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319 Cards in this Set

  • Front
  • Back
Bone is a specialized _______ ________.
connective tissue
What are the general functions of bone tissue?
- mechanical
- physiological
Another name for bone tissue is
osseous tissue
More specifically, the functions of the skeletal system are:
mechanical:
- enable movement (through a lever system and points for muscle attachment)
- provide support (framework)
- provide protection (of internal organs)

physiological:
- provide storehouse for lipids and minerals (calcium and phosphate)
- enable hemopoiesis (production of RBCs and WBCs in the marrow)
Elements that comprise bone (osseous tissue):
- water
- proteins
- mineral salts
- vitamins
What mineral salts make up bone tissue?
- calcium (over 90% stored in bones)
- phosphorus
- magnesium
- boron and manganese (limited quantities)
- hydroxyapatite (makes bone matrix hard)
What vitamins make up bone tissue?
- Vitamin A1
- Vitamin B12
- Vitamin C
- Vitamin D
myelo-
marrow
osteomyelitis
acute or chronic bone infection
Without bones (and the calcium they contain) muscles _______
cannot move (they need the calcium ions)
The lamella in bone is full of ______ and ______
calcium and phosphorus
What hormones are associated with the skeletal system?
- thyroid hormone
- sex hormones
- somatotrophin (growth) hormone
- parathyroid hormone (parathormone)
- calcitonin
What hormones stimulate bone formation?
- thyroid hormone
- sex hormones
- somatotropin (growth) hormone
Is somatotropin (growth) hormone the same as HGH?
no

somatotropin (STH) is growth hormone 1, produced naturally (unlike "HGH")

HGH is produced by recombinant DNA technology (made in a lab)
What hormone stimulates osteoclasts to reabsorb bone, thus increasing blood calcium?
parathyroid hormone (parathrormone)
What will result if the function of parathyroid hormone (parathormone) is not balanced?
thinner bones

(hypercalcemic, hypercalcemia)
What is the function of calcitonin?
to inhibit the function of osteoclasts

lowers blood calcium level
What is the term for low blood calcium?
hypocalcemic
What organs and hormones are involved in homeostasis of blood calcium levels?
- calcitonin from the thyroid (lowers blood calcium)

- parathormone from the parathyroid (raises blood calcium)
How much of the total blood circulation is required by the bones?
10%
What active functional cells affect bone growth and development?
- osteoprogenitor cells
- osteoblasts
- osteocytes
- osteoclasts
- bone-lining cells
What is an osteoprogenitor?
an embryonic osteogenic precursur

(to osteoblasts)
What are osteoblasts?
cells associated with bone formation and development

cells that synthesize new bone matrix as needed
What are osteocytes?
mature bone cells that maintain bones
What are osteoclasts?
bone-destroying cells that create the bone marrow cavity

(so as osteoblasts build up the outside, osteoclasts eat away the bones from the inside)
What are bone-lining cells?
cells derived from osteoblasts that create a barrier around bone tissue
What active functional cells are involved in bone remodeling?
- osteoblasts
- osteoclasts
Osteoclasts are catabolic and are formed from
cells of the monocyte/macrophage line
Describe spongy bone
- site of red bone marrow in adults
- Haversian systems (osteons) are absent
Where is red bone marrow in adults?
- in the spongy bone

- pelvic bones
- ribs
- sternum
- vertebrae
- some skull bones
- ends of SOME long bones
What are the two modes of embryonic ossification/osteogenesis?
- intramembranous

- cartilaginous (endochondral)
What is intramembranous ossification/osteogenesis?
development that occurs directly on or within FIBROUS connective tissue membranes
Which bones are formed by intramembranous ossification/osteogenesis?
- flat bones of skull
- mandible
- clavicles
Which method of embryonic ossification/osteogenesis produces more bones?
about 90% of bones are formed by cartilaginous (endochondral) ossification/osteogenesis
What is the monophyletic theory of blood cell formation?
that all mature blood cells (RBC, WBC, etc.) are formed from one generalized stem cell

this stem cell is called the pluripotential (pluripotent) stem cell
Where are the hemocytoblasts (pluripotential stem cells) found?
among other places

- ilium
- sternum
Explain the steps in embryonic intramembranous ossification/osteogenesis
- mesenchyme (primitive connective tissue) differentiates into
- osteoprogenitor cells, then into
- osteoblasts, which secrete matrix, surrounding themselves and form
- osteocytes, which lie in lacunae, surrounded by calcium and hydroxyapatite deposits (ossification)

