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11 Cards in this Set
- Front
- Back
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What types of lipids are used for:
energy storage transport? |
energy = FAs
storage = TAGs transport = TAGs in lipoproteins, free FAs bound to albumin |
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What enzymea and products come from lipid digestion of:
cholesteryl ester phosphatidylcholine triacylglycerol |
cholesteryl ester --cholesteryl esterase--> cholesterol
phosphatidylcholine --lipases--> glycerylphosphorylcholine + 2 FAs triacylglycerol --pancreatic lipase--> 2-monacylglycerol |
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What do lingual and gastric lipases catalyze the digestion of? What kind of enzymes are they?
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TAGs containing FAs with short of medium chains
they are acid stable enzymes so they wont be destroyed or denatured by high pH (digestive tract) |
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When are lingual and gastric lipases important?
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neonates (milk fat) becuase it doesnt have long chains
cystic fibrosis (no pancreatic lipase) |
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What is emulsification?
What facilitates it? |
increases the surface area of lipid droplets for better digestion for TAGs with long chain FAs
bile salts and peristalsis facilitate it |
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Where are bile salts produced? stored?
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produced by liver from cholesterol
stored in gallbladder |
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What hormone stimulates the release of bile salts from gall bladder?
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cholecystokinin
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what can we eat to decrease the amount of recycled bile?
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diet rich in fiber
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TAG degradation:
what removes FAs? What results? What helps with this? |
esterase (pancreatic lipase) removes FAs from TAGs > 2 monacylglycerol + free FAs
colipase binds to lipase for better digestion |
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What drug inhibits lipases?
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Orlistat
anti-obesity drug > undigeste dlipids > fat malabsorption > weight loss affects digestion not actual absorption also results in deficiency of vitamins that are fat solible |
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What enzyme does cholesterol ester degradation? What results?
What helps it out? |
cholesterol ester hydrolase (cholesterol esterase) hydrolyzes cholesterol esters into free cholesterol and free fatty acids
bile salts increase its activity |
