequences of these sensations (motor activity)
perceptions guide volitional action and further cognitive development they then modify attention and the detection of new sensations
2 way street of information processing
1. perceptions guide action and further cognitive development. perceptions then modify attention and the detection of new sensations
2. new sensations can challenge the existing cognition.
transduction
the conversion of physical energy into another form of energy
sensation
the transduction of physical energy into neurochemical impulse, the conduction of that impulse to the brain, and the registratio nof the impulse on the thalamus and cortex
perception
the interpretation of sensations
threshold
the intensity at which a stimulus can be detect 50% of the time
receptor cell
the cell responsible for trasnduction of physical energy
unipolar cell
a typical receptor cell
types of unipolar cells
rods and cones
rods
scotopic or protopathic

low threshold, low resolution

for night vision, don't require much light, not good for detail (vague)
cones
photopic or epicrtic

high threshold, high resolution

require a lot of light, good for high detail
bipolar cell
the first level integration of a number of receptor cells output

send action potential
ganglial cell
interpretation of sitmuli
errors in perception
erros begin at the level of transduction, but the learning process and context often change perception at highest levels

misinterpretation of sensation: illusion
amacrine cells
compensate for retinal blurring
horizontal cells
inhibitors of receptors
their inhibition spreads out in concentric fields and affects all receptors in the field whether they have direct stimulation or not.
the degree of inhibition is proportional to the degree of stimulation
high convergence
lower acuity
high sensitivity
several hundred rods to just 1 bipolar cell
low convergance
high acuity
low sensitivity
just one cone to one bipolar cell
lateral inhibition
principle of error compensation in many sensory systems

enhances contrast at edges for retinal receptors

receptors at the edge of stimulation receive less inhibition than stimulated neighbors. receptors at edge of non-stimulation receive some inhibition from stimulated neighbors.
the effect is a perceived enhanced contrast
primary visual cortex
registers visual information and passes it on

damage here means blindness
secondary visual cortex
passes perception on to tertiary cortex
tertiary visual cortex
integrates the information and conceptualizes it
primary cortex
detects and registers information
secondary cortex
perceives information
tertiary cortex
integrtes multi-modal information
suprachiastmatic nucleus
circadian rhythms
pineal gland
circadian rhythms, sensitive to light
superior colliculus
visual orientation and acctivation of supporting nuclei for ccomodation, focus, convergence, and eye movements
perceptual constancies
color, size, shape
afterimages
retinal fatigue and central processing
ambiguous figure
need of perceptual system to organize information
impossible figures
pressure to comperhend or make sense of world even when sense is not achievable
Uncus

aka

medial, anterior temporal cortex
the experience of smell
dorsal colum
carries information about touch and joint position.

this tract ascends ipsilaterally, crossing only at the level of the brain stem.

damage here will imapir sensation on the same side of the body
anterolateral system
crosses almost immediately and ascends contralaterally to the source of sensation into the thalamus and on to the cortex.

produces changes in sensation on the opposite side of the body
topographic/tonographic organization on the basiliar membrance and the cortex
the highest frequencies produce maximal vibratio non the area closest to the oval window, and lower frequencies further away. the lowest frequencies activate the entire membrane.

low frequencies: activates everything
high frequencies: activates only some parts higher up
tonotopica organization
low frequencies: medial and posterior areas
high frequencies: anterior and lateral areas
large component of meaning/experience
valence (value) and feelings
factors in determining appraisal of situation
genetics
immediate context
prevous experience with the situation
and recall of outcome of involvement
neural system of emotionality: cortical-limbic system
cortex: accesses current perception
memory: past history
autonomic: body states/reactions
TLH axis

temporal-limibic-hypothalamic
base of emotionality
affect
subjective and not observable by others
emotion
a personally relevant reaction to some specific object, situation, or perception that prepares a person to act in a specific way.
mood
predisposition to respond based on genetics, experience, perception, intellect, context, etc
reaction
immediate, cognitive and autonomic activity associated with a provocative situation
response
distinct somatic and autonomic signs.
allusions to emotions
references to what the viscera are doing: broken heart, butterflies in the stomach
blood : sanguine
mood outgoing, tolerant, affiliative
yellow bile : choleric
mood controlling, tense, organized
black bile : melancholic
mood ruminative, cautious, negativistic
mucous : phlegmatic
mood easy going, unruffable, unpredictable
James and Lange

Visceral theory
emotions were an afterward reaction to a situation by the gut. gut reactions then produce the emotion.