- vascularized mesenchyme outside the bone becomes periosteum
By what method of embryologic ossification/osteogenesis are most bones created?
approximately 90% of bones are created by cartilaginous (endochondral) ossification
Explain the formation of bone through embryologic cartilaginous (endochondral) ossification
- mesenchyme differentiates into
- chondroblasts, which produce hyaline cartilage (model); perichondrium develops around the cartilage model
- chondrocytes then cause interstitial growth (growth from within) which is followed by
- appositional growth (growth in thickness)
- chondrocytes then hypertrophy (change in matrix pH triggers calcification and differentiation into osteoblasts)
- compact bone forms
- perichondrium differentiates into periosteum
- capillaries grow and promote the periosteal bud
- primary ossification center is established
diaphysis
shaft of a bone
periosteum
fibrous membrane covering of a bone
Sharpey's fibers
fibers that penetrate from the periosteum into the bone
epiphysis
end of a long bone
articular cartilage
cartilage that covers the epipyhseal surface
epiphyseal plate
growth plate (youth)
epiphyseal lines
remnants of epiphyseal plate (in the adult)
marrow cavity
interior of the diaphysis
endosteum
lining of the shaft
metaphysis
between the epiphysis and diaphysis

during growth, this is the location of the epiphyseal plate
another term for osteon
Haversian system
Another word for Haversian system
osteon
What is the Haversian system/osteon?
the basic unit of the bone
Haversian canal
series of tubes around narrow channels formed by lamellae in the compact bone

parallel to the long axis of the bone

surround blood vessels, lymph vessels, and nerve cells throughout the bone and communicate with osteocytes in lacunae through canaliculi

conducive to mineral salt deposits and storage which gives bone tissue its strength

generally contains one or two capillaries and nerve fibers
osteocyte
a star-shaped cell found in compact bone, responsible for maintenance and turnover of the mineral content of the surrounding bone

when osteoblasts become trapped in the matrix they secrete, they become osteocytes

osteocytes are networked to each other via long cytoplasmic extensions that occupy tiny canals called canaliculi, which are used for exchange of nutrients and waste through gap junctions

the space that an osteocyte occupies is called a lacuna (Latin for a pit)
lacunae
small spaces (pit or cavity) containing osteocytes in bone or chondrocytes in cartilage
lamellae
concentric layers of calcified bone within an osteon
canaliculi
microscopic passageways between cells; radiate from lacunae

occupied by extensions of OSTEOCYTES

in bone, they permit diffusion of nutrients and wastes to and from osteocytes
Volkmann's canal
also known as perforating holes/canals, they are microscopic structures found in compact bone

they run within the osteons perpendicular to the Haversian canals, interconnecting the latter with each other and the periosteum

they also carry small arteries throughout the bone
Types/classifications of bone
- long bones
- short bones
- flat bones
- sesamoid bones
- irregular bones
- (sutural bones - sometimes used)
What are some facts about long bones?
- length greater than width
- determine length of extremities
- 2 epiphyses and 1 diaphysis
Examples of long bones
- femur
- humerus
- radius
- phalanges
Function of long bones
lever connection for ligaments
What are some facts about short bones?
- length, width (and thickness) are about the same
Examples of short bones
- carpals
- tarsals
Function of short bones
point of attachment for tendons

point of connection for ligaments
What are some facts about flat bones?
flexible and thin

generally flat(ish)
Examples of flat bones
- ribs
- sternum
- scapula
- most cranial bones
Function of flat bones
protection

(protect brain, internal organs)
What are some facts about sesamoid bones?
- generally roundish

- small bone imbedded within tendon
Examples of sesamoid bones
- patella
- pisiform of carpal bones
Function of sesamoid bones
to reduce friction
What are some facts about irregular bones?
don't fit any other category
Examples of irregular bones
- vertebrae
- facial bones
- temporal bone
Function of irregular bones
- support spinal cord
- protect against compression
What are sutural bones?
these are sometimes included as another category of bone

they are bones which develop in the cranial sutures
Describe the gross anatomy of a long bone
most consist of
- one diaphysis (tubular shaft)
- two epiphyses (ends of bone)
- metaphysis (junction between diaphysis and epiphyses)
- articular cartilage (layer of hyaline cartilage covering each of the epiphyses)
- medullary cavity
What comprises a metaphysis?
the epiphyseal (growth) plate and adjacent bony trabeculae of the spongy bone
What is a growth plate?
the place where bone continues to grow after birth
What type of cartilage is articular cartilage of long bones?
hyaline
What is contained in the medullary cavity?
marrow (either yellow or red)
Where are the medullary cavities containing yellow marrow?
in the diaphyses of bones
Where are the medullary cavities containing red marrow?
in the epiphyses of bones
What is yellow marrow
mostly fat

contained in medullary cavities of diaphyses
What tissue lines medullary cavities?
endosteum
What is periosteum?
outer cover of the bone
Where is periosteum absent?
at the articular surface
Of what two broad substances is bone comprised?
- matrix

