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14 Cards in this Set

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not given
Treponema pallidum
syphyilis; chancre followed by fever, lethargy, rash (notably also on palms and soled); gummas, degenerative changes in CNS; cardiovascular lesions
relapses caused by surface antigen variation
Borrelia recurrentis
recurrentis--relapsing fever; multiplies by binary fision; arthropod born (ticks and louses);
not given
Borrelia burgdorferi
bull's eye (ECM) 60%; erythema chronicum migrans; late manifestations include arthritis in joints, cardiac, and neurological syndromes
phagocytosed into endothelial cells where they live and replicate; pass from cell to cell
Rickettsia rickettsi
Rocky mountain spotted fever (rash)
not given
Rickettsiae
Scrub fever-- R. akari, R. conori, R. tsutsugumushi; Typhus fever--R. typhii, R. prowazekii; trench fever, Q fever, and Ehrlichiosis caused by other related organisms
adhere to mucosal epithelium via 2-pronged end structure; no antimicrobials available
Mycoplasma
smallestfree living organisms; cause walking pneumonia (M. pneumoniae); spread by aerosol droplets
taken up into endosomes where EB bodies can turn into RB bodies and replicate; secreted (C. pneumoiae and C. trachomatis) or cell is lysed (C. psitacci); C trachomatis transmittable through birth canal
Chlamydia
C. trachomatis is most common sexually transmitted disease; causes sterility in females, trachoma, and lymphogranuloma venerum (LGV)--ulcers on genitalia, red skin,rectal bleeding; conjuctivitis and pneumoniae in newborns
syphyilis; chancre followed by fever, lethargy, rash (notably also on palms and soled); gummas, degenerative changes in CNS; cardiovascular lesions
Treponema pallidum
ID with darkfield microscope, serological testing in secondary stage, FTA-ABS, immunohistochemical, aerobic-anaerobic
recurrentis--relapsing fever; multiplies by binary fision; arthropod born (ticks and louses);
Borrelia recurrentis
G- negative, flexible spiral, Giemsa staining of blood smears
bull's eye (ECM) 60%; erythema chronicum migrans; late manifestations include arthritis in joints, cardiac, and neurological syndromes
Borrelia burgdorferi
G- negative, flexible spiral, serology, IFA, EIA, Western blot conformation, peak levels of IgG take 4-6 months
Rocky mountain spotted fever (rash)
Rickettsia rickettsi
G- short, nonmotile; immunohistological stain of endothelial cells
Scrub fever-- R. akari, R. conori, R. tsutsugumushi; Typhus fever--R. typhii, R. prowazekii; trench fever, Q fever, and Ehrlichiosis caused by other related organisms
Rickettsiae
G- short, nonmotile; immunohistological stain of endothelial cells
smallestfree living organisms; cause walking pneumonia (M. pneumoniae); spread by aerosol droplets
Mycoplasma
colonies have fried egg appearance; special transfer; special media; EIA IHA; serological tests
C. trachomatis is most common sexually transmitted disease; causes sterility in females, trachoma, and lymphogranuloma venerum (LGV)--ulcers on genitalia, red skin,rectal bleeding; conjuctivitis and pneumoniae in newborns
Chlamydia
complex culturing, direct specimen examinations using EIA and DFA, nucleic acid probes