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15 Cards in this Set

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Linkage
when two genes are so close they usually segregate together during inheritance.
Note: this is a violation of independent assortment.
cis and trans conformation
cis- alleles for two genes on the same homolog are both dominant or both recessive
---BE---
---be----
trans- dominant and recessive alleles on different homologs
---Be---
---bE---
Two heterozygous loci are cis to each other; If these loci are far apart what is the chance of a crossover occurring between them?
Great chance; recombinant trans progeny are produced. If the loci are close together crossovers between them will be rare.
Because alleles tend to remain together as they segregate to progeny they are said to be _____.
Linked;
Recombination frequency between genes is proportional to the distance_____.
between loci
How are recombinant type and parental type progeny identified?
The parental types will always be the two most numerous classes. The recombinant type progeny will be the two least abundant classes.
How can the progeny numbers indicate whether the genes are linked or not?
If the number of progeny types produced are much higher or lower than one another, they are linked.
Parental type progeny
non-recombinant progeny; indicates conformation of alles in the heterozygous parent.
Map Units
% of recombination between two loci= ∑ crossovers btw loci/Total= # Recomb type progeny/(Recomb type progeny + Parental type progeny)
1 Map Unit= __%
1%
What is the maximum number of map units that can be demonstrated between genes?
50; if the distance is greater than 50 MU there is an equal chance of having an equal or odd number of crossovers between the loci, so there is the same chance of producing recombinant or parental genotypes.
Genes that are 50 MU apart or greater are _____, while if they are less that 50 MU they are _____.
not linked, linked
For a mapping problem a parent _____ for two loci will always be crossed with a _____ recessive parent for both loci.
heterozygous, homozygous
If one class of the parental type progeny is dominant phenotype for both loci, and the other class is recessive for both, then the heterozygous parent was in the ____ conformation.
cis
If both classes of parental type progeny were dominant for one loci and recessive for the other, then the heterozygous parent was in the ____ conformation.
trans