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20 Cards in this Set
- Front
- Back
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3 classes of antianxiety drugs
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benzodiazapines
buspirone carbamates |
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class of sedatives used to treat insomnia
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hypnotics
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Benzodiazapines activate binding sites on this receptor. Effect?
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GABA-a.
dec neuron and muscle firing |
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Chronic use of benzos can lead to...
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tolerance and dependence
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T/F: shorter acting benzos have a higher potential for abuse
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True
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Benzo receptor antagonist used for benzo overdose or post surgery to reverse benzo effects
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Flumazenil (Mazicon)
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Nonbenzo not associated with sedation or dependence.
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Buspirone (BuSpar)
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BuSpar primary mechanism
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serotonin (1a) receptor agonist
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BuSpar is not used when?
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when you need a quick response. Takes up to 2 wks to work
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2 non-benzos used to treat insomnia
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Zolpidem (Ambien)
Zaleplon (Sonata) |
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2 types of endocrine hormones used to treat mood disorders
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Thyroid hormones
Sex hormones |
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Mood stabilizer used to treat bipolar disorder
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Levothyroxine (Synthroid, Levothroid) = synthetic T4
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used to augment antidepressants
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Liothyronine (Cytomel) = synthetic T3
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Hormones used to improve mood
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Estrogen (women), Testosterone (men), and other androgens
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Glucocorticoid receptor antagonist, possible antidepressant
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mifepristone (RU-486 )
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Blocks enzyme that breaks down ACh
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ACh-esterase inhibitors
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Effect of AChI's
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slows memory loss, possible improvement
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Original AChI with many GI side effects. No longer used
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tacrine
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3 newer AChI's with fewer side effects
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donepezil (Aricept)
rivastigmine (Exelon) galantamine (Reminyl) |
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Decrease autonomic hyperarousal associated with some psych conditions (anxiety disorders, opiate/sedative withdrawal)
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B-antagonist (blockers) - propanolol
Alpha-2-adrenergic receptor antagonists - clonidine |
