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19 Cards in this Set

  • Front
  • Back
what is the post absorbative values?
4.5-5.5 mM
glucokinase has a higher or lower km in relation to hexokinase?
hihg
is glucokinase inhibited by G6P?
no
glucagon synthase stimulates glycogensis where in the body?
muscle and liver
glucagon is reguated by what kind of feedback?
negative
growth hormone has what kind of effects?
anti-insulin (lypolysis) and insulin like effects
type 1 diabetes is what kind of rxn?
autoimmune destruction of beta cells
absolute lack of insulin
insulitis is caused by?
infiltration of t-lymphocytes
what are the two factors associated with type 1 diabetes?
environmental and genetic
what are used in ketosis-> ketoacidosis?
fatty acids
type 2 diabetes is characterized by?
beta cell loss and insulin resistance
insulin resistance is related to
obesity
treatment of type 2 diabetes
weight reduction, exercise, diet control
obesity is caused by
genetic basis (polygenic disease)
inbalance between energy uptake and energy expenditure
Leptin controls what?
Ob gene control of appetite and metabolic rate
Human obesity is caused by?
resistance to leptin
Ghrelinn regulates
appetite, it is secreted into the stomach
cholecystokinin is regulated by
comes from the gut and sends messages to the brain
Formula for BMI
(wt. in kg)/(height in m)^2 or
(lb)/(inches)^2 x 703