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15 Cards in this Set

  • Front
  • Back
4 Types of Noncovalent Forces
1) Charge-Charge Interactions
2) Hydrogen Bonding
3) Van der Waals Forces
4) Hydrophobic Interactions
Charge-Charge Interactions
Electrostatic interactions between two charged particles
Can extend the longest distance
Hydrogen Bonding
Strongest noncovalent interactions
H atom bonded to N,O, S can be hydrogen bonded to another electronegative atom.
Van der Waals Forces
Weak, short range forces between uncharged molecules.
Occurs when outer orbitals overlap.
What are noncovalent interactions ' jobs in biomolecules?
* Stabilization of proteins and nucleic acids
*Recognition of one biopolymer by another
*Binding of reactants of enzymes.
What are biopolymers?
Macromolecules created by joining many smaller organic molecules (monomers).
Hydrophobic Interatcions
Interactions between nonpolar molecules & Water are not as favorable as are interactions b/t water molecules themselves.
Water molecules form cages around non polar molecules.
Aliphatic Amino Acids
Glycine (Gly,G)
Alanine (Ala, A)
Leucine (Leu, L)
Isoleuine (Ile, I)
Sulfur Amino Acids
Methionine (Met, M)
Cysteine (Cys, C)
Aromatic Amino Acids
Phenylalanine (Phe, F)
Tyrosine (Tyr, Y)
Trytophan (Trp, W)
Basic Amino Acids
Histidine (His, H)
Lysine (Lys, K)
Arginine (Arg, R)
Acidic Amino Acids
Aspartate Acid (Asp, D)
Glutamate Acid (Glu, E)
Asparagine (Asn, N)
Glutamine (Gln, Q)
Side Chains with Alcohol Groups
Serine (Ser, S)
Threonine (Thr, T)
Tyrosine (tyr, Y)
pH < pKa
Protonated form dominates (AH)
pH > pKa
unprotonated form dominates (A)