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8 Cards in this Set
- Front
- Back
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What does hemoglobin transport?
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h+, co2, and o2
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3 ways co2 is transported in the blood?
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1. h+ binds to heme, hco3- in blood
2. dissolves in plasma 3. directly bind to heme |
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What happens at low pH?
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his is protonated and stabilized the T state, lower affinity
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What is BPG? Where does it bind?
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It's a negatively charged particle, binds to the middle of the 4 subunits, you get stabilized t- state
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describe sickle cell anemia?
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autosomal recessive disorder, caused by glu->val
results in hydrophobic patch polymerization only occurs in the T state |
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muscle structure in decreasing order?
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myofiber-> myofibril-> sarcomere
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what are the components of a sarcomere?
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dark band(thick), light band(thin), myosin, actin, z-disc
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how are the actin binding sites exposed?
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by calcium binding to troponin
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