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7 Cards in this Set
- Front
- Back
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Saturation is?
A.the condition where all binding sites of all receptor molecules are bound with ligand. B. the ‘tightness’ with which a receptor binds its ligand and reflects the ligand concentration range over which the receptor will become saturated C. ‘fit’ between ligand and receptor where binding is limited to particular and generally small sets of related chemical compounds with particular stereochemistries. D.concentration of bound hormone E. A and B are both accurate |
A the condition where all binding sites of all receptor molecules are bound with ligand.
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Affinity is?
A.the condition where all binding sites of all receptor molecules are bound with ligand. B. the ‘tightness’ with which a receptor binds its ligand and reflects the ligand concentration range over which the receptor will become saturated C. ‘fit’ between ligand and receptor where binding is limited to particular and generally small sets of related chemical compounds with particular stereochemistries. D.concentration of bound hormone E. A and B are both accurate |
B. the ‘tightness’ with which a receptor binds its ligand and reflects the ligand
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Specificity is?A.the condition where all binding sites of all receptor molecules are bound with ligand.
B. the ‘tightness’ with which a receptor binds its ligand and reflects the ligand concentration range over which the receptor will become saturated C. ‘fit’ between ligand and receptor where binding is limited to particular and generally small sets of related chemical compounds with particular stereochemistries. D.concentration of bound hormone E. A and B are both accurate |
C. ‘fit’ between ligand and receptor where binding is limited to particular and generally small sets of related chemical compounds with particular stereochemistries.
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Kd is represented by all of the following except?
A. Determined from the slope= -1/Kd B. Is the dissociation constant C.Represented by the affinity D. Determined by slope= Kd/-1 E. All of the above are correct |
D. Slope = Kd/-1 is incorrect
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Which of the following accurately describes Ion channel signal transduction function?
A. selective opening by channel-linked receptors B. Leads to recruitment of SH2 domain containing effector proteins for either assembly into active complexes at the membrane surface C. Leads to direct gating D. Modulates second messenger levels by enzyme activity |
A. Selective opening by channel-linked receptors
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Which of the following accurately describes growth factor receptor signal transduction function?
A. selective opening by channel-linked receptors B. Leads to recruitment of SH2 domain containing effector proteins for either assembly into active complexes at the membrane surface C. Is performed through enzymatic activity D. Modulates second messenger levels by enzyme acti |
C. Is performed through enzymatic activity
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Which of the following accurately describes growth factor receptor signal transduction function?
A. selective opening by channel-linked receptors B. Leads to recruitment of SH2 domain containing effector proteins for either assembly into active complexes at the membrane surface C. Is performed through enzymatic activity D. Modulates second messenger levels by enzyme acti |
D. Modulates second messenger levels by enzyme activation and or leads to direct gating of ion channels
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