Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
|
what are MHC self antigens?
|
Major Histocompatability Complex antigens identify with our own cells
|
|
|
what's the role of MHC
|
to help T cells recognize that an antigen is foreign, not self
|
|
|
explain the role of T cell receptors
|
recognize and bind to specific foreign antigen fragments that are presented in antigen MHC complexes
|
|
|
Explain the role of B cell receptors
|
bind to antigen in extra cellular fluid
|
|
|
how does cell mediated response activate
|
begins with activation of T cell by specific antigen
|
|
|
what's the role of helper T cells?
|
secrete several cytokines, interleukin 2 which acts as a costimulator for other helper T cells, cytotoxic T cells and B cells
|
|
|
What's the role of Cytotoxic T cells
|
display CD 8 proteins and attack pathogens
|
|
|
What's the role of memory T cells?
|
recognize original invading antigen, allowing much swifter reaction should the pathogen invade the body at a later date
|
|
|
what's the function of perforin
|
inserts into the plasma membrane of the target cell and creates channels in the membrane. Extracellular fluid fllows into the target cell and cytolysis occurs
|
|
|
what's the role of interleukin
|
act as a costimulator for resting helper T cells or cytotoxic T cells and enhances activation and proliferation of T cells, B cells and natural killer cells
|
|
|
what the role of immune surveilance
|
recognizes a tumor antigen as nonself and destroys any cancer cells carrying that antigen
|
|
|
what are antibodies
|
proteins that combine specifically with the antigenic determinant on the antigen that triggered its production
|
|
|
how do antibodies help fight infection?
|
neutralization- bind with toxins to prevent spread
agglutination- bind with foreign cells amplification- of other immune responses by identification |