GUT FIRST, EMOTIONS SECOND

example: i am afraid because i'm running; i'm lonely because my chest hurts
Cannon and Bard

Thalamic theory
our perception of a situation at the thalamic level activates the gut.
feedback from the gut conveys the strength of the reaction

example: i am afraid, therefore i run
Papez and Maclean

Identified the limbic system
a system that is capable of integrating current perception with past experiences, and with the rapid effect on and feedback from the viscera.

connects the cortex to the hypothalamus
amygdala
territory, aggression, predation

recognizes the importance, novelty, potential threat, and/or emotional impact of the inew information and helps determine which memories are saved
septal nuclei
passivity, retreat, submit

activation suggests the new information has been recognized and is familiar.
no activation suggests the stimulus is novel and needs to be explored more.
hippocampus
connects the amygdala and the septal nucleus

where memories appear to be assigned to the appropriate cortex for teh information consolidation.
interacts with the medial temporal cortex and constantly with the prefrontal cortex to make sense of information or to work with the information to make it as meaningful as possible.
Zajonc

Facial reafference
contributes to the initial acquisition of emotoins and the later manifestations of subjective experience

example: kids falling down, look at parents reactions
Pribram

emotions
emotional reactions vs emotional responses
emotional reactions
inevitable and uncontrollable, just another form of information processing
emotional responses
a matter of experience and choice, just another form of problem solving
Pribam

2 brain systems involved in emotional experience
anterior/medial

lateral/posterior
Schachter and Singer

context and perception
emotional reactions of subjects consistent with context and perception.
anterior/medial
pleasure, hedonism, serotonin and dopamine-based
orienting response
a sudden departure from the expected = dissonance
lateral/posterior
aversive, recognize discomfort
emotions reflect perturbation
the emotion is information directing us toward satisfactory resolution of drive, thus emotions are a form of sensation-carrying information
medial limbic/hypothalamic/pituitary axis

MLHP axis
recognizes novelty, habituates, and recalls.

involved in reachieving homeostasis

EXCITATORY, EXPLORATORY, UNSTABLE, SENSITIZING

DEVIATE FROM BASELINE, CHANGE
lateralized systems (basal ganglia nd lateral limbic)
arousal and cortical desynchronization

basl ganglia: acting, anticipating, prepping set

INHIBITORY, REDUNDANT, GENERALIZING, STABLE, DEFENSIVE

REMAIN AT BASELINE, CONSERVE
Luria's 2nd functional unit
acquisition and retention of information
Luria's idea of consciousness
short term memory processes are consciousness.
memory
a collection of several integrated, but more or less discrete processes.
information acquisition
with sensation and perception
information processing
organization and comparison to existing information
encoding
the processes of setting up changes in the CNS, tagging, categorizing
storage
establishing the physical changes in teh CNS
maintenance
constant checking, reinterpreting, refreshing, and resisting forgetting
retrieval
returning stored information to consciousness in whatever degree.
feedback
accuracy check - influences the first stages from teh most recent retrieval.
orienting response
individual at rest, within homeostatic boundaries.
when novel information happens, baseline is disrupted
whole system alerts to increase and focus attention - symp nervous response creates a sense of novelty or salience.
amygdaloid in nature
habituation
with repeated presentations/exposures to novel stimuli, system becomes used to them.
basal ganglia beginning to expect or anticipate recurrence of stimuli.
orienting response is reduced with each exposure.
hippocampal/septal in nature.
4 domains of memory
visual
auditory
tactile
proprioceptive
(smell and taste not in it)
very short term memory
an echo of the stimuli in the structures that just processes them.
combination of hippocampus and other limbic structures with appropriate secondary cortexes
unlimited capacity
very brief duration
iconic/echoic
highly sensitive to interference
short term memory
a transition phase between sensory memory and long term memory in which information is held in order to be processed and made meaningful through rehearsal.

limited capacity
durability based on rehearsal
rote vs elaborative
working memory
an active process of using existing, acquired, understood information to process new information in order to make it memorable.
interaction of the temporal lobe and limbic system with the prefrontal cortex.
consolidation
new information is fixed in the brain.most active during REM sleep.
long term memory
permanent storage
possibily limitless capacity, unknown duration
episodic
memory for time and places
categorical
memory for categories
procedural
memory for activities or oeprations.
implicit and resists loss the best. you may lose nuance but not how to actually do the thing.
ACh
primary transmitter in cortical component of memory processes.
forgetting
non-pathological inability to remember information.

most common cause: interference, poorly learned infomation, lacked encoding, poorly organized, low effort, non-meaningful learning doesn't stick.
trace decay
over time, connections simply appear to break down.

information that isn't relevant to current life demands is placed ina kind of buffer that can be relearned in context.
nterference
proactive and retroactive
proactive interference
old information retards acquisition of new information
retroactive interference
new information retards recall of older information
amnesia
pathological forgetting usually after injury (trauma induced)

2 types
retrograde
prograde/anterograde
retrograde
events that happened before a trauma.
trauma interferes with the consolidation process.
prograde/anterograde
events that happen after a trauma.
the inability to learn new information.