Biliary System 2

Front 1

before the Hep B vaccine, ____% of general dentists and ____% of oral surgeons had hep B

Back 1

7-9% and 21%

Front 2

hep b can be contracted from

Back 2

needlesticks, contaminated survfaces, splashes to eye, or oral mucosa, percutaneously thorugh cuts or breaks in skin, contact with infected saliva

Front 3

hep b is ___ times (more/less) infective than HIV

Back 3

50-100 times MORE

Front 4

hep c used to be called

Back 4

hep non-a, non-b

Front 5

hep c is DNA or RNA virus?

Back 5

RNA virus

Front 6

how many people in the us have hep c

Back 6

4 million

Front 7

how is hep c transmitted

Back 7

blood and blood products

Front 8

most peple with hep c infections got it from

Back 8

blood transfusions prior to 1990

Front 9

hep c can be sexually transmitted t/f

Back 9

t

Front 10

what is the leading reason for liver transplants in usa

Back 10

hep c

Front 11

hep b can proceed to chronic infection without an acute stage; hep c can proceed to chronic infection without an acute stage;

Back 11

The first statement is true and the second statement is true

Front 12

evan is a redneck; he is also yellow-bellied

Back 12

The first statement is true and the second statement is false

Front 13

most hep c infecitons become chronic and remaain in a persistent carrier state (t/f, name percentage)

Back 13

true; 85% become chronic

Front 14

hep c can be transmitted via saliva

Back 14

f

Front 15

which is more infectious, hep b or hep c

Back 15

hep b

Front 16

vaccine is available for hep c

Back 16

no, false

Front 17

hep c treatment involves which two drugs

Back 17

interferon and ribaviron

Front 18

most cases of hep c resolve

Back 18

false; 15 percent resolve, most go chronic

Front 19

most cases of chronic hep c form cirrhosis

Back 19

false; 20 percent form cirrousis, 80% stabilize

Front 20

name 4 extra hepatic manifestationso f chronic hep c

Back 20

sjogren's like syndrom (dry eyes, dry mouth); rheumatoid arthritis; lichen planus (skin/mucosa) in 5-10%; Thrombocytopenia purpura

Front 21

hep d is an RNA/DNA/partial RNA virus

Back 21

partial RNA

Front 22

hep d needs which other type of hep to survive

Back 22

hep b; simultaneous infection with acute hep b, or superihnfection with previous chronic hep b

Front 23

hep d transmission can be via

Back 23

blood and sexual

Front 24

hep e is transmitted fecal-orally, hep a is also transmitted fecalorally

Back 24

true;true

Front 25

hep e produces Acute/chronic/both hepatitis

Back 25

acute

Front 26

hep e can cause ________, especially in india, and with pregant people

Back 26

fulminant hepatitis

Front 27

hep e can become chronic; there is no carrier state

Back 27

False (it doesnot beome chronic); true

Front 28

Hep f exists

Back 28

probably not

Front 29

Hep G is common; it is also well understood

Back 29

false; false

Front 30

TTV stands for

Back 30

Transfusion-transmitted Virus

Front 31

long term sequelae to chronic hep b and c can include

Back 31

cirrhosis, increased bleeding tendencies, hepatocelluar carcinoma

Front 32

HBeAg is a marker of

Back 32

infectivity of hep b

Front 33

describe what HBsAg, HBeAg, and anti-HBc levels do in cases of chronic hep b versus resolving hep b

Back 33

chronic - levels remain moderately high; resolving, anti-HBc remains high, but HBsAg and HBeAg (marker of infectivity) die off

Front 34

biliary cirrhosis is more common in

Back 34

women 9:1 ratio women:men

Front 35

biliary cirrhosis affects the

Back 35

ductile system of liver

Front 36

primary billiary cirrhosis is

Back 36

autoimmune disease in which antimitochondrial antibodies are characteristic

Front 37

an autoimmune disease in which the bile ducts are the target, and protal tract granulomas form

Back 37

primary biliary cirrhosis

Front 38

secondary biliary cirrhosis is due to

Back 38

due to longstanding extra-hepatic biliary obstruction, sclerosisng cholagnitis, and tumors of pancreas

Front 39

bile stasis looks like ____ and is common in ____ (disease)

