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9 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Protein digestion |
3- intestinal phase: Intestinal peptidase (tripeptedase, dipeptedase) to amino acids |
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Absorption of amino acids |
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Sources of amino acid ? Amino acid pool can biosynthesis? |
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Transamination |
The transfer of an amino (-NH2) group from an amino acid to a keto acid. Interconversion of amino acids which Catalyzed by a group of enzymes called transaminases ( aminotransferase ) |
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The salient features of transamination |
1- Require pyridoxal phosphate (PLP) vitamin B6 2- no free NH3 3- reversible reaction 4- both catabolic and anabolic of amino acids 5- finally concentrate nitrogen in glutamate 6- all amino acid except lysine, threonine and proline 7- serum transaminases are important for diagnosis and prognosis purpose 8- only two namely aspartate transaminase and alanine transaminases |
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Diseases of increasing transamination |
-In liver diseases Increase SGPT - ALT -In myocardial infarction Increase SGOT - AST
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Deamination |
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Urea cycle |
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Hyperammonemia treatment |
Higher than 50 mg/dl ... Oral administration of antibiotics (neomycin) |
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