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8 Cards in this Set

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  • Back

Frederick Griffith

Used streptococcus pneumoniae on mice to discover transformation which is change in genotype and phenotype due to assimilation of external DNA by a cell

Hershey and Chase

Used E. coli to discover that DNA functions as genetic material -- DNA is what is on genes, not proteinni

Rosalind Franklin

Saw DNA through X-ray defraction and discovered it is shaped into a double helix

Purines and pyrimidines

Purines: adenine and guanine (longer)


Pyrimidines: thymine and cytosine

Types of replication & the real one

Conservative: the original helix stays together and you just have copies


*Semi-conservative: helix separates and mixes with copies


Dispersive: chunks of old and new stick together

Meselson and Stahl

Used E.coli to discover that DNA replication is semi-conservative

Meselson and Stahl

Used E.coli to discover that DNA replication is semi-conservative

Enzymes associated with cell replication

Topoisomerase, helicase, single-strand binding proteins, primase, RNA primer, DNA pol 3, DNA pol 1, Okazaki fragments, DNA ligase