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25 Cards in this Set
- Front
- Back
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uses of Benzos
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anxiety
seizures (all partials and tonic clonic) insomnia induction of anesthesia (thiopental) |
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uses of Barbs
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anxiety
seizures (only stat epiliptecus and ecclampsia) delirium tremens night terrors sleep walking |
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Which Benzo or barb induces P450?
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barb
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Which Benzo or barb causes significant resp and cardio depression, and coma?
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Barb
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S/E's that barbs and benzos have in common:
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"STD"
sedation, tolerance, dependence |
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Which Benzos do we use for delirium tremens?
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Diazepam
Chlordiazepoxide |
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Which Benzos or barbs has less respiratory depression and coma?
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Benzos
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Barbs are contraindicated in...
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pts with porphyria
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What is porphyria?
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accumulation of heme precursors (porphorins)
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Rx for Barb o/d
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symptomatic mgmt (assist respiration and BP)
"barb needs bicarb" |
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Rx for Benzo o/d
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flumazenil
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flumazenil
MOA |
MOA: competetive inh at the benzo binding site on the GABA receptor
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What are the short-acting benzos?
5 things to know about the short acting benzos? |
"TOMA"
Triazolam Oxazepam Midazolam Alprazolam in comparison to longer acting benzos 1) rapid clearance 2) less drowsy 3) less falls 4) higher addictive potential 5) greater w/d |
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Which Barb can we use as an IV anesthetic?
How do anesthesiologists use it? |
Thiopental
uses in anesthesia: 1) induction of anesthesia 2) short surgical procedures |
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What Benzo can we use as an IV anesthetic?
How do anesthesiologists use it? |
Midazolam
uses in anesthesia: 1) endoscopy (with opiates and gaseous anesthetics) |
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Name the Benzos
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-zepam, -zolam, chlordiazepoxide
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Name the Barbs
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-barbital, thiopental
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What are the long-acting benzos?
5 things to know about them |
1) Chlordiazepoxide
2) Clorazepate 3) Diazepam 4) Flurazepam In comparison to shorter acting benzos: 1) slower clearance 2) more drowsy 3) more falls 4) less dependance 5) less w/d |
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Which Benzo has the
-longest half life? -shortest half life? |
longest: Fluorazepam
shortest: Alprazelam |
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Which Barbituate has the
-longest half life? -shortest half life? |
longest: Phenobarbital
shortest: Thiopental |
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Which barbituate is most street abused?
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Secobarbital
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Rx for Barbituate o/d
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1) HCO3
2) Doxapram *****has no "z" so its not a benzo 3)****intubate!!!!! |
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Doxapram
MOA: use: |
MOA: stimulates carotid rec--> stim medulla--> inc RR
use: Barbituate o/d |
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Whats the #1 use of barbituates?
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infantile epilipticus
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Clonazepam can be used for:
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1) Restless leg syndrome
2) absence seizures (DOC is ethozuximide) |