- cells
Of what is the matrix of bone tissue comprised?
- ground substance
- inorganic salts
- collagenous fibers
How do inorganic salts and collagenous fibers affect bone?
- inorganic salts give bone its hardness

- collagenous fibers in the matrix give bone its strength and flexibility
What inorganic salts are noted in bone matrix?
- calcium phosphate

- calcium carbonate
How does the composition of bone matrix change with age?
older people have more inorganic salts (calcium phosphate and calcium carbonate) than collagenous fibers

thus their bones are less flexible and more brittle
What are the five types of cells comprising bone?
- osteoprogenitor cells
- osteoblasts
- osteocytes
- osteoclasts
- bone-lining cells
What are osteoprogenitor cells?
cells that undergo mitosis and that can be transformed into osteoblasts
Where are osteoprogenitor cells found in bone tissue?
- in the endosteum and

- in the deepest layer of periosteum
Where are osteoblasts found?
- in the periosteum and

- in growing portions of bones
What are osteocytes?
cells derived from osteoblasts

the main cells of fully developed bones
What function do osteocytes perform?
they regulate concentration of calcium in bodily fluids
Where are osteocytes found?
on the surface of bones
What are osteocytes?
cells derived from monocytes
What function do osteoclasts perform?
they are involved in bone resorption (breakdown)
Where are osteoclasts located?
on the surface of bones
What are bone lining cells?
cells derived from osteoblasts that form a barrier around bone tissue
Where are bone lining cells found?
on the surface of bones
What are the two types of bone?
- compact bone
- spongy bone
Describe compact bone
- forms bone's outer shell
- hard and dense
- comprised of osteons
Describe spongy bone
- does not contain osteons
- made of trabeculae (tiny spikes of bone)
- spaces between trabeculae
- designed to withstand stress and support shifts in weight
What is bone modeling?
alteration of a bone's size and shape during developmental growth
What is bone remodeling?
replacement of old bone tissue by new bone tissue

osteoclasts destroy old bone
osteoblasts lay down new bone
What hormones affect the remodeling of bone?
parathyroid hormone (parathormone or PTH) stimulates mobilization of calcium from bone (breakdown/destruction by osteoclasts) and blood level of calcium rises (hypercalcemia)

thyroid hormone calcitonin counters PTH action by slowing resorption (inhibiting action of osteoclasts) and lowering blood calcium level

should = homeostasis
What is a process?
an outgrowth, projection, prominence
What processes form joints?
- condyles - large rounded ends (e.g., of femur)
- heads - rounded articular projection supported by the neck of the bone (e.g., of femur)
- facet - small flat surface (e.g., of a vertebra)
What processes are sites for tendon and ligament attachment?
- crest - a ridge (e.g., iliac)
- epicondyle - outgrowth above a condyle (e.g., medial epicondyle of femur)
- linea - narrow ridge (e.g., linea aspera of the femur)
- spine - sharp, slender process (e.g., of scapula)
- trochanter - large projection present only on femur (greater and lesser)
- tubercle - small rounded projection (e.g., greater tubercle of humerus)
- tuberosity - broad, rounded, and roughened eminence (e.g., ischial)
- sinus - hollow space within the bone (e.g., frontal)
Name the processes of joint formation and the processes of tendon/ligament attachment
joint formation
- condyle
- head
- facet

tendon/ligament attachment
- crest
- epicondyle
- linea
- spine
- trochanter
- tubercle
- tuberosity
- sinus
Name some depressions and/or openings
- canal - narrow passageway (e.g., spinal canal)
- foramen - natural opening on a bone surface (e.g., obturator foramen)
- fossa - depression in a bone (e.g., mandibular fossa)
- groove - narrow surface (e.g., intertubercular groove "sulcus" of humerus)
- meatus - canal within a bone (e.g., external auditory meatus)
Name some depressions/openings
- canal
- foramen
- fossa
- groove
- meatus
What are the two major divisions of the skeleton?
- axial
- appendicular
What comprises the axial skeleton?
- skull (28 bones; 8 cranial, 14 facial, 3 pr auditory ossicles)
- hyoid (1)
- vertebral column (26/33; 7 cervial, 12 thoracic, 5 lumbar, 5/1 sacral, 4/1 coccygeal)
- ribs (24; 7 true pairs, 5 false pairs, 2 of which are floating pairs)
- sternum (1; 3 bones - manubrium, body, xiphoid process)
How many bones comprise the axial skeleton?
80
How many bones comprise the appendicular skeleton?
126
How many bones comprise the upper extremities? The lower extremities?
64

