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13 Cards in this Set

  • Front
  • Back
what are MHC self antigens?
Major Histocompatability Complex antigens identify with our own cells
what's the role of MHC
to help T cells recognize that an antigen is foreign, not self
explain the role of T cell receptors
recognize and bind to specific foreign antigen fragments that are presented in antigen MHC complexes
Explain the role of B cell receptors
bind to antigen in extra cellular fluid
how does cell mediated response activate
begins with activation of T cell by specific antigen
what's the role of helper T cells?
secrete several cytokines, interleukin 2 which acts as a costimulator for other helper T cells, cytotoxic T cells and B cells
What's the role of Cytotoxic T cells
display CD 8 proteins and attack pathogens
What's the role of memory T cells?
recognize original invading antigen, allowing much swifter reaction should the pathogen invade the body at a later date
what's the function of perforin
inserts into the plasma membrane of the target cell and creates channels in the membrane. Extracellular fluid fllows into the target cell and cytolysis occurs
what's the role of interleukin
act as a costimulator for resting helper T cells or cytotoxic T cells and enhances activation and proliferation of T cells, B cells and natural killer cells
what the role of immune surveilance
recognizes a tumor antigen as nonself and destroys any cancer cells carrying that antigen
what are antibodies
proteins that combine specifically with the antigenic determinant on the antigen that triggered its production
how do antibodies help fight infection?
neutralization- bind with toxins to prevent spread

agglutination- bind with foreign cells

amplification- of other immune responses by identification