Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
16 Cards in this Set
- Front
- Back
|
in the news
|
-Mother’s childhood experiences may affect the brain function of her offspring
-15 days, environmental enrichment novel objects, elevated social interactions, exercise -enhances “learning and memory” in enriched mice in their future offspring through early adolescence -environmental enrichment mask defective LTP in the offspring of enriched -juvenile of animals with deficits in LTP implications: delay in the onset or even a reversal of neurodegenerative diseases “it would suggest that experiences your mother had during adolescence could influence your memory Auger thinks its epigenetic but paper says its not |
|
|
excitatory potential (EPSP)
|
-An excitatory depolarization of the postsynaptic membrane.
-Caused by the liberation of a neurotransmitter by the terminal. -Multiple EPSPs effects on voltage are combined, the sum of the individual EPSPs reaches the threshold for firing an action potential. |
|
|
IPSP
|
inhibitory postsynaptic potential (IPSP)
An inhibitory hyperpolarization of the postsynaptic membrane of a synapse. Inside becomes more negative |
|
|
neural integration
|
The process by which inhibitory and excitatory potentials summate and control the rate of firing of a neuron.
|
|
|
Drug effects
|
The changes a drug produces in an animal’s physiological processes and behavior
|
|
|
Effects of Meth
|
Increased attention
Decreased fatigue Increased activity Decreased appetite Euphoria and rush Increased respiration Hyperthermia |
|
|
Effects of Meth contd
|
Dependence
Addiction psychosis Paranoia Hallucinations Mood disturbances Repetitive motor activity Stroke Weight loss All other legions Teeth |
|
|
Brain effects of Meth
|
BRAIN
Causes a cascading release of norepinephrine, dopamine and serotonin. Can act as a dopaminergic and adrenergic reuptake inhibitor Can act monoamine oxidase inhibitor (MAOI). Euphoria |
|
|
Pharmacokinetics
|
What the body does to the drug
Absorption, Distribution, Metabolism and Excretion |
|
|
What dictates pharmacokinetics
|
route of administration
|
|
|
Biological activity
|
(amount of time active in order to have desired effect)
|
|
|
Dose-response curve
|
the magnitude of an effect of a drug as a function of the amount of drug administration.
|
|
|
Therapeutic index
|
is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxic effects
the toxic dose of a drug for 50% of the population, divided by the minimum effective dose for 50% of the population |
|
|
Tolerance
|
A decrease in the effectiveness of a drug that is administered repeatedly.
Heroin – drug users need to take more to have desired effect |
|
|
Sensitization
|
An increase in the effectiveness of a drug that is administered repeatedly.
Cocaine - repeated use; more and more likely to produce movement disorders |
|
|
Withdrawal symptom
|
The appearance of symptoms opposite to those produced by a drug when the drug is administered repeatedly and then suddenly no longer taken.
Tolerance Withdrawal symptoms are usually the opposite of drug Heroin – Euphoria withdrawal - Disphoira |