62
The axial skeleton forms the _______ axis of the body.
longitudiinal
What comprises the appendicular skeleton?
upper extremities and pectoral girdles

lower extremities and pelvic girdles
Name and number of cranial bones
- 1 frontal
- 1 occipital
- 1 sphenoid
- 1 ethmoid
- 2 parietal
- 2 temporal
Facts about frontal bone
- forms most of forehead and foundation of bone under eyebrow
- contains frontal sinuses
- supraorbital foramen
Facts about occipital bone
- forms majority of base of skull
- occipital condyles articulate with C1 (Atlas)
- foramen magnum
Facts about sphenoid bone
- winged (looks like butterfly)
- greater and lesser wings
- only cranial bone to touch all other cranial bones
- sella turcica - houses pituitary gland
- optic foramen
- superior orbital fissure
- foramen ovale
- "temple" bone
What is the only cranial bone that touches all other cranial bones
sphenoid bone
Facts about ethmoid bone
- in center of skull
- perpendicular plate (nasal septum)
- 2 superior concha (turbinates)
- 2 middle concha (turbinates)
- cribriform plate - openings for olfaction
- crista galli
- ethmoid sinus
Facts about parietal bones
- forms most of "roof" of cranium
- 4 sutures touch it
---- coronal
---- lambdoidal
---- sagittal
---- squamous
Facts about temporal bones
- zygomatic arch (process)
- petrous part (houses ossicles)
- mandibular fossa (for mandibular condyle--TMJ)
- mastoid process
- external auditory meatus
- internal acoustic meatus
- jugular foramen
- carotid canal
- styloid process
Facts about ossicles
- hammer (malleus)
- anvil (incus)
- stirrup (stapes)

they are in the temporal bones
Name the four skull sutures of the parietal bones, and the bones with which they articulate.
- coronal - with frontal
- lambdoidal - with occipital
- sagittal - with other parietal
- squamous - with temporal
Where does the spinal cord in an adult stop?
between L1 and L2
Where does the spinal cord in a child of about 12 stop?
between L3 and L4
Fontanelle names and locations
- anterior/frontal (between 2 frontal and 2 parietal bones--larger)

- posterior/occipital (between 2 parietal bones and occipital bone--smaller)

- also sphenoidal/anterolateral (F,P,S,T) and mastoid/posterolateral (T,O,P) laterally
What are the functions of the fontanelles?
- allow skull to compress for birth
- allow for rapid brain growth
- clinically significant in helping diagnose dehydration or intracranial pressure
Facts about the zygomatic bones
- 2
- form cheek bones
- articulate with temporal bone's zygomatic process
Facts about lacrimal bones
- 2
- in orbital cavity
- smallest facial bone
What is the smallest facial bone?
the lacrimal bone
Facts about the nasal bones
- 2
- form bridge of nose
- in contact with the frontal bone and 2 maxillas
Which 2 skull bones are paired?
- parietal
- temporal

others are frontal, occipital, sphenoid, ethmoid

total 8
Which 2 facial bones are not paired?
- mandible
- vomer
Facts about maxillae bones
- 2
- unite to form upper jaw (cleft palate when they don't)
- do NOT articulate with mandible (temporal + mandible = jaw/TMJ)
- palatine process
- alveolar processes
Facts about palatine bones
- 2
- compose posterior part of hard palate
- compose part of floor of nasal cavity
- compose part of floor of orbit
What is a suture?
an immovable joint found only in adult skull
What are fontanelles?
membrane-covered spaces between incompletely ossified sutures
How many paranasal sinuses in the skull?
- 4 pairs

