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36 Cards in this Set

  • Front
  • Back

Molecular Genetics

The study of DNA, RNA, proteins, ect. (genetics on a biochemical level)

Mandelian Genetics

The study of how genes are inherited (genetics on a individual level)

Population Genetics

The study of how genes behave in a population (genetics on a population level)

Prokaryotic Cells

-do not possess a nucleus


-unicellular, but may form colonies


-examples: bacteria and blue-green algae

Eukaryotic Cells

-more complex


-contain various types of organelles


-can be unicellular (paramecia, amoebas) or multicellular (animals, plants, fungi)

Organelle

A specialized subunit within a cell that has a specific function and is usually surrounded by a membrane

Nucleus (Organelle of a Eukaryotic Cell)

Houses chromosomes

Mitochondria (Organelle of a Eukaryotic Cell)

Responsible for energy production

Ribosomes (Organelle of a Eukaryotic Cell)

Essential in protein manufacturing

Golgi Body (Organelle of a Eukaryotic Cell)

Collects and dispatches proteins

Somatic Cells (Type of Eukaryotic Cell)

All of the cells in the body except those involved in reproduction

Gametes (Type of Eukaryotic Cell)

Reproductive Cell




-Sperm in males


-Eggs (or ova) in females


-made by gonads (testes in males; ovaries in females)

Zygote (Type of Eukaryotic Cell)

Fertilized egg cell

Double Helix

DNA takes the form of a "twisted ladder" known as a double helix

DNA Structure Discovery

-Discovered in 1953


-Discovered by Watson, Crick, Wilkins, and Franklin

DNA Structure

DNA is made up of two strands of smaller molecules known as nucleotides

Three Components of Nucleotides

-a phosphate unit


-a sugar molecule (deoxyribose)


-one of four nitrogenous DNA bases

DNA Stands For:

DeoxyriboNucleic Acid

DNA Bases

Adenine (A) -purine


Guanine (G) -purine


Thymine (T) -pyrimidlnes


Cytosine (C) -pyrimidlnes

DNA Bases Continued

a purine pairs with a pyrimidine:


-Adenine (A) pairs with Thymine (T)


-Cytosine (C) pairs with Guanine (G)

Chromosomes

A DNA molecule is wrapped around specialized proteins called histones, coiled and coiled again




The end result of this coiling is a chromosome

Chromosomes (Continued)

-Often depicted as having an X shape


-Chromosomes in this depiction have already been duplicated in preparation for cell division (mitosis and meiosis)


-The two sides of the X are identical and known as sister chromatids


-The two sister chromatads are connected at the centromere


-The long arm of a chromosome is the q arm


-The short arm is the p arm

Chromosomes (Continued)

Chromosomes exist in pairs


-One from each pair is inherited from the mother and one from the father




Members of a chromosome pair are called homologous chromosomes


-Chromosomes in a pair influence the same traits, but the DNA may vary


-As such, they can produce different expressions of the same trait

Chromosomes (Continued)

Humans have 23 pairs of chromosomes (46 total)




The first 22 pairs of chromosomes are known as autosomes and numbered according to their length


-Chromosome 1 is the longest


-Chromosome 22 is the shortest

Sex Chromosomes

The 23rd pair of chromosomes are the sex chromosomes


-Females have two X chromosomes


-Males have an X and a Y chromosome

Meiosis

The process of creating gametes (sex cells)




The process of meiosis begins with a diploid cell, but the end result is four haploid cells, which have a half set of chromosomes

Recombination

The exchange of genetic material between homologous chromosomes during meiosis

Protein Synthesis

The second of the two primary functions of DNA

Proteins

Complex molecules formed from chains of amino acids such as:


Insulin - causes cells in liver and certain types of muscle tissue to absorb glucose


Hemoglobin - occurs in red blood cells; binds to oxygen


Collagen - most common protein in the human body; major component in all connective tissue

Proteins (Continued)

Proteins are made up of smaller molecules called amino acids

Amino Acids

All of the proteins in the human body are made from only 20 amino acids:




9 are obtained from dietary sources and known as essential amino acids




11 are produced in cells

Protein Synthesis

Protein Synthesis involves two steps: transcription and translation




In the nucleus, the DNA code is transcribed (copied) in the form of messenger RNA (mRNA)




Messenger RNA is then translated into a protein in the cytoplasm

Trascription

The formation of messenger RNA




Messenger RNA forms on the DNA template strands in the same manner as DNA replication

RNA

Similar to DNA but single stranded with a different sugar (ribose)




In RNA, thymine is replaced by uracil (A pairs with U instead)




After the mRNA strand is formed, it moves out of the nucleus to ribosomes in the cytoplasm, where the translation occurs

Translation

The "reading" of a segment of mRNA to assemble a protein

Codon

A triplet of mRNA bases that codes for an amino acid or the initiation or termination of the translation process




Each amino acid is attached to a segment of transfer RNA (tRNA) that pairs up with appropriate codon on mRNA




Amino acids are joined together in a polypeptide chain to form a protein