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18 Cards in this Set
- Front
- Back
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Progeria
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Dermatan S04 problems
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Lesch-Nyan Syndrome
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GTRPase malfunction-lost salvage pathway
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Azaserine
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Antibact-glutamine analog-Blocks APRT (purine synthesis )
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Sulfonamides (Methotrexate)
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inhibit purine synth
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Folate analogs
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Inhibit purine synth
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Allopurinol
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Inhibits Xanthine oxidase-gout treatment/prevention
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5BU
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Thymine analog; transforms AT to CG (transversion)
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Hydroxylamine
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Alkylating agent (tranversions)
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Cyclophosphamine
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Transversion
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Quinine
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Acryl die: intercalates bw base pairs and deletions or insertions
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Alpha amanatine
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Death cap: Blocks RP II (no mRNA synth and you die)
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Rifamycin
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Treats tuberculosis: Antibiotic inhibiting initiation of transcription
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Actinomycin-D
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Chemotherapeutic agent: Inhibits initiation of transcription
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Streptomycin
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Antibiotic binding to small subunit and blocks initiation
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Puromycin
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Occupies A site of Ribosome (its like a tRNA) and causes early termination
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Chloramphenicol
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Antibacterial: Inhibits peptidyltransferase in prokaryotes
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Cycloheximide
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Inhibits peptidyltransferase in eukaryotes
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Diptheria toxin
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Eukaryotic elongation factor (eEF2)
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