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13 Cards in this Set

  • Front
  • Back
full term neonates normal at birth becomes mentally retarded and hyperactive within days and have musty sweats
alcoholic becomes hypoglycemic, why?
ethanol increases NADH, shunting pyruvate and oxaloacetate to lactate and malate, inhibiting gluconeogenesis
black urine and black spots in sclera
chest pain and xanthomas in Achilles tendon
LDL receptor defect in familial hypercholesterolemia
infant with failure to thrive and big tummy, brittle hair and skin depigmentation
alcoholic develop rash diarrhea and altered mental status
pellagra, vit b3 deficiency
how many histones and what are they?
H1+2xH2A+2x2B+2xH3+2xH4 = 9, to make heterochromatine, inactive transcriptionally
purine components
aspartate, glycine, CO2, N10-FTHF, and glutamine
pyrimidine components
aspartate and carbamoyl phosphate
transition is?
substitute a purine by another purine
transversion is?
substitute a purine by a pyrimidine or vice versa
DNA profreading/
DNA polymerase III has 5 to 3 synthesis and proofreading at 3 (exonuclease 3 to 5) while DNA polymerase I excise at 5 to remove RNA primer (exonuclease 5 to 3)
what drug inhibit RNA polymerase 2, what's the consequence
alpha-amanitin, inhibit mRNA synthesis