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5 Cards in this Set
- Front
- Back
In the presence of oxygen and in the absence of ADP, what occurs if the uncoupler 2,4-dinitrophenol is added to a suspension of normal mitochondria five minutes after an oxidizable substrate has been added? |
Oxidation of the substrate does not occur until the 2,4-dinitrophenol is added. Afterward, oxidation proceeds rapidly until all of the substrate is consumed. |
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In the presence of an uncoupler, more substrate can be oxidized. |
True |
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Uncouplers are compounds that inhibit the phosphorylation of ADP |
without affecting electron transport. |
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Uncoupling agents can work by disrupting the flow of protons during ATP synthesis. |
True |
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Uncoupling in mitochondria refers to: |
Stopping ATP synthesis but not stopping electron flow. |