Back 39

yellow green discoeration of the liver; common in secondary biliary cirrhosis

Front 40

alcoholic liver disease

Back 40

steatosis (fatty changes in hepatocytes); focal liver cell necrosis, infiltrates of neutrophils and mallory bodies

Front 41

mallory bodies are

Back 41

intracytoplasmic eosinophillic inclusions

Front 42

steatosis

Back 42

fatty changes in hepatocytes

Front 43

a liver will first suffer from ______ or _______ before it finally ends up cirrhotic from alcoholic liver diesease

Back 43

steatosis or hepatitis

Front 44

hemochromatisis

Back 44

autosomal recessive defect of iron absorption that leads to excess iron accumulation and pigmented micronodular cirrhosis

Front 45

gilbert's disease

Back 45

autosomal dominant, asymptomatic, affects 5% of population, intermittent jaundice, unconjugated hyperbilirubinemia

Front 46

wilson's disease

Back 46

autosomal recessive diesase of copper matabolism resuliting in accumulation of copper and kayser-fleisher rings

Front 47

alpha-1-antitrypsin deficiency

Back 47

one of most common causes of childhood cirrhosis, high mortatlity rate, high rate of liver cancer

Front 48

crigler-najjar

Front 49

dubin-Johnson

Front 50

Rotor syndrome

Front 51

yayser fleisher rings

Back 51

brown ring discoleoration of the iris the is common in wilson's disease (accumulation of copper)

Front 52

is gilbert's disease more common in women or men

Back 52

males

Front 53

Budd-Chiari syndrome

Back 53

thrombosis of/obstruction of the hepatic vein

Front 54

autoimmune hepatitis - how do you treat it?

Back 54

steroids

Front 55

primary biliary cirrhosis

Back 55

autoimmune disease: destruction of intrahepatic bile ducts and progression to cirrhosis, htought to be due to type IV hypersensitivity

Front 56

Primary biliary cirrhosis is autoimmune, but secondary biliary cirrhosis is not autoimmune

Back 56

true; true

Front 57

primary sclerosing cholangitis

Back 57

autoimmune; affects young males (under age 40), usually have underlying bowell disorder; increased incidence of cholangiocarcinoma (10%)

Front 58

hemangioma

Back 58

most common benighn hepatic tumor

Front 59

adenoma

Back 59

benign hepatic tumor associated with oral contraceptife use, almost all in women

Front 60

Metastatic disease in liver

Back 60

malignant tumor of liver; majority of liver malignaccies are metastatic; poor prognosis

Front 61

hepatocellular carcinoma

Back 61

most common primary malignancy; 5:1 males

Front 62

a person with aflatoxin B1 or increased serum levels of alpha-fetoprotein might have

Back 62

hepatocellular carcinoma (most common primary malignancy)

Front 63

cholangeocarcinoma

Back 63

bile duct carcinoma

Front 64

liver fluke infection is associated with

Back 64

cholangiocarcinoma

Front 65

t/f cholahngeocarcinoma is associated with HBC, HBV, and/or cirrhosis

Back 65

f

Front 66

exposure to pvc, thorotrast and arsnec is associated with

Back 66

hemangioscarcoma (a rare and malignant vascular tumor)

Front 67

cholecystitis (acute)

Back 67

inflamation, nausea, upper right quadrant/epigastric pain, might think it is a heart attack

Front 68

cholecystitis (chronic)

Back 68

thinckening of gallbladder wall due to fibrosis, chronic inflamations; frequently complicated by gallstones

Front 69

porcelain gallbladder

Back 69

dystrophic calcification in gallbladder

Front 70

cholelithiasis

Back 70

gallstones - causes irritation of gallbladder

Front 71

gallstones are more common in

Back 71

women 3:1; native americans; over fourty years old, fertile (multiple pregnancies), fat people

Front 72

asian gallstones are primarily made of

Back 72

calcium birubinate mixed with cholesterol

Front 73

in u.s. gallstones are primariliy made of

Back 73

cholesterol

Front 74

adenocarcinoma

Back 74

most common primary tumor of gallbladder - very poor prognosis

Front 75

t/f gallbladder tumors are often benign

Back 75

f