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8 Cards in this Set

  • Front
  • Back
What type of molecules dissolve readily in water? And what type are insoluble?
Hydrophilic molecules--Polar organic molecules and inorganic salts-- dissolve readily in water.
Hydrophobic--Nonpolar-- substances are insoluble in water.
How can you calculate pH through [H+]?
What is the Hendersonj-Hasselbalch equation?
pH= -log [H+]

pH = pka + log [base]/[acid]

pH = pka + log [deprotonated]/[protonated]
What does a buffer consist of?
Buffer consists of a weak acid and its conjugate base.
What would be the patient's breathing pattern in case of metabolic acidosis? Why?
The patient will breath more deeply (hyperventilation). This is because carbonic acid forms CO2 + H2O. According to Le Chatelier's Principle, if CO2 is eliminated through hyperventilation, carbonic acid will decrease and form more CO2.
Which two factors determine the effectiveness of a buffer?
1. pKa relative to pH of solution. The greatest buffering capacity is at pH range near its pKa.
2. Concentration of buffer.
What will a decrease in pH do to cardiac output and blood pressure?
Low pH decreases cardiac output and blood pressure. (Increase in pH may cause arrhythmia).
What is Hyponatremia?
Hyponatremia occurs during water intoxication or low blood Na+. The water moves into the cell and cause edema.
What is Osmotic diuresis?
Increased urination due to the presence of some substances in Kidney tubules; example: glucose or diuretic medicine such as Mannitol.

Renal correction of acidosis: increased excretion of H+ and adding bicarbonate to blood.

Renal correction of alkalosis: decreased excretion of H+ and increased excretion of bicarbonates.