- frontal
- ethmoid
- maxillary
- sphenoid
Facts about inferior nasal conchae (turbinates)
- not part of ethmoid bone
- below middle conchae and/or lateral wall of nasal cavity
Are the inferior nasal conchae part of the ethmoid bone?
no
Facts about the mandible
- 1
- largest and strongest bone of the face
- lower jaw
- contains alveolar processes
- part of the TMJ
What is the largest and strongest facial bone?
mandible
Facts about the vomer
- 1
- forms the inferior and posterior part of nasal septum
Name the 7 bones of the orbit
- frontal
- lacrimal
- ethmoid
- maxillae
- sphenoid
- palatine
- zygomatic
Name the 6 structures of the nasal septum
- ethmoid
- maxillae
- sphenoid
- hyaline cartilage
- palatine bone
- vomer
What are the 2 groups of sinuses?
- mastoid (1 pair - part of temporal bones)

- paranasal (4 pair - frontal, maxillary, ethmoid, sphenoid)
Maxillary and sphenoid sinuses are not fully formed until
the teenage years
Facts about paranasal sinuses
- lined in mucus and communicate with nasal cavity

- used in phonation (voice production)
Facts about paranasal sinuses
- lined in mucus and communicate with nasal cavity

- used in phonation (voice production)
Sinuses also
lighten the weight of the skull
Facts about the hyoid bone
- only true "floating bone" in the body
- inferior to tongue root
- superior to larynx
- used in muscle attachment between tongue and throat
Sinuses also
lighten the weight of the skull
Facts about the hyoid bone
- only true "floating bone" in the body
- inferior to tongue root
- superior to larynx
- used in muscle attachment between tongue and throat
vertebral foramen
contains spinal cord and its meninges

composed of vertebral arch and body
centrum (body)
bears weight

anterior to vertebral foramen
transverse process
lateral to vertebral foramen

muscle and ligament attachment
spinous process of a vertebra
most posterior part

muscle and ligament attachment
vertebral arch
posterior part that forms the vertebral foramen

comprised of 2 pedicles and 2 laminae
facets
surfaces used for articulation
laminae
form posterior arch of vertebral foramen
intervertebral foramen
lateral vertebrae openings through which blood vessels and spinal nerves pass
Main parts of a typical vertebra
- body
- vertebral arch
- several processes
What is atlas?
- C1
- called atlas because it supports the head (like Atlas supported the Earth)
- articulates with occipital condyles
- no body or spine
- permits "yes"
How many cervical vertebrae are there?
7
Each cervical vertebrae has _______ __________
transverse foramina
What is axis?
- C2
- articulates with atlas and C3
- forms pivot joint for atlas
- permits "no"
What is the dens?
- the odontoid process

- a protrusion that allows pivot of atlas
What is vertebra prominens?
- C7
- usually very visible through the skin
- long, unforked spinous process with a tubercle at the tip
transverse foramen
only in cervical vertebrae

allows passage of blood vessels
Facts about thoracic vertebrae
- T1 - T12

- articulate with ribs
Facts about lumbar vertebrae
- L1 - L5

- largest and strongest vertebrae; equipped for weight bearing

- provide attachment for lower back muscles
Facts about the sacrum
- S1 - S5 (fused)

- four ossified intervertebral discs
sacral hiatus
gap between S4 and S5

can administer caudal anesthesia here
sacral promontory
projecting anterior edge of S1
The sacrum supports
both the spinal cord and the pelvis
Facts about the coccyx
- Co1 - Co4 (fused)
intervertebral discs
located between the bodies of the vertebrae
The thorax is formed by
- bodies and intervertebral discs of 12 thoracic vertebrae
- 12 pairs of ribs, 12 costal cartilages and the sternum
Standard curves of the vertebral column
- cervical curve
- thoracic curve
- lumbar curve
- sacral curve
- coccygeal curve
Describe the cervical curve when viewed A/P
- concave at birth

- convex later so infant can hold head up
Describe the thoracic curve when viewed A/P
concave
Describe the lumbar curve when viewed A/P
- concave at birth

- convex later so infant can stand
Describe the sacral curve when viewed A/P
concave
Describe the coccygeal curve when viewed A/P
concave
What 3 parts comprise the sternum?
- manubrium
- body
- xiphoid process
Name three variations in curvature of the vertebral column
- scoliosis
- lordosis
- kyphosis
What is scoliosis?
abnormal lateral curvature of the spinal column
What is kyphosis?
severely hump-shouldered or hunchback curvature
What is lordosis?
swayback

abnormal lumbar curvature
How many true ribs?
False ribs?
Floating ribs?
- 7 pairs, each of which touches the sternum with its own cartilage

