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52 Cards in this Set

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In the case of the Larval tunicates when they mature into addults what is the purpose of sitting on a fucking rock?
To show that in order to move we need nervous systems, if we didn't we could just digest our nervous systems as they require so much energy in order to function properly
The areas of the brain which focus on attention
The right frontal area, and the right parietal areas
Can't pay attention to everything focus on things that you need to and ignore everything else in order to accomplish objective.
How does the nervous system prepare the body for movement?
It plans movement in terms of objectives or goals, not aware of the effector to accomplish the task.
When the nervious system plans movement in terms of goals there are many difficulties that arise. The lecture talks about maps as one problem, what is the underlining problem with maps?
There is a coordinate system transformation of 3D to 2d that needs to be accounted for.
Mercador vs Gnomonic projections
Gnomonic are centered around the North Pole, while Mercador is just centered around the equator.
What must the brain do in order for us to move to a point in the real world?
It must convert joint coordinates into cartesian coordinates. It is non linearity is like a map.
Degrees of freedom
The number of independent pieces of info that go into the estimate of a parameter. Go up can't go down, up/down is one df.
What is necessary in order for you to know where your body goes, position wise.
Degrees of freedom, and spacial perception.
How many degrees of freedom :
Shoulders
Elbows
Wrist
Fingers
4
2
2
2 (not moving all)
There are 10 degrees of freedom in your arms, and there is only the x y z axis in the real 3D world, how does yoru body compensate?
IT ignores many degrees of freedom in order to accomplish the movement goal.
While the problem to convert joint movement and degrees of freedom to the 3D coordinate system determination by effecftors, there is some advanatage of the excess degrees of freedom. What is it?
That we are more adaptive to overcome obstacles that we encounter.
When reaching for a ball, your back and leg muscles contract due to what....
adjustments of center of gravity.
What is involved in catching a ball
5 steps, one has 2 parts.
see ball follow with eyes
prepare to make movements
adjust your posture before making the movement
Execute the movement by creating a signal, and keeping track of the movement trajectory using sensory signals from your msucles and joints (proprioception)
catch it.
When we speak of movement being a parrallel proceess what do we mean by this?
That it happens at several places all at once..ie. primary motor cortex, supplementary motor cortex, Premotor cortex ect Basal ganglia and cerebellum
When we speak of the committe decision of movement what are we refering too.
We speak of movement involving most of the brain, and how it is a parrallel process that envelops many of our body's brain and energy.
Because of the enormous amounts of sensory input caused by movmeent the brain makes up a model. What is the purpose of this?
To better focus, the model of sensory signals it expects from a particular movement is ignored. The brain is then interested in unexpected sensory signals.
Why does kicking a ball and getting a twitch feel so different.
The ball is anticipated, yet getting a twitch is not and therefore the Nervous system focuses more on it.
J.R.Flanagan Prediction turns motor commands into
expected consequences.
3 categories of movement
Reflexes
Rhythmic motor patterns
voluntary movements
Reflexes
involuntary, coordinated patterns of mucle contraction and relaxation elicited by peripheral stimuli.
Several activities that rhythmic neural circuits, central pattern generators produce?
Repetitive patterns of movements like jerking off and walking or running ect.
What is the smallest unit the nervous system can activate with respect to the muscles? And what is that defined as?
The motor unit which is one motoneuron and all the muscle fibers that it innervates
How many alpha motoneurons doesw each muscle fiber receive input from?
1
How many muslce fibers make up each muscle?
thousands.
All the alpha motoneurons that innervate a muscle, that is made up of thousands of muscle fibers is called>>>
Motor neuron pool.
Alpha motorneurons that innervate the arms and shoulders are located:
in the ventral horn of cervical enlargement c3-t1
Alpha motorneurons that innervate the legs are... located...
in L1-S3 in the ventral horn of the lumbar enlargement
Describe from the presynaptic terminal of the NM to the contraction of the individual muscle fibers, how a contraction does its thing.
Depolarization hits and ACh is released binding to ACh receptors in the muscle(post syn) cell allowing Na+ influx K+ Efflux and depolarization occurs.
AChase removes ACh from synaptic cleft.
AP in muscle cell propagates down T-Tubule hits sarcoplasmic reticulum that releases Ca+2 that bind to troponin causing conformational changes.
This moves the tropomyosin binding sites over allowing myosin heads to bind to them.
Myosin heads disengage and uncock converting ATP to ADP a myosin ATPAse.
The act of contracting a muscle continues as long as there is Ca++ pressent, how does muscle relaxation occur?
The sarcoplasmic reticulum uses an ATP driven pump, where the absence of Ca+2 causes troponin to recover the tropomyosin binding sites.
Sarcomere
The fundamental unit of muscle fiber contraction
what is in...(at relaxation)
I - Band
H Zone
A Band
I - actin
H only myosin
A band actin and myosin
Rigor mortis
Body dead, no atp, Ca++ leaks out, and Actin myosin bond and don't break because of the lack of ATP
Muscle twitch
The activation of a muscle fiber by a single firing of a motor neuron.
What needs to happen in order for tetanus to happen?
The frequency of AP must haeppen fast enough it must reach fusion frequency.
How do we look at/study twitches,
Theire size and speed
size in gms of force and speed in time to peak in m/s
When a muscle contracts the force it generates at fusion frequency is considered.
Maximum force.
Fatigability
How long a motorunit maintain its max force with fusions frequency stimulation.
What are the 3 types of motor units
Slow type I
Fast fatigue resistant Type II B
Fast Fatigable Type II A
Which muscle units have high myosin atpase activity?
Fast ones II a and II b
Which muscle units have many mitochondria
Slow and IIB fast ones.
Which muscle units have high muscle fibers diamater and rate of fatique?
IIa
Which muscle units have big motor neurons
Fast IIa
What type of energy does Tyupe IIa Fast muscle fibers use?
Glycolytic energy
What type of energy does the Slow and Fast Type IIb use?
THey use oxidative with lots of mitochondria aerobic respiration.
When running a marathon, what happesn to your motor units, the innervations?
The normal innervation of fast will switch to slow for endurance.
How is gene expression linked to muscles and their innervations?
Neural activity of motorneurons can change the gene expression of muscles, also factors released by the muscles can affect the expression of motorneuron genes!
Size of AP for
FR
FF
Slow
Slow has small ones,
then FR
then FF increasing in size.
What is the size principle
That the nervous system recruits motor neurons in order of theire size, slow > FR> FF
Why do small motorneurons produce less force than bigger motorneurons?
Because small ones innervate fewer muscle fibers and thus produce less force compared to larger ones.
The size princple when recruiting neurons is because of Ohms law.. Please explain how this is so.
Because the input injected to all of the motoneurons have the same strength, small motoneurons have higher input resistance than larger motoneurons, and therefore produce a larger voltage change. This large voltage change allows them to be active first as their epsps are higher because of the voltage.
What dos uniform synaptic input garuntee?
That motoneurons will be recruited from small to large because smaller have more resistence and thus more EPSPs.
What is the advantage of size principle?
That there will be proportional control when using muscles, the force generated by each recruited motor units is proportional to the current force.