Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
18 Cards in this Set
- Front
- Back
|
Myosin is a protein that
|
produces force that convert chemical potential into forces.
|
|
|
muscles are made of billions of contractile bundles
|
that made of thick and thin filament which pack tightly together to form sarcomi which hundreds of thousand of it make myofibril that make up muscle cell that make bundle of muscle fibers thatmake up muscle group.
|
|
|
Sacromeres are the basic
|
unit of the slding filament theory
|
|
|
contraction is fast
|
only 50ms for type-II fiber
5-10 ms: latent period" between siganl from brain and start of contraction 40-45 ms: contraction phases" from fully elongated to fully contracted. |
|
|
New ATP binding releases
|
myosin from the actin filament, the myosin is transferred to different affinity to actin.
Myosin head binds actin filament for a very short time |
|
|
Failure of myosin to detach n the absence of ATP cause
|
Rigor Mortis. ( example of the chicken wing)
|
|
|
Muscle
|
become meat when enter this state
|
|
|
The power stroke is understood at atomic resolution
|
the neck domain determined the swing of myosin which suggest that it might act as a level arm.
|
|
|
The neck domain of myosin acts
|
as a lever arm
|
|
|
Muscle faces 3 design challenge
|
1 prevent continuous contraction
|
|
|
The structure of sarcomeres is set by
|
nebulin , titin and capping proteins
|
|
|
Nebulin acts as
|
a ruler for the length of the thin filament
|
|
|
Titin
|
gigantic protein
|
|
|
How to prevent contacrtion ?
|
tropomyosin blocks the binding site for myosin on the actin filament.
|
|
|
Motor neuro stimulation cause a
|
rapid concentration of rapid spike in calcium in muscle fibers
|
|
|
The sarcoplasmic
|
reticulum is a calcium storing organelle
|
|
|
Muscle contraction is stimulated by the
|
presence of calcium.
|
|
|
Troponin binds calcium and
|
pulls tropomyosin out of the way.
|
