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21 Cards in this Set
- Front
- Back
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examples of base structures
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examples of nucleoside structures
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examples of nucleoside structures
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nucleotide structure examples
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The first step in pyrimidine biosynthesis
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note the structure and functions of carbamoylphosphate synthetase II
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second step of pyrimidine synthesis. happens right after making carbanoylphosphate. ends in an acid
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pyrimidine synthesis part 3, starting w/ an acid, ending with a NMP
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turning UMP into CTP. 4th step of pyrimidine biosynthesis
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pyrimidine synthesis regulation in bacteria
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Structure of E. coli aspartate transcarbamoylase and graph of it's activity vs [Aspartate]
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what are the conformational states of E. coli transcarbamoylase?
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unbound "taught" state and bound "relaxed" state in the catalytic region. C = catalytic region, R = regulatory region
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mammal pyrimidine synthesis enzyme
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regulation of formation of carbamoylphosphate in mammals
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draw out the building blocks of purines. there are 5
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basic structure that leads to all purines
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how many steps are in purine synthesis? What is the first and last step?
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11 steps. 1st step is PRibosePP + Gln. last step is IMP --> AMP and GMP
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what is the first structure that all other parts add to in purine synthesis?
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everything is built up off of a ribose
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What is a key difference in bacterial and animal synthesis of purines?
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bacteria use up one more molecule of ATP
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getting from IMP to GMP or AMP
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purine regulation
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