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10 Cards in this Set
- Front
- Back
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What is the difference between substrate level phosphorylation and oxidative phosphorylation?
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Substrate level phosphorylation is a phosphate transfer, while oxidative phosphorylation uses energy to add a free phosphate. G-3-P dehydrogenase reaction is an example of substrate level phosphorylation (Step 6 of glycolysis).
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What does it mean if FA's are "unesterified"?
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They are free FA's floating around in the body.
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What are 4 types of catabolism of FA's?
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beta-oxidation
Peroxisomal oxidation (VLCFA) Omega-oxidation Alpha-oxidation |
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Serum albumin carries FA from adipocytes to other tissues. What carries FA's from the intestine to other tissues?
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Chylemicrons carry FA's from the intestines as triacylglycerols.
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How does sulfonyluria help to treat diabetes?
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They act on the K+/ATP channels on the surface of b-cells in the pancreas. Sulfonyluria closes this channel which increases Ca2+ coming in to the cell and subsequent release of insulin.
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In biochemical terms (mM) what is a normal blood glucose? What's the range?
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-5 mM
-3-8 |
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How many hours after eating is glygogen usage and gluconeogenesis of equal importance?
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Approximately 16 hours after eating. Glycogen is trending downward (will poop out around 28 hours) and gluconeogenosis is picking up (started around 4 hours when exogenous glucose was used up).
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What end is the reducing end of glycogen?
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-OCOH is at reducing end
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Why store glucose as polymer (glycogen)? Why branching?
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-Reduces osmolar effects
-Branching allows more rapid degradation |
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Recall that glycogenesis can prevent hyperglycemia and hypoglycemia.
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Check!
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