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19 Cards in this Set
- Front
- Back
what is the post absorbative values?
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4.5-5.5 mM
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glucokinase has a higher or lower km in relation to hexokinase?
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hihg
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is glucokinase inhibited by G6P?
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no
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glucagon synthase stimulates glycogensis where in the body?
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muscle and liver
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glucagon is reguated by what kind of feedback?
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negative
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growth hormone has what kind of effects?
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anti-insulin (lypolysis) and insulin like effects
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type 1 diabetes is what kind of rxn?
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autoimmune destruction of beta cells
absolute lack of insulin |
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insulitis is caused by?
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infiltration of t-lymphocytes
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what are the two factors associated with type 1 diabetes?
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environmental and genetic
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what are used in ketosis-> ketoacidosis?
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fatty acids
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type 2 diabetes is characterized by?
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beta cell loss and insulin resistance
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insulin resistance is related to
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obesity
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treatment of type 2 diabetes
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weight reduction, exercise, diet control
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obesity is caused by
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genetic basis (polygenic disease)
inbalance between energy uptake and energy expenditure |
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Leptin controls what?
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Ob gene control of appetite and metabolic rate
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Human obesity is caused by?
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resistance to leptin
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Ghrelinn regulates
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appetite, it is secreted into the stomach
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cholecystokinin is regulated by
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comes from the gut and sends messages to the brain
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Formula for BMI
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(wt. in kg)/(height in m)^2 or
(lb)/(inches)^2 x 703 |