- 5 pairs, which share cartilage to the sternum (8-10) or do not touch the sternum at all (11-12)

- 2 pairs (11-12) which do not touch the sternum at all
What are intercostal spaces?
- space between the ribs

- filled with muscle, some nerves, and some vessels
A typical rib is composed of
- head
- neck
- shaft
The manubrium articulates with
- rib pair 1 and both clavicles
What is the sternal angle?
- between the manubrium and body

- where rib pair #2 attaches to sternum
What ribs articulate with the body of the sternum?
pairs #2 - #7
What is the xiphoid process?
the inferior end of the sternum

has no rib attachment
The appendicular skeleton is composed of
- the upper extremities
- the lower extremities

(and their respective girdles)
What is the most commonly broken bone?
clavicle
With what does the clavicle articulate (both ends)?
- medially with the manubrium

- laterally with the acromion process of scapula
How are the upper extremities connected to the axial skeleton?
- by one joint and many muscles

(sternoclavicular joint between the manubrium and clavicle)
Why are humans prone to shoulder separation?
because the pectoral girdle is held in place only by muscle and ligaments, rather than by the shape of the bone
Which is longer, radius or ulna?
ulna
Where are the heads of the radius and ulna?
- head of the radius articulates with the capitulum of humerus

- head of the ulna articulates with the carpals (distal)
What are the hip bones?
- ilium
- ischium
- pubis
What comprises the hip joint?
- acetabulum of os coxa

- head of femur
What is the pelvic girdle?
- 2 hipbones (os coxae)
- sacrum
- coccyx
How are the metacarpals numbered?
1-5

starting laterally (thumb)
Name the sesamoid bone in the wrist
pisiform

sesamoid bone within the tendon of the flexor carpi ulnaris
Where are the MCP joints?
- metacarpophalangeal joints

- between metacarpals and phalanges

- the knuckles of the hand
What are the joints between fingers called?
interphalangeal joints
Bones of the wrist
hamate capitate trapezoid trapezium

pisiform triquetral lunate scaphoid
What is the pollex?
thumb
When does the fusion of the three bones of the hipbones take place?
during adolescence
What are the 3 joints associated with the os coxa?
- sacroiliac joint
- sacrococcygeal joint
- symphysis pubis
What is the pubic symphysis?
the anterior joint where the hip bones are united
What is the acetabulum?
a fossa where the 3 hip bones fuse and where it receives the head of the femur to create a ball-and-socket joint
Which is the largest of the three hipbones?
ilium
What is the lowest and strongest of the three hipbones?
ischium
What structure bears all our weight when we sit?
ischial tuberosity
Which hip bone has the greater and lesser sciatic notches?
ilium
Does the fibula articulate with (touch) the femur?
no
What bones articulate to comprise the knee?
femur, tibia, patella
Describe the syndesmosis between the tibia and fibula.
a slightly movable articulation where continuous bony surfaces are united by interosseous ligament

a joint with a thick collection of connective tissue
Differences between male and female pelvises
- female pelvis is lighter and wider
- bone markings of female pelvis are less obvious
- female sacrum is less curved, thus greater distance between coccyx and symphysis
- ischial tuberosities are further apart and turned outward on female pelvis, thus pubic arch has wider angle
- pelvis has larger opening in the female
What is the longest, heaviest and strongest bone in the body?
femur
Function of the patella
muscle attachment

protection of knee joint
What is the largest sesamoid bone in the body?
patella
What is the largest bone in the body?
tibia

(not femur? largest how, diameter?)
Is the fibula weight-supporting?
no, only the tibia carries weight
What is the medial malleolus?
the distal end of the tibia

inner ankle

articulates with talus
What is the lateral malleolus?
distal end of the fibula

outer ankle

articulates with talus
Although the fibula doesn't bear any weight, it is important for ______
movement of the ankle
What is unique about the talus?
it supports ALL body weight, as it articulates with both the tibia and fibula
What do the distal heads of the metatarsals form?
the ball of the foot
How are the metatarsals numbered?
1-5 medial to lateral

starting at hallux
What is the highest (most superior/cephalic/proximal) bone of the foot?
talus
Names of tarsals
medial, intermed, lateral, cuboid
-------cuneiforms-----------
navicular, talus, calcaneus
What are articulations?
points of contact between
- bone and cartilage
- bone and bone
- bone and teeth
What are the anatomical classifications of joints?
- fibrous (little or no movement)
- cartilaginous (little or no movement)
- synovial (move easily)
By what two methods are joints classified?
- by their structure (presence or absence of joint cavity and supporting tissue binding bones together) (anatomical)

or

by the extent of their functions and/or degree of movement (physiological)
What are the physiological classifications of joints?
- synarthroses (immovable)
- amphiarthroses (slightly movable)
- diarthroses (freely movable)
Fibrous joints allow for little or no movement. What are three types?
- sutures (fibrous connective tissue between skull bones)

