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52 Cards in this Set

  • Front
  • Back

Prokaryote genetics

single circular molecule (nucleoid)

Cytoplasm
fills cell interior
Plasma membrane
encloses the cell
Schleiden & Schwann
proposed the Cell Theory
Robert Hooke
discovered cells in 1665
Cell Theory
All organisms composed of cells, cells are smallest living units of organisms, cells arise only by division of existing cell
Resolution
minimum distance 2 pts can be apart and still be distinguishable
Light microscopes
use magnifying lenses with visible light, resolve structures 200 nm apart
Electron microscopes
use beam of electrons, resolve structures .2 nm apart
Transmission electron microscope
good 2D images
Scanning electron microscope
produce good 3D images
Nucleoid
DNA in prokaryotic cells
Cytoplasm
surrounded by plasma membrane and encased in cell wall
Eukaryotic cell
characterized by compartamentalization by endomembrane system, membrane-bound organelles
Nucleus
inheritance, RNA production, contains chromatin (nucleosomes), nucleolus
Mitochondrion
energy production
Endoplasmic reticulum
protein and lipid production
Golgi apparatus
glycosylation, secretion
Lysosomes
degradation
Peroxisomes
degradation, detoxification
Nucleolus
ribosomal RNA assembly >> which leave through nuclear pores
Chromosomes
humans have 23 pairs, each chromosome has hundreds of genes
Eukaryotic genetics
linear chromosomes, strands of chromatin, DNA wrapped around histones forms nucleosomes
Endomembrane system
divides cell into compartments in which diff cellular functions occur, includes ER, Golgi, lysosomes
Smooth ER
important in lipid synthesis
Rough ER
contains ribosomes, site of protein synthesis
Ribosomes
made of ribosomal RNA and proteins, assembled in nucleoli, site of protein synthesis
Golgi
collection of golgi bodies that collect, package, and distribute molecules synthesized and utilized at diff locations, produces sugars and forms glycoproteins, glycolipids, final protein folding, stores secreted material
Cis side
receiving side of golgi, vesicles enter here
Trans side
shipping side of golgi
Vesicles
part of endomembrane system, membrane-bound, incl lysosomes, microbodies
Lysosomes
membrane-bound digestive vesicles, arise from golgi, enzymes catalyze breakdown of macromolecules, destroy cells, foreign matter engulfed by phagocytosis
Microbodies
enzyme-bearing, membrane-enclosed vesicles
Peroxisomes
contain enzymes that catalyze removal of electrons, associated hydrogen atoms, degradation & detoxification, protection from toxin damage
Autophagy
how cells bring in material
Phagocytosis
cells bring in insoluble, solid material, “cell eating”
Pinosytosis
cells bring in soluble, liquid material, “cell drinking”
Mitochondria
bound by exterior, interior membranes, interior partitioned by cristae, generates ATP through oxidative phosphorylation, has its own circular DNA, maternally inherited, several 100 per cell
Chloroplasts
internal stacked grana, which contain thylakoids, used for photosynthesis, present in plants and some other eukaryotes
Endosymbiotic theory
engulfed eukaryotes provided hosts with metabolic advantages, evolved
Cytoskeleton
fibers, filaments, associated proteins that maintain cell shape, connect cells, transport organelles, small molecules, provide cell motility, move chromosomes, and compose cilia
Actin filaments
smallest part of cytoskeleton, 7 nm diameter, made of actin molecules, used in contraction, crawling, pinching
Microtubules
biggest filament, 25 nm in diameter, a & B tubulin dimers, used in organization of cytoplasm, mvmt of cargo
Intermediate filaments
8-10 nm diameter, made of protein dimers, stable, mechanical strength of cell
Centrosomes
region surrounding centrioles in animal cells, microtubule-organizing center, plants and fungi lack these
Centrioles
cylindrical organelle near nucleus, manufactures fibers
Flagella, cilia makeup
9+2 arrangement of microtubules
Kinesin
motor protein moves vesicles towards periphery of cell
Dynein
moves cargo or vesicles toward center of cell
Cellulose cell wall
found in plant cells, provide rigidity and structure
Integrins
proteins that link cytoskeleton and ECM proteins in animal cells
Extracellular matrix

animal cells lack cell walls, so they secrete mixture of glycoproteins into surroundings, esp collagen, to form protective layer over cell surface, linked to cytoskeleton by integrins