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39 Cards in this Set

  • Front
  • Back
alpha 1
vasoconstriction
alpha 2
inhibit SNS, inhibit insulin release
beta 1
increase heart rate, contractility, renin release, acqueous humor formation, lipolysis
beta 2
vasodilation, bronchodilation, increase glucagon release
M1
CNS
M2
heart decrease
M3
exocrine glands increase
D1
renal vasodilation
D2
modulate transmitter release in brain
H1
pruritus, pain, bronchoconstriction, increase mucus production
Type I Collagen
bone, tendon, skin, fascia, cornea, late wound repain, dentin
Type II Collagen
Cartilage, nucleus pulposus, vitreos body
Type III
skin, blood vessels, uterus, fetal tissue, granulation tissue
Type IV
basal lamina, basemnet membrane
Type X
epiphyseal plates
Collagen formation
hydroxylation of lysine, proline in ER
glycoslyation of lysine in Golgi;
triplex procollagen formed adn released into ECM
Ends cleaved to insoluble tropocollagen;
fibril formation with lyslyl oxidase to stablize alpha chain triplets
Primary sequence of colalgen
glycine-X-Y; X - proline, Y hydroxyproline or hydroxylysine
Ehlers Danlos
defect in lysly oxidase, cannot form cross links;
extensible skin, mobile joint, easy bruising
Inheritance variable, 10 types;
associated with berry aneurysm
Scurvy
Vit C deficieny
defect in hydroxylation of lysine
bleeding gums, easy bruising
Osteogenesis imperfecta
AD (DOsteo)
Bone fractures, blue sclerae, loss of hearing, lack, of dentition (eye, ear, mouth, skull)
Defect in glycosylation of chain
Type II - fatal in utero or neonatal
Incidence 1:10 000
ATP 2 phosphoanhydride bonds
7 kcal/mol each
Aerobic metabolism via malate shuttle
38 ATP
Aerobic metabolism via G3P shuttle
36 ATP
Anaerobic metabolism
2 ATP
Phosphory
ATP
Electrons
NAD, FAD, NADPH
Acyl
coenzyme A, lipoamide
CO2
biotin
1 carbon units
THF
CH3
SAM
aldehyde
TPP
glucose
UDP
Choline
UDP
Glutamate
GABA
Fructose 6 Phosphate
Fructose 1,6 bis P (via PFK)
rate limiting enzyme of glycolysis
Pyruvate - Oxaloacetate
pyruvate decarboxylase
Oxaloacetate - PEP
PEP carboxykinase
F1,6BP - F6P
F16BPase
G6P - Glucose
G6Pase