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75 Cards in this Set

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Second name for:
1- Vit A.
2- Vit D.
3- Vit E.
4- Vit K.
5- C.
6- B1.
7- B2.
8- B3.
9- B6.
10- H.
11- B12.
Retinoids.
Sterols(Cholecalciferol)
Tocopherols
napthoquinones
L-Ascrobic Acid
Thiamine
Riboflavin
Niacin
Pyrodoxin
Biotin
Cyanocobalamin
Polyisoprenoid
A
Isoprenoid side chain
E
# tocopherols
8
The name of the ring in:
A
D
E
B1
B2
H
Folic Acid
B12
Beta-Ionone
Cholesterol
Tochol or Chromane
Pyrimidine & Thiazol
isoalloxathine
Imidazol
Pteridine & PABA
Corrin
Tochopherols enter the lymphatics bound to
Chylomicrons & other lipoproteins
Transport in blood:
A
E
RBP
Lipoprotein
Alpha tocopherols are important because:
Widest distribution
Greatest biological activity
RDA E:
4 IU
12-15 IU
RDA k2:
50 microgram
Tocopherols act synergistically with
Selenium
Defici. E:
1- Hemolytic Anemia.
2- Muscle weakness.
Hypervitaminosis E
Hemorrhage
Rat Antisterility
E
Funct. E:
Prevents hepatic necrosis
enhances immune response
Side chains K1, K2
20
30
K3
Menadione
manandione's clinical importance
Water-soluble
K flora:
k2
Poor souces of K
Animal sources
Fruits
Funct. K:
Regulates synt. of prothrombin
Pro-convertin
Stuart-prower
Christmas factor
Prothrombin --> thrombin
Carboxylation of Gamma glutamte of prothrombin
inhibit hydroquinone:
Warfarin
Dicumarol
Oxidative phosphorylation
K
Newborn's deficiency
K
Hyp.vit. K
Hemolysis
hyperbilirubinemia
brian damage
Reduc. Fehlin & Bened
L-Ascrobic acid
Similar to sugars
L-ascorbic acid
Methemoglobin --> hemoglobin
C
Antioxidants
C
E
Beta-carotene
Decreases risk of cataract
Vitamin C
Weak bones, easily fructured:
C
D
Whole Grains
B1
RDA thiamine:
1.5 mg/day
TPP
Oxidative decarboxylation
Deficiency of thiamine:
BeriBeri
Wernicke's-Korsakoff
Tachycardia
Thiamine
Oothalmoplagia:
Paralysis of ocular muscles
Alcoholics
B1 Defic.
Decomposes by visible light:
Riboflavin
RDA riboflavin
1.5-2 mg/day
flavo-protein enzyme:
FAD
FMI
Protheric groups of oxidoreductase:
FMN
FAD
Hydrogen Carriers
Flaviproteins
FMNH2
FADH2
Transketolase
Thiamine
FMN:
Oxidate deamination
ATP-> oxidative phosphorylation
FAD
Carbohydrate metabolism
Lipids metabolism
Some AAs
Riboflavin deficiency:
Angular stomatitis
Inflammed lips
Glossitis
Scally dermatitis
60 MG tryptophan
Niacin
RDA Niacin:
20 mg
Coenzyme niacin:
NAD
NADP
NMN
NAD
Lactate dehydrogenase
Pyrruvate dehydrogenase
NADP
Folate reductase
Tryptophan->serotonin
Carcino syndrome
Pellagra
Niacin deficiency
3Ds
Dermatitis
Diarrhea
DementiaB6
Pyrodoxine
b6
Pyridine in urine
oxidized perodoxic acid
Most active Co of B6
Pyrodoxal phosphate
RDA B6
6 mg/day
Carbon Moiety
H4F
Biosynthesis of DNA
H4F
Alcoholics
Folic Acid
B6
B1
Hemocystein -> methionine
B6
B12
H4F
Folate antagonists:
methotrexate
sulfanamide
trimethotropin
Cobalt contain. vit
Cyanocobalamin
Vegetarian's deficiency
B12
Flora
K2
B12
Biotin
Cobalamin binds to
Intrinsic factor
Transportation B12 blood
TCII
Coenzyme of B12
Cobamide
Pernicious anemia
B12
Pentoic acid + beta alanine:
Pantothenic acid
Sulfur containin:
A
Lipoic Acid
pantothenic acid
Oxidative decarboxylation:
lipoic acid