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13 Cards in this Set
- Front
- Back
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Phenylalanine - Derivatives
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Tyrosine --> Thyroxine + DOPA --> Melanin + Dopamine --> NE --> Epi
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Tryptophan - Derivatives
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Niacin --> NAD/NADP, Serotonin, Melatonin
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Histidine - Derivatives
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Histamine
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Glycine - Derivatives
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Porphyrin --> Heme
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Arginine - Derivatives
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Creatine, Urea, Nitric oxide
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Glutamate - Derivatives
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GABA (glutamate decarboxylase req B6)
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Phenylketonuria - Deficiency
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Phenylalanine hydroxlase or tetrahydrobiopterin cofactor
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Alkpatonuria - Deficiency
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Homogentistic acid oxidase in degradative pathway of tyrosine
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Albinism - Deficiency
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tyrosinase (can't synthesize melanin) or tyrosine transporters
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Homocystinuria - Deficiency
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cystathionine synthase (affinity for pyridoxal phosphate or deficiency), methionine synthase
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Cystinuria - Deficiency
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renal tubular AA transporter for COLA (cystine, ornithine, lysine, arginine)
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Maple Syrup Urine Disease - Deficiency
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Alpha-ketoacid dehydrogenase (blocked degradation of branched amino acids: Ile, Val, Leu)
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Hyperammonemia - Deficiency
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Liver disease or ornithine transcarbamoylase deficiency
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