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54 Cards in this Set

  • Front
  • Back
What are the 5 F risk factors for gallstones?
Female, Fat, Fertile, Forty, Farty
What's your acronym for risk factors for gallstones?
ABCC FFFF III SHORTV
What is ABCC?
-American-Native american
-Biliary stasis
-Chronic hemolysis
-Cirrhosis
What does III stand for?
-Infection
-Ileal resection
-IBD
What does SHORTV stand for?
-Somatostatin therapy
-Hyperlipidemia
-OCPs
-Rapid weightloss
-TPN
-Vagotomy
What are the 3 most common types of gallstones and which is the MOST common?
-Cholesterol stones 75%
-Black pigmented
-Brown pigmented
What factors lead to cholesterol stone formation?
Bile that is supersaturated with cholesterol, and decreased gallbladder emptying
What are black pigmented stones made of and what causes them to form?
Calcium bilirubinate - caused by cirrhosis and hemolysis in a sterile gallbladder
What are brown pigmented stones like in composition and what causes them to form?
-Soft, located in bile ducts
-Formed in infected bile
What is Biliary Colic?
Pain caused by a TRANSIENT obstruction of the cystic duct with a gallstone
What is acute cholecystitis?
Unrelenting pain due to gallbladder inflammation caused by a gallstone obstructing the cystic duct
What % of acute cholecystitis is due to stone vs acalculous?
Stone - 95%
Acalculous - 5%
Where is the pain located in
-Biliary cholic
-Acute cholecystitis
Both - RUQ, epigastric, subscapular
Which biliary pain tends to be poorly vs well-localized?
Biliary cholic - poorly localized

ACC - well localized
What is the duration of pain in
-Biliary cholic
-Acute cholecystitis
BC - transient

ACC - unrelenting
What are some signs/sx of
-Biliary cholic
-Acute cholecystitis
BC - n/v/doubled up

ACC - n/v/ FEVER
What is the hallmark sign in
-Biliary cholic
-Acute cholecystitis
BC - Boas sign

ACC - Murphy's sign
What is Boas sign?
Referred right subscapular pain
What is Murphy's sign?
Inspiratory arrest and sharp pain on palpating the liver when you have the patient inspire
What are 4 bugs that typically cause acute cholecystitis?
-E. coli
-Klebsiella pneumo
-Strep faecalis
-C welchii/perfringens
What lab findings are often seen in Biliary colic?
None
What lab findings are often seen in acute cholecystitis?
-High WBC
-Sl high ALP
-LFTs
-Amylase/T-Bili
What is the treatment for biliary colic?
Lap cholecystectomy
What is the treatment for acute cholecystitis?
-IVF
-NG decompression
-Open or LAP Chole ASAP!!!
What is the initial study of choice for patients with biliary tract disease? Why?
Ultrasound
-May show stones/sludge, thickened walls, and fluid
What are some disadvantages of US for biliary disease?
-Not good for fat people
-Doesnt work for ascites/gas
-Cant see stones in the bile ducts
How useful are abdominal films for gallstones?
10-15% of stones are radioopaque and show up; can't use if pregnant obviously
What are the 2 best ways to visualize gallstones in the biliary duct system?
-ERCP
-PTC
What is ERCP?
Endoscopic Retrograde Cholangiopancreaticography
How is ERCP done?
By injecting contrast into the GI tract, thru the sphincter of oddi, and into the biliary tree
What is a disadvantage of ERCP?
May dmg the sphnicter of oddi, and requires anesthesia
What is PTC?
Percutaneous transhepatic cholangiography
How is PTC done?
By injecting dye through the skin directly into the liver parenchyma
What can be injected intravenously to visualize GB duct obstruction?
HIDA/PRIDA
What is HIDA/PRIDA?
Using radiolabeled Iminodiacetic Acid injected into the bloodstream to see if it entersthe bile ducts and gb
What tells you if there is a cystic duct obstruction on HIDA/PRIDA?
Failure to see the labelled substance enter the gallbladder after 4 hours
What is oral cholecystogram?
Ingestion of an oral contrast agent that concentrates in the gallbladder, then visualized by XRaying the RUQ
Is CT very good for gallbladder and biliary duct disease?
no
What is IV Cholangiography?
IV Injection of Iodine-contrast
What are 2 drawbacks to using IV cholangiography?
-May cause anaphylactic rxn
-Contrast not excreted if the patient has jaundice
If a patient w/ gallstones developed jaundice, tea colored urine and acholic stools, what might you suspect?
Choledocholithiasis
What is choledocholithiasis?
Gallstones that have moved out into the bile duct
What are 6 possible complications of gb stones?
-Choledocholithiasis
-Acute cholecystitis
-Cholangitis
-Gallstone ileus
-Gallstone pancreatitis
-Gallbladder cancer
What is Cholangitis?
Bacterial infection of the biliary tract due to obstruction
What are the triad/pentad in cholangitis?
Charcot's triad
Reynold's pentad
What is Charcot's triad?
Fever/chills
RUQ pain
Jaundice
What is Reynold's pentad?
Charcot's plus AMS/shock
What exactly is Reynold's pentad seen in?
Acute suppurative cholangitis
What labs are elevated in Cholangitis?
-WBC
-T-bili
-ALP
-AST
-ALT
What is the treatment for suppurative cholangitis?
-IVF
-Antibiotics
-Decompression with ERCP, PTC, or T-tube placement
What is Gallstone ileus?
SBO caused by a large gallstone thru the GB, passing to the GI tract via fistula where it gets impacted before the ileocecal valve
How is Gallstone ileus diagnosed? (3 tests)
Abd Xray - air in the biliary tree!!
US - sees the stone
Barium study - biliary-intestinal fistula
What is the treatment for gallstone ileus?
-Celiotomy
-Enterolithotomy
-Cholecystectomy
What is Gallstone Pancreatitis caused by?
Obstruction of the ampulla of vater by a gallstone, or biliary sludge.