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46 Cards in this Set
- Front
- Back
what is a trace element and function as cofactor for enzymes |
selenium |
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glutathione peroxidase GPx iodothyronine deidinase IDI |
selenium |
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what are the symptoms in Se deficiency in animal |
white muscle disease in sheep unsteady gate and arched back |
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deficiency in human |
in some area in china- keshan diease- enlargement of heart, loss of flexibility (cardiomyopathy) - low Se content in soils |
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is there Se deficiency disease in here? does it particially assocaited with cancer |
no yes |
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explain the fuction of selenium |
free radical attack, fatty acid peroxides cause damage, so GSH + Se to GSSG to fatty alcohols then harmless catabolism
GPx helps arrest lipid peroxidation |
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what are the other function of selenium |
IDI is controls the thyroid funciton, T4 to T3 thioredoxin reductase 25 selenoproteins in mammals |
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zinc deficiency |
- stunted growth i children - decreased taste sensation - imparied imune funcion
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severe deficiency |
- dwrfism - delayed sexual maturation - hypopigmented hair |
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human in zinc deficiency first reported in egypt |
diets low in meat, staple based on beans, unleaved bread, other wholegrain foods, high in fibre and ohytate |
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causes of zinc deficiency |
- decreased intake, absorption or increase intake of inhibitor - increased losses - votmit, poo
increased- requirement- growth, pregnancy, lactation |
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zinc intake enhancers |
animal protein organic acids |
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zinc inhibitors |
phytate calcium iron copper oxylate (spinitch, chocolate) |
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zinc intake requirement: 8, 18 hre: 15.2, 10.2 |
sufficient |
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food rich in zinc |
oysters red meat chickn thigh sole |
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what are functions of zinc |
regulation protein and nucleic acid metabolism lipid and carb metabolism interactions with hormones growth and reproducton immune function T cells appetite- taste acuity,night vision vitamin A metabolism |
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RDI for zinc n intake |
60-70 30-60 |
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good source for selenium |
high: fish, brazil nuts, liver and kidney
medium poultry/eggs, other meat
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history of goitre post-re-emergence of mild iodine deficiency |
iodine |
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mild and moderate ID |
smaller than 100 50 |
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reasons for reduction in iodine status |
- reduction in use idophors in dairy industry - lower intake of iodised salt - decreased use of discretionary (salt) - use of non-iodised forms: rock salt |
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what are some IDD? |
hypothyroidism <100 goiter <50 imparied mental function <50 retarded physical develpment and abortion stillbirths, congenital abnormalities <25 cretinism <25 |
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mandatory iodine fortification |
iodine salt in bread |
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what deficiency is most common around the world |
roni |
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shuttle between ferrous to ferric forms also assist many enymes |
iron |
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RDI for iron |
8, 18 1% males and 26% females have inadequate intakes |
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what are the supply for iron |
- amount eaten haem vs non haem promoters andinhibitors in diet |
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what are the requirements of iron |
absortion higher if sttus low menstration growth, regnancy an lactation presence of infections |
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animal flesh from plants |
- provide haem and non-haem - non haem |
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intake of haem and non haem |
10-15 non- 85-90 |
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of absorption |
haem: 25-35 non- haem: 2-10 |
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ron promoters and inhibitors |
promoters: vitamin C meat fish an protein taken at the same time as non-heme iron
inhibitors phytates coffee and tea EDTA calcium, vinc and manganese |
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absorption higher if status low |
cool during life when you are pregnant or groth spurt you need iron |
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iron deficiency severe |
low stores and anaemic |
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functions of vitamin A |
- functio in vision - integrity of epithelial cells - embryonic development - maintnace of immune function
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what is vitamin A deficiency called |
xerophthalmia |
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what are the components and process of itamin A formation cis- trans |
opsin and 11-cis retinal= rhodopsin change in shape leads ot nerves impulse |
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two types of vitamin A |
preformed retinol provitamin A carotenoids |
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beta carotene dioxygenase- 2 retinols
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yeah
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vitamin D process |
7 dehydrocholesterl D3 dietary intake (both to liver) 25 D3 to kidneys form 1,25 dihydroxyvitamin D3
this maintain calcium balance in the body |
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vitamin D deficiency in adults and chldren? |
osteomalacia ricket |
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people with fat malabsorption |
also leads to deficiency, risky |
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source for vitamin D |
oily fish and egg yolk mushrooms that is exposed to the sun
and vitamin D is permitted to be added to diary product
analogues derived fromlegumes and cereals
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have you have too much |
yes, hypercalcaemia |
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main source from vitamin E (tocopherol) |
oil from plants and animal food- fatty tissues and the function is maintaencance of membrne integrity deficiency is rare |
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what does part of coensyme thaimin pyrophosphate does |
assist in energy metabolism of all cells situated on the membrane o nerve cells rapid turn over limited storage.
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