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23 Cards in this Set
- Front
- Back
define: Epidemiology
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a branch of medical science that deals with the incidence, distribution, and control of disease in a population.
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Define: Incidence and Prevalence
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Incidence: The number of new cases contracted in a population during a specific period of time.
Prevalence: Total number of people infected in a population during any given time |
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Define: Morbidity vs Mortality Rates
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Morbidity= # of ppl affected in relation to the total number of ppl in a population.
Mortality: Number of deaths during a specific period in relation to the total population. |
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Define: Endemic Disease
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present continually but the number of cases and severity remain too low to constitute a problem (what does graph look like vs epidemic? Slide 7 CH15)
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Define: Epidemic and Pandemic
Also: 2 Examples of epidemics given |
Epidemic= High number of cases and severe disease.
Examples are diphtheria in USSR after its split (1989-1997) and St, Louis encephalitis. Pandemic- An epidemic that spreads worldwide |
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Sporadic Disease
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Occurs in a random and unpredictable manner, involving several isolated cases that pose no great threat to the population as a whole.
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Epidemiological Studies: Descriptive Studies
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Concerned about disease spread and records:
1) Number of cases 2) Segments of population affected 3) Locations and time period of cases. Additionally age, gender, race, marital, and economic status are recorded. |
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Common-Source Outbreaks and Propagated Epidemics
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Common Source- all cases occur within a short time after exposure and then stop
Propagated Epidemics- New cases are continually seen (Graph for both of these looks like) |
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John Snow
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Essentially began the field of epidemiology through his study of cholera originating from a water pump on a street in London.
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Analytic Studies of Epidemiology
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Focus on cause and effect relationship.
1) Retrospective- past data (ex: Smoking and cancer) 2) Prospective- As epidemic spreads (ex: hantavirus oubreak in 1993 in US) |
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Experimental Studies
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designs experiments to test a hypothesis. Polio vaccine was done in this was (placebo and no placebo group)
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Reservoirs of Infection
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1) Human- Carriers (harbor disease w/o any symptoms)
2 types: Chronic and Intermittent 2) Animal-Monkeys are most major. They carry malaria yellow fever etc 3) Nonliving-Soil and water. Ex: C. tetani, C. Botulinum, Salmonella |
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Zoonoses
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Diseases that can be transmitted (under nat. conditions) to humans from other vertebrates.
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Portals of Entry
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Ear, eye, nose, mouth, mammary glands, urethra, vagina, anus, placenta, broken skin, seminal vesicles.
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Modes of Transmission: Contact
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1) Direct- ex: syphilis, staph, warts, most STD's
2) Indirect- Tetanus, common cold, enterovirus 3) Droplets- Common cold, influenza, measles, Q fever, pneumonia, whooping cough |
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Modes of Transmission: Vehicle
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1) Waterborne- Cholera, shigelliosis, Camphylobacter
2) Airborne- Chicken Pox, tuberculosis 3) Foodborne- botulinum toxin |
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Modes of Transmission: Vector
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1) Mechanical- on insect bodies
ex: E-coli, diarrhea, salmonella 2) Biological: Plaque, malaria, yellow fever etc |
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Herd Immunity
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As the number of individuals who are immune to a disease increases, the likelihood that they will come into contact with the disease drops
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CDC slide
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States that measles has decreased by 55% in 1997
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Nosocomial Infections (3 Types)
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Acquired in a hospital or other medical facility:
1) Exogenous Infections (environment) 2) Endogenous Infections (opportunists) |
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Common caussative agents of nosocomial infections (4)
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1) Escherichia Coli
2) Staphylococcus Aureus 3) Streptococcus 4) Pseudomonas/ Klebsiella (Tied) |
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Relative Frequencies of Sites of Nosocomial Infections
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1) Urinary Tract
2) Surgical Wounds 3) Respiratory Tract |
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Bioterrorism Agents
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1) Anthrax(1-5d)
2) Botulism(1-5d) 3)Plague (2-3d) 4) Smallpox 5)Tularemia (7-17d) 6) Ebola Virus (14d) 7) Marburg- Hemorrhagic Fever (8d) |