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12 Cards in this Set

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What is the clinical presentation of ascending cholangitis?

Charcot's triad: fever, abdominal pain and jaundice

Imaging appearance of ascending cholangitis?

CT shows hyperenhancement and thickening of the bile duct walls




US may see some debris in the biliary system

Tx for ascending cholangitis?

Conservative with abx and fluids usually.




May need endoscopic biliary intervention if doesn't respond.

What is primary sclerosing cholangitis?

idiopathic inflammation and destruction of bile ducts.

What disease is PSC most commonly associated with?




% of PSC with this disease?

Ulcerative colitis




(75% with PSC have UC; although onlyl 4% with UC have PSC).

What is the imaging appearance of PSC?

- Beaded irregular common bile duct and intrahepatic bile ducts.

What other disease does PSC also look similar to based on the imaging findings?




What's the difference?

HIV cholangiopathy




HIV cholangiopathy more often has papillary stenosis.

Long-term consequences of PSC? (3)

- Cirrhosis


- Cholangiocarcinoma


- Recurrent biliary infections




*x-sectional imaging better at looking for these complications than ERCP

What is primary biliary cirrhosis, how does it differ from PSC, and who does it affect?

Inflammation and destruction of smaller (only intrahepatic) bile ducts than compared with PSC.




Middle aged women. (presents with pruritis)




*can lead to cirrhosis like PSC

AIDS (HIV) cholangiopathy is similar in appearance to primary sclerosing cholangitis. What is the presumed etiology of HIV cholangiopathy?

Biliary infections: CMV and Crytosporidium --> RUQ pain, fever, and elevated LFT's.




*remember it leads to papillary stenosis aka stenosis of the Sphincter of Oddi (in contrast to PSC).

What is the cause of recurrent pyogenic cholangitis?

Clonorchis sinensis (liver fluke) --> pigment stone formation, biliary stasis and cholangitis.




Indiginous to SE Asia (aka Oriental cholangiohepatitis)




*inceased risk cholangiocarcinoma

What is the imaging appearance of recurrent pyogenic cholangitis? (3)

Triad:


- Pneumobilia


- Lamellated bile duct filling defects


- Intra and extrahepatic bile duct dilation and strictures.