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65 Cards in this Set
- Front
- Back
B-lymphocytes release _____? What type of immunity are they?
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Antibodies; they don't kill bacteria; HUMORAL IMMUNITY
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T-lymphocytes release _____? What type of immunity are they?
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Perforin molecules which signal the cell to go into apoptosis; CELL MEDIATED IMMUNITY
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Antibodies are _____ but Antigens are _____
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Antibodies are good but Antigens are bad
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What is clonal selection?
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B-cell that recognizes divisions because making clone
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How do you join base pairs?
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sticky ends and DNA ligase
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RFLP = ?
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Restriction Fragment Length Polymorphism (used for fingerprinting and comparing genomes)
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What does the homeobox do?
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Regulates embryo development; hox genes
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What is an episome?
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a type of plasmid that can also integrate into the host genome through the DNA genome
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Macromolecules are synthesized through what kind of reactions? What is the other kind of reaction?
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Dehydration (synthesis); hydrolysis (breaking apart)
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Viruses differ from all other living things in that (2 ways)?
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(1) Viruses are not comprised of cells and (2) they possess either DNA or RNA
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What must all living cells be able to synthesize as a source of chemical energy?
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ATP (Adenosine Tri Phosphate)
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What are the 3 types of macromolecules and their building blocks, and which is most abundant in all cells?
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3 types: Carbohydrates (monosaccharides), Proteins (amino acids), Nucleic Acids (nucleotides); Most abundant = Proteins
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What is one kind of human cell that cannot divide even though it is living
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haploid
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What property of R groups in amino acids help make proteins soluble in the fluid region of membranes
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polar and charged
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in DNA, adenine is paired with ?
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adenine - thymine
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In DNA, guanine is paired with ?
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In DNA, guanine is paired with cytosine
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In RNA, adenine binds with ?
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In RNA, adenine binds with uracil (only found in RNA!)
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Why do most proteins possess a quarternary structure?
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Most proteins possess a quaternary structure because they contain more than one polypeptide (terciary structure is only 1 polypeptide)
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What is chromatin comprised of?
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Chromatin is comprised of histones and DNA
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What charge does DNA have?
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negative (DNA)
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To neutralize the charge on DNA, what must the charge of histones be?
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positive (histones)
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If something is acidic, what is it's charge? Basic?
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Acidic - negative; Basic - positive
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If a tripeptide has 2 acidic R groups and 1 basic R group, what is the net charge?
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1- is the net charge: (2-) + (1+) = 1-
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What polysaccharides are comprised of glucose?
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starch, cellulose, and glycogen are polysaccharides that are comprised of glucose
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WHat holds DNA's double helix together?
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Hydrogen bonds joining the bases hold DNA strands together
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What is the sugar in DNA called?
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deoxyribose
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What is the sugar in RNA called?
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ribose
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What is the site of protein synthesis in prokaryotes?
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ribosome
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The mitochondria is an organelle which contains?
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Organelle - contains cytochromes and the electron transport chain (ETC)
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What does the golgi apparatus do?
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Golgi apparatus - traffic cop; modifies proteins chemically to help direct their final location
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What do lysosomes do?
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Their enzymes break down old denatured proteins
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What does the plastid do?
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the plastid contains chlorophyll and carries out photosynthesis
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Describe ROUGH Endoplasmic Reticulum ?
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Rough ER: intracellular membrane network with ribosomes attached
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Describe SMOOTH Endoplasmic Reticulum?
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Smooth ER: intracellular membrane network with NO ribosomes and synthesizes lipids
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What does cholesterol do?
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Cholesterol affects the fluidity of biological membranes and is needed for the synthesis of steroids
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Which chemical is the major component of all biological membranes?
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phosphate
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Draw a plasma membrane!
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oooo(~~~)oooo
!!!!(~~~)!!!! <-- hydrophobic tails ¡¡¡¡(~~~)¡¡¡¡ oooo(~~~)oooo <--hydrophilic heads |
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Receptor mediated endocytosis does what?
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Receptor mediated endocytosis is a specific type of transport what cause the genetic disease hypercholesterolemia
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In what ways are living cells able to drive reactions that require energy?
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1. Increase reactants at the site
2. Decrease the products at the site 3. Use a coupling reaction to create an exergonic reaction at the site |
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What does activation energy do, how does it affect the substrate?
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The enzyme speeds up biochemical reactions by lowering the activation energy of the substrate
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How does the enzyme catalase catalyze the reaction?
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It affects the rate in both directions
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Glycolysis is the anaerobic oxidation of ______ to ______ while the coenzyme _____ gets _________
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Glycolysis is the anaerobic oxidation of glucose to pyruvate while the coenzyme NAD+ gets reduced
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What is fermentation?
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Fermentation is the reduction of pyruvate to lactate or some other organic molecule
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What happens to NADH and where does it come from?
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During fermentation, the coenzyme NADH is OXIDIZED; it is derived from the vitamin NIACIN
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Glycolysis produces how many net moles of ATP per mole of glucose? (? ATP = 1 glucose)
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Glycolysis: 2 ATP = 1 glucose
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How many moles of ATP are produced by fermentation per mol of pyruvate?
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Fermentation: 0 ATP = 1 pyruvate
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Where is the Krebs cycle located?
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Krebs cycle is in the MATRIX
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Where are the enzymes for glycolysis located?
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glycolysis is in the cytosol
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Krebs cycle produces how many net moles of ATP per mole of pyruvate that is oxidized? How much per glucose?
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Krebs cycle: 1 ATP = 1 pyruvate = (2 ATP = 1 glucose)
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Mitochondria produces how many net moles of ATP per mole of glucose?
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Mitochondria: 32 ATP = 1 glucose
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Glucose is oxidized into what?
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H20 and CO2
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What do redox reactions create?
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Redox reations --> proton gradient
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The proton gradient synthesizes ______ through ______ and _______?
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The proton gradient synthesizes ATP through mitochondria and chloroplasts?
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THe synthesis of ATP is catalyzed by what enzyme?
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ATP Synthase?
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What are cytochromes?
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Cytochromes: iron atoms (ions) present in redox catalysts
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Where does ATP synthase occur?
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mitochondria
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What inhibits ATP synthesis in mitochondria by combining with cytochromes?
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Cyanide
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Where is the ETC located?
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ETC: innermembrane of the mitochondria
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Where do homologous duplicated chromosomes line up along one axis of the cell?
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Mitosis I
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What happens in Prophase I?
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Prophase I: Recombination occurs between homologous chromosomes
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What is the probability that 3 of your chromosomes are all derived from your mother's father?
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P = (1/2)^3
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If chromosomes fail to segregate normally, what stage would this occur during?
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Meosis I
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What is nondisjunction?
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When chromosomes fail to segregate normally
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What is a chromosome abnormality that increases markedly as a function of mother's age?
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Down Syndrome
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What is an example of a sex-linked recessive trait?
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Hemophilia (is only on the x-chromosome)
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