Biochemistry 200

Front 1

What are the two types of gene expression?

Back 1

Constitutive (continuous expression of genes that are needed all the time) and

Internal regulation (genes that are not needed all the time and can be induced or repressed as necessary

Front 2

What is the difference between Positive regulation and negative regulation?

Back 2

In positive regulation, an activator (inducer) recruits RNA polymerase to a promotor site

In negative regulation, a repressor inhibits RNA polymerase from binding to the promotor side.


Effector molecules (co repressors) act in both cases to cause binding or dissociation

Front 3

Repressors/Activators are ____

Back 3

DNA binding proteins

Front 4

What are some of the common motifs for regulatory proteins

Back 4

Helix turn Helix, Zinc Finger and Leucine Zipper

Front 5

Helix turn Helix is involved in ____ ____ binding and is common in _____

Back 5

major groove; prok cells

Front 6

Zinc Finger motifs are involved in ____ ___ binding and are common in _____

Back 6

euk cells

Front 7

What is an operon?

Back 7

when the genes for proteins that are related in function are clustered into units on the chromosome

Front 8

Leucine Zipper motifs are found in _____ and are in volved in what kind of interactions?

Back 8

euk cells; protein protein interactions