- syndesmosis (articulating bones united by dense fibrous connnective tissue; e.g., between shafts of radius and ulna)

- gomphoses (fibrous peg-and-socket joints; e.g., teeth)
Cartilaginous joints allow for little or no movement. Name two.
- synchondrosis (immovable temporary joint of hyaline cartilage joining diaphysis and epiphysis of growing long bones; epiphyseal plate)

- symphysis (bony surfaces bridged by plates or discs of fibrocartilage; slightly movable = amphiarthoses; e.g., symphysis pubis or intervertebral discs)
Synarthrosis definition and examples
joints which do not move

- suture (skull bones--fibrous)
- gomphosis (teeth--fibrous)
- synchondrosis (epiphyseal plates--cartilaginous)
Amphiarthrosis definition and examples
joints which have a little movement

- syndesmosis (radius-ulna, tibia-fibula---fibrous)
- symphysis (pubis, intervertebral discs--cartilaginous)
All diathrosis are ______
synovial
Synovial joint definition and 4 components of synovial joint
bones move freely on each other due to four basic structural features:
1) synovial cavity (space between the bones with synovial membrane which secretes synovial fluid for lubrication and easy movement)
2) articular cartilage (covers articular surfaces of the bones and provides shock absorption)
3) articular capsule (surrounds joint surfaces by enclosing synovial cavity and connecting articulating bones)
4) stabilizing ligaments (fibrous connective tissue that joins articulating bones)
Some synovial joints also contain
menisci (sing. meniscus)

pads of fibrocartilage between articular surface of the bones; help maintain stability and direct flow of synovial fluid to areas of greatest friction
What are bursae?
synovial fluid-filled connective tissue sacs which cushion the movement of one part of the body over another

between skin and bone
between tendons and bone
between muscles and bone
between ligaments and bone
between adjacent muscles

often associated with, but NOT part of joints!!
What are tendon sheaths?
long cylindrical sacs filled with synovial fluid which surround long tendons

keep things lubricated, reduce friction, and allow tendons to slide easily
Diarthrosis joints move
freely
What factors limit movement at a synovial joint?
- interference from other structures
- tension exerted by ligaments of the articular capsule
- muscle tension
Name the types of movement of a synovial joint
- flexion
- extension
- inversion
- eversion
- supination
- pronation
- abduction
- adduction
- circumduction
- rotation
- dorsiflexion
- plantar flexion
- protraction
- retraction
- supination
- pronation
- elevation
- depression
flexion
bending motion in which angle between two bones is decreased
extension
straightening motion in which angle between two bones is increased
inversion
movement of sole of foot inward (medially)
eversion
movement of sole of foot outward (laterally)
supination
pivoting movement of forearm in which radius is rotating to become parallel to ulna
pronation
pivoting movement of forearm in which the radius is rotated diagonally across ulna
abduction
movement of limb away from midline of body
adduction
movement of limb toward midline of body
circumduction
movement of which distal end of bone moves in circular motion while proximal end remains stable
dorsiflexion
to raise the top of the foot superiorly
plantar flexion
to lower the foot toward the ground
protraction
to protrude a part of the body anteriorly
retraction
to return a protruded part back to its original psotion
elevation
to raise a part of the body
depression
to lower a part of the body
unaxial joint
movement of a bone at a joint is limited to rotation about one axis

(e.g., extension/flexion of forearm)
biaxial joint
when two movements can take place about two axes of rotation

(e.g, hand moves up-down and side-side at the wrist)
multiaxial joint
three degrees of movement
(movement in a number of axes)

(e.g., shoulder joint)
What are the six major types of synovial joints?
- ball-and-socket joints
- condyloid joint
- gliding joints
- hinge joints
- pivot joint
- saddle joint
Describe a gliding joint
articulating surfaces are usually flat so one bone slides on the other bone

(e.g., carpal bones; SI joint)
Describe a hinge joint
spool-like surface of one bone that fits into the concave surface of another

uniaxial (flexion and extension)

(e.g., elbow, knee, ankle)
Describe a pivot joint
rounded, pointed surface of one bone articulates within a ring formed partly by bone and partly by ligament

