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23 Cards in this Set
- Front
- Back
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fructose uptake mechanism in gut?
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facilitated diffusion; glucose and galactose absorbed by Na cotransporter
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which sugar acid is conjugated to bilirubin?
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glucuronic acid
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enzyme that cleaves alpha-1,4 linkage in glycogen, releasing glucose units?
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glycogen phosphorylase
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which type of linkages are in plant fiber, and cannot be digested?
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beta-1,4 linkages; starch has alpha-1,4 linkages
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major difference between starch and glycogen?
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starch primarily found in plants and less branched than glycogen
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two essential fatty acids?
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linoleic and linolenic
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which shuttle moves fatty acid into mitochondria? out of mito?
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carnitine and citrine
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which two sphingolipids are found in the myelin sheaths?
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cerebrosides and gangliosides;
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three precursors for steroids in body?
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cholesterol, vit. D, and bile acids
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MOA of dipyramidole?
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block thromboxane A2 synthesis, decreasing platelet aggregation and vaso and bronchoconstriction
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three amino acids increased in maple syrup urine disease?
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leucine, isoleucine, and valine
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two hormones that increase amino acid uptake in muscle?
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GH and insulin
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which aa has positive charges in physiological pH? negative charges?
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lysine, arginine, and histidine have positive charges; aspartate and glutamate have negative charges
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two aa involved in collagen crosslinking?
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proline and lysine hydroxylation by ascorbic acid
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which aa involved in sickle cell?
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glutamine is changed to valine in sickle cell by a missense mutation
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aa involved in connection between two alpha-helix; commonly found in transcription factors?
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leucine creating the "leucine zipper"
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which metal involved in DNA-binding domains that interact with lipid-soluble hormones such as cortisol?
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zinc
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which metal is a cofactor for kinases?
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Mg
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which metal is cofactor for glutathione peroxidase?
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Se
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which conformation of Hgb is associated with O2 binding? unbinding?
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oxygenated R form and deoxygenated T form
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which chromosome involved in beta-thalassemia?
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chromosome 11
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which two kinds of Hgb is increased in beta-thalassemia?
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HbF and HbA2
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alport syndrome involved which type of collagen?
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type IV (basement membrane)
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