Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
|
hooke
|
credited with discovery of cells, cork
|
|
|
leeuwenhoek
|
sees "animalcules", first to see living cells and describe bacteria
|
|
|
cell theory
|
schleiden, schwann, virchow, dutrochet
|
|
|
hans driesch
|
1891, sea urchin development, embryonic cells sep after first division and each undrestands no longer attached to neighbor and reprograms self to give rise to complete embryo (SELF-REGULATION)
|
|
|
eduard and hans buchner
|
1890s, showed presence of living yeast cells was not needed for fermentation and called the catalysts enzymes
|
|
|
sumner
|
1920's, crystallized enzymatic activity from beans, substance was shown to be a protein--> now know most enzymes are proteins
|
|
|
overton
|
1890's- proof of non-polar nature of membrane (used plant rot cells, showed they rapidly take up non-polar, lipid-soluble compounds --> proposed outer boundary of the cell was non-polar)
|
|
|
gorter and grendel
|
1926- proof of bilayer (known # of blood cells, measure surface area in microscope and then extract lipids and float on water and get 2x the area)
--they proposed nonpolar chains interact and polar head groups face h20 |
|
|
1950's lipid bilayer proof
|
transmission electron microscope confirms lipid bilayer, showed trilaminar structure with dark outer layers and clear center
|
|
|
davson and danielli
|
became clear that polar material was moving across membrane --> pore theory. proposed not simply lipids but proteins
then freeze fracture electron microscopy we see proteins embedded in the membrane |
|
|
singer and nicolson
|
1970s, fluid mosaic model, protein "ships" in a lipid "sea", very dyamic structure
|
|
|
frye and edidin
|
1970, used cell fusion mediated by a virus to show that proteins move laterally thru the membrane
|
|
|
RBC plasma membrane: band 3
|
carries CO2 from blood to lungs, passive exhcnage of hco3 and cl
|
|
|
RBC plasma membrane: glycophorin A
|
negative charge on sugars, RBC repel eachother, don't clump
|
|
|
spectrin, ankryrin, actin
|
maintain strength and shape
|
