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6 Cards in this Set
- Front
- Back
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At what stage in the embryo are cells totipotent? What about pleuripotent?
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8-cell stage, all cells are toti-potent.
Blastocyst (80-100), cells are pleuripotent. |
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How can you make a stem cell out of a somatic cell?
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Somatic Cell Nuclear Transfer - Remove nucleus from egg, insert nucleus from somatic cell - the somatic nucleus gets reprogrammed by factors in the egg, act like a stem cell.
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What is a new theory of cancer involving stem cells?
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CSC - cancer stem cell. Some stem cells get messed up and can be driving cancer. Stem cells get mutations, replentish tumors. Most growth from CSC. May be slow-growing, so conventional therapies may not help.
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How is leukemia treated?
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Cord blood and bone marrow transplantation.
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What receptor is expressed on cancer cells that isn't normally found? On what cancer cell types?
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Folate!
Found on ovarian and lung cancer (no prostate). Can use to target SiRNA's, etc. |
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What is stem cell healing?
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remove marrow, isolate ASC's, re-implant later. Used in alzheimer's, parkinson's, spinal cord injury, diabetes, MS.
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