(e.g., between atlas and axis)
Describe a saddle joint
opposing articular surfaces that look like a saddle

(e.g., carpometacarpal joint of the thumb)
Describe a ball-and-socket joint
composed of a globe-like head in one bone that fits into a cup-like concavity of another bone

(e.g., hip joint, shoulder joint)
Describe a condyloid (ellipsoidal) joint
modification of ball-and-socket joint in which most of the movements are possible (flexion, extension, abduction, adduction), but there is no rotational movement

(e.g., wrist joint)
What is one of the most complex and weakest joints of the body
the knee
What type joints are in sutures and gomphoses?
fibrous synarthrosis
Four components of a synovial joint?
1) synovial cavity/membrane
2) articular cartilage
3) articular capsule
4) stabilizing ligament
Pelvis is made up of which bones?
- ossa coxae
- sacrum
- coccyx
An immobile joint is called
synarthrosis
A movable joint is called
diarthrosis

amphiarthrosis has some movement
Give an example of a cartilaginous joint
- symphysis (pubis or intervertebral discs)

- synchondrosis (epiphyseal plates)
In which joints do you find menisci?
- knee
- TMJ
- both ends of clavicle (acromio and sterno)
What is the difference between syndesmosis and symphysis?
- syndesmosis is fibrous

- symphysis is cartilaginous
What are the two main hormones involved in calcium regulation between bone and blood?
- calcitonin from thryoid (lowers calcium in blood)

- parathormone from parathyroid (raises calcium in blood)
What structures allow children to grow lengthwise?
epiphyseal plates
What structures allow bones to grow width-wise?
lamellae

osteons

osteoblasts
A joint made of a thin fibrous tissue is a:
a. syndesmosis
b. suture
c. gomphosis
d. dianthrosis
b. suture
The joint between the fibula and tibia is
syndesmosis
The four components of a typical synovial joint are
- synovial cavity/membrane/fluid
- articular cartilage
- articular capsule
- stabilizing ligament
Two bones of the nasal septum
- perpendicular plate of ethmoid

- vomer
Basic unit of the compact bone
Haversian SYSTEM or osteon

(ensure it says SYSTEM and not CANAL!!)
During embryonic development, the flat bones come directly from
mesenchyme
Development of long bones is
endochondral
The hypocalcemic hormone of the thyroid is
calcitonin
The hormone which stimulates osteocytes to increase the level of calcium in the blood is
PTH

(parathormone)
Bone cells that develop in the periosteum and endosteum
osteoprogenitor cells or osteogenic cells
osteoprogenitor cells
these are the "stem cells" for bone. They have the capacity to divide and proliferate to form osteoblasts, bone forming cells which actively produce bone tissue. They comprise the periosteal and endosteal cells which line the bone and its cavities. In mature bone where growth and remodeling is not occurring these cells are quiescent, but they are thought to function in maintenance and nutritional support of the osteocytes in the underlying matrix, with which they connect by means of gap junctions.
osteoblasts
these are the "bone forming cells" which secrete the collagen and ground substance that constitutes unmineralized bone (osteoid), and subsequently are responsible for calcification of the matrix. These cells also communicate with one another and with osteocytes by gap junctions.
osteocytes
are mature bone cells, differentiated from osteoblasts, which are responsible for maintaining the bone matrix. They can synthesize and resorb (break down) the matrix to maintain homeostasis. Each osteocyte occupies a space, the lacuna, which conforms to the shape of the cell surrounded by matrix secreted when the cell was an osteoblast. Osteocytes extend processes through canaliculi to connect to neighboring cells by means of gap junctions.
osteoclasts
large multinucleated cells whose function is to resorb (reabsorb) bone. Osteoclasts dissolve the matrix and osteoid with acids and hydrolytic enzymes. Osteoclasts are phagocytic and are derived from monocytes and not from the same line as the other bone cells.
Three examples of fibrous joints
- suture (thin)
- syndesmosis (thick)
- gomphosis (teeth, peg)
Two examples of cartilaginous joints
- synchondrosis (epiphyseal plate)

- symphysis (intervertebral discs or pubis)
Example of synovial joint
all movable
Three examples of synarthrosis
NO MOVEMENT

- suture
- gomphoses
- synchondrosis (epiphyseal plate)
Two examples of amphiarthrosis
SOME MOVEMENT

- symphysis
- syndesmosis
Examples of diarthrosis
any typical synovial joint