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45 Cards in this Set

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Sickle Cell Anemia
Organ: Red blood cells

Defect/Mutation: Defective hemoglobin
Diabetes (1)
Organ: Pancreas

Defect/Mutation: Insulin Production
Cystic fibrosis
Organ: Lungs

Defect/Mutation: CF protein/salt transport
Eukaryotic cells
"True" nucleus with DNA in chromosomes & nucleus membrane

Animals, plants, protozoa

Organelles: Nucleus, Mitochondra, Chloroplasts, Flagella, Lysosomes, Golgi, E.R., vesicles
Procayotic cells
Bacteria

No "true" nucleus

Naked DNA not inclosed in membrane. No mitosis meiosis

No organelles "bounded" by membrane
Covalent Bond
Strong

A sharing of a pair of electrons by two atoms
Hydrogen Atom
drawing
H2: Hydrogen (gas) molecules
drawing
H2 gas
drawing
Oxygen
drawing
Water is polar
Oxygen atoms have a strong (+) nucleus=more electroneg. (attraction) than hydrogen

In water, oxygen atoms pull shares electrons toward them

Results in a partial neg charge on O atom, and partial pos charge on hydro. atom
Ionic Bond
One atom is much more electronegative (attractive) than another, may strip off an electron outer orbitals = 8

Chargen atoms/molecules =IONS

Attraction between oppisitely changes atoms (or molecules) STRONG

Ions attract to =IONIC BOND
Ionic Bond
DRAWING
Hydrogen Bonds:
The attractive force between a (slightly) positive H atom of one molecule, and a (slightly) negative atom (weak, non-covaltent)
Hydrophillic
water loving

Polar molecules: Unequal charge H-bonds with water

Examples: water, sugars, DNA & RNA, most proteins

Charged substance: Bonds with water. Includes: proteins, dan, minerals potassium, chloride, iron, magnesium

Dissolve in water

Found inside: cell cytoplasm, nucleus, mitochondria, E.R., lysosomes, food vacuoles, golgi
Hydrophobic
water fearing

Non-polar/uncharged molecules: uncharged, dont form H-bonds, fats, oils, waxes

Dissolve in organis non polar solvents: gas, benzene, chloroform, methanal, accetone

Found in membranes of: cell, nucleus, mitochondria, E.R., lysosomes, food vacs, golgi
In membranes:
hydrophobic layer

Barrier to movement of polar molecules (water, sugars, proteins, DNA, RNA, vitamins)
Inside cellular compartments:
Hydrophillic

Contains polar molecules (sugars, proteins, DNA, vitamins...dissolved water)
Compartmentalization:
Cells are divided into compartments

The walls of the compartments are membrane

Compartments allow cells to seperate different molecules & different functions
Carbohydrates
C,H,O

Biologcal fuels-burned for energy
*Movement
*Biosynthesis/growth
*Active transport, moving substances across membranes
Monosaccharides
*Glucose
*Fructose
*Galactose
Disaccharides
*Sucrose (fructose-glucose)
*Lactose (galactose-glucose)
*Maltose (glucose-glucose)
Polysaccharides
*Starch
*Cellulose
*Glycogen
Glusoce

(definition, symbol)
The basic sugar of cells

C6H12O6

Forms a ring shape
Starch formula:
(photosynthesis)
E (energy) + CO2 + H20---> sugars (carbs) + O2
Starch formula:
(metabolism)
sugars(carbs) + O2--> CO2 + H2O + E
Glycogen:
*Glucose
*Glucagon
Polysaccharide
*monosacharides
*protein, hormone5
Hyperglycemia:
High blood glucose levels
Hypoglycemia:
Low Blood glucose levels
Hormone:
Substance made by cells which travels through blood to reach target cells and trigger those cells to some action
Hormone examples
Insulin, pancreas, target most cells, take up glucose & convert to glycogen

Glucagon: Pancreas, most cels, convert glycogen back to glucose

Adrnaline, adrenal glands, muscle, liver, heart, blood vessels
Insulin with diabetes:
Weight loss occurs due to insulin lowering blood glucose trying to get into cell. Thus cell does not get nutrients and dies, almost like you arent eating any sugar.
Lipids (types)
Sterols: cholesterol, steroids, estrogen, progesteron, testosterone

Fats: saturated/ unsat. fatty acids

Phospholipids: lipids with phosphate
Lipids:
Provide energy for animals

Principle component of membranes
Major component of membranes:
LIPIDS!
Lipid catagories:
Sterols
*Fatty acids
*Phospholipids
Type of sterols:
Shape:
Cholesterol
*Cortisone
*Estrogen
*Progesterone
*Testosterone

*3 hexagons, home plate
Glycerol Drawing:
Drawing
Fatty Acid:
type of fat, a lipid with a long chain hydrocarbon with "COOH" at one end
Glycerol:
not a lipid but "backbone" of fats known at triglycerides
Tryiglyceride:
a type of fat, a lipid with three fatty acids attached to a gycerol backbone
Phospholipid:
a lipid containing a phosphate
Phospholipid chem drawing:
Drawing
Phospholipid structure: (phillic head, phobic tails)
drawing
Liposomes:
designed for delivery of drugs or dna directly into cells