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70 Cards in this Set
- Front
- Back
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The buffering power of a system is maximal at
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the midpoint of the buffering region
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The Henderson-Hasselbach equation involves
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the log of the conjugate base
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At very low pH (close to 0) the predominant species of a simple aminoacid is
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the fully protonated form
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The pKa of the amino group in an aminoacid is
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lower than a simple aliphatic amine
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The Henderson-Hasselbach equation can be used in an aminoacid to calculate
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the amounts of proton –donor and proton-acceptor in a buffer
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The aminoacids with the least propensity to form alpha-helix are
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Pro and Gly
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Chaperones, like Hsp70
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e. bind to unfolded polypeptides in regions of hydrophobic residues
f. protect proteins subject to denaturation by heat g. block the folding of certain proteins that must translocate |
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If the aminoacid residue coordinated to the heme in myoglobin were to be replaced, the best fit based on polarity and charge would be
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Arg
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The transition state in an enzymatic reaction is
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a fleeting molecular moment where decay to S or P is equally likely
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The Michaelis-Menten equation was derived based on the hypothesis that the rate-limiting step in enzymatic reactions is
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the breakdown of the complex to give E + P
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Lectins are
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proteins that bind carbohydrates with moderate affinity
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At low pH the purine and pyrimidine bases
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are charged with good water solubility
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Denaturation of a DNA molecule involves
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an increase in UV absorption of the solution
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The denaturation temperature (tm) of a DNA molecule
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is higher when G is higher
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A phosphoanhydride bond
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has more energy than a phosphate ester bond
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The carbon in methanol (CH3OH) and formaldehyde (H2C=O) differ in oxidation number by
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2
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A reaction most likely will be exergonic when
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a. delta H is negative
b. delta S is positive c. delta G is negative |
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Comparing glucose, NaCl, MgPO4 and MgCl2, the substance causing the most depression in melting point in ice when added in equimolar amount is
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MgCl2
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An example of a polar uncharged aminoacid is
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Thr
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The number of asymmetric centers in an aldoheptose is
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5
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Ninhydrin is used to
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detect free aminoacids
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When ammonia (NH3) is dissolved in water, the conjugate acid is
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NH4+
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"Foremost” is the word that means
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protein
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Chymotrypsin hydrolyzes
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carboxy groups from Trp, Phe and Tyr
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Protomers are
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the identical units of an oligomeric protein
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Beta sheet
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has interchain H-bonding
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Homologous proteins
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a. contain invariant residues
b. perform the same function in different animals c. contain variable residues |
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Denaturation
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destroys the native conformation of a protein
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Permanent waving involves
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the reduction of disulfide bonds followed by oxidation
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Antiparallel Beta sheet
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has a larger period that parallel
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The quaternary structure of proteins
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can’t have covalent bonds among subunits
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An aglycone is
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a group attached to a sugar
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A chaperone is
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a small protein required for folding
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An example of a fibrous protein is
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keratin
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A lyase is an enzyme that
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forms double bonds
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The rate constant in an enzymatic reaction
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gives the probability of a reaction under given conditions
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D-erythrose is an aldotetrose that has
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2 asymmetric centers
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D-xylulose is a ketopentose that has
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2 asymmetric centers
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The number of epimeric carbons in fructose (a ketohexose) is
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3
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Fehling’s reagent
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is an oxidizing agent
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Leptin acts thru
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kinase or phosphatase cascade
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Fats are a better storage form because
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They don't increase the osmotic pressure
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Perilipin
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Serves as a protector for lipid storage
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Carnitine is
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An aminoacid
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The carnitine shuttle
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Brings FA from the cytosol to the matrix
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The first step in the transport of FA is
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The formation of an adenosyl monophosphate derivative
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In beta-oxidation, a hydratase
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Makes an alcohol
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An FA of 17 carbons
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Will go entirely thru CAC
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Statement: A carboxylase requires ATP and biotin, an epimerase converts D-methylmalonyl CoA to L-methylmalonyl CoA and succinyl CoA will enter CAC
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statement
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Abnormal proteins
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Are degraded in proteasome
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The term PEST refers to the aa
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Pro, Glu, Ser, Thr
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The equilibrium of aa in the body is maintained by
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a. Muscle and liver
b. Muscle, liver and kidney c. Muscle and kidney d. None of the above |
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The best vehicle for N transport is
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Ala
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Ala is made by
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Transamination of pyruvate
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Humans are ureotelic because
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Mainly produce urea with some uric acid and ammonia
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Ile is made in the body
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a. By isomerization of Leu
b. From l-ketoglutarate c. From 3-phosphoglycerate d. None of the above |
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Cys is made in the body from two other aa, the most likely candidates for its synthesis are
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Ser and Met
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The branched-chain aa are
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A. (Val, Ile, Leu)
b. Pro, Ile, Val c. Leu, Thr, Ile d. Val, Ile, Lys |
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Removal of the amino group of aa is the first catabolic step except for
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Pro, Thr, Lys
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An oxidase
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Uses O2 as the acceptor
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Acyl CoA synthase is located in the mitochondrion
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In the outer membrane
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An uncoupler
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Allows the passage of H+ thru the inner membrane
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The chemiosmotic theory involves the processes of
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Respiration and ATP synthesis
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To produce 1 molecule of O2 thru photosynthesis
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4 electrons must be exchanged
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Plastocyanin is
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a. The same as cytochrome c
b. The same as cytochrome b6f c. The same a PSI d. None of the above |
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If the energy of an Einstein of photons at 700 nm is 171KJ, at 1,200 nm the energy of an Einstein of photons will be
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Lower
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Rubisco stands for
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Ribulose 1,5 bisphosphate carboxylase/oxygenase
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Based on the name, Rubisco I must be involved in
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Insertion of CO2 and transfer of O2 into substrates
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Usually the electron carrier for anabolic reactions is
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NADPH
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If CoA in AcCoA carries 2 carbons , in MalonylCoA it carries
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3
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