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39 Cards in this Set
- Front
- Back
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True or false, all intermediates of the TCA cycle are not glucogenic?
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false, they all are
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glucogenic
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means it can go to glucose via oxaloacetate
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OAA ->_______ ->purines &pyrimidines
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aspartate
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alpha-ketoglutarate->_______->glutamine->________
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alpha ketoglutarate-> glutamate->glutamine->purine & pyrimidine
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Succinyl-CoA -> _____
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heme
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Citrate-> ______
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fatty acids
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_____ is the replenishment of intermediates
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anaplerotic reaction
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what enters at OAA, alpha-KG, succinyl CoA and fumarate
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amino acids
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amino acids are formed from what?
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anaplerotic reactions
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true or false, in the glyoxylate cycle, you are passing intermediates?
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true
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in glyoxylate cycle acetyl CoA gets transferred into?
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OAA
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true or false, the glyoxlate cycle occurs in animals?
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false, it only occurs in plants, algae, and some bacteria.
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In the glyoxylate cycle, succinate goes to what?
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malate
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the remainder of energy from substrate level phosphorylation-ATP and glycolysis & GTP in TCA goes to
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electron transport chain coupled to phosphorylation
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the carriers in the electron transport chain are unique because they are
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embedded into the inner mitochrondrion membrane
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The outer membrane of the mitochondion is a good barrier?
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no, its only about 50% selective of lipid, proteins, and cholesterol
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The inner membrane of the mitochondrion is a good barrier?
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yes, its is about 75% selective of protein, NO CHOLESTEROL
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what is the unique P-lipid for the inner mitochondrial membrane?
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cardiolipin
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where is ATP synthesis really taking place in the mitochondrion?
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the cristae
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as electrons pass along the chain in oxidative phosphorylation a ___ gradient is created across the membrane
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H+
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What drives the ATP synthesis in oxidative phosphorylation?
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the electrochemical gradient
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True or false. If you oxidize something, you must have something to accept the electrons?
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true
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The flow of electrons goes from
-ve to ____ and +ve to ____ |
more neg. ve
more positive ve |
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What are the 5 components of the Electron Transport Chain?
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Flavoproteins
Ubiquione-Coenzyme Q Cytochromes (proteins) Iron-sulfur (proteins)(NOT AS HEME) Protein bound Cu |
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How many distinct complexes can be distinguished from the mitochondrial membrane?
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five
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which of the complexes function in electron transport?
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1-5
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Which complex is the ATP syntaase?
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5
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electrons are pumped in which of the complexes?
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1, 3, and 4
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electrons are not pumped in which of the complexes? `
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2
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complex 3 converts what to what?
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CoQ -> cytochromes
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complex one converts what to what?
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NADH -> CoQ
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Complex two converts what to what?
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FADH2 -> CoQ
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complex four converts what to what?
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cytochrome -> Oxygen
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complex four accepts e- and makes?
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water
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what is the overall reaction in kJ/mol of oxidation of NADH?
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-220 kj/ mol
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protons are pumped from teh matrix to the _____
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intermembraneous space
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true or false, an electrochemical gradient is involved in the pH gradient?
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true
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as H increases pH does what?
in the ETC |
decreases, becomes more acidic
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as H decreases pH does what?
in the ETC |
increases, becomes more alkaline
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