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48 Cards in this Set

  • Front
  • Back
How many NREM stages are there?
4
What are the deepest stages of NREM sleep?
3 and 4
REM makes up ___ of sleep time
¼
REM sleep and dreaming are triggered by ___
the pons
What is acronym for sleep history? What does it stand for?
BEARS. Bedtime, excessive daytime sleepiness, awakenings, regularity and duration of sleep, snoring
What is determined in temporal lobe?
Auditory and olfactory. Visual assosications (processing of what goes on in occipital lobe)
What is parietal lobe responsible for?
visual attention. touch perception. Manipulation of objects
What is function of medulla?
Centers for cough, gag, swallow, and vomit. Cardiac Center. Respiratory Center.
What is function of pons?
Arousal. Assists in Controlling Autonomic Functions. Relays Sensory Information Between the Cerebrum and Cerebellum. Sleep
Damage to cerebello-pontine structures would result in impaired _____
coordination of movement and/or posture
Where is substancia nigra found?
Midbrain
What is function of thalamus?
It relays to the cerebral cortex information received from diverse brain regions– the 'last pit stop' for information going to cortex
What is role of hypothalmu (3)?
1) many regulating functions including the autonomic nervous system, emotions and behavior, body temperature, hunger, thirst, sleep-waking cycles 2) Controls the release of hormones under its control: growth, prolactin, thyroid, corticotropin, and gonadotropins 3) Regulation of sex hormones, blood pressure, body temperature, water balance, respiration, and food intake,
What is shaped like a seahorse?
Hippocampus
What is function of hippocampus?
Stores, processes and retrieves memories . Affects emotions. Main relay station that determines whether a new memory should go into long-term storage or be deleted after its short-term usefulness is over
What are functions of basal ganglia?
Controls voluntary movements and establishing postures. Controls voluntary limb movement, eye movement, and cognition.
Disorders of movement may be mediated through ___
basal ganglia
What is a neurotransmitter?
released by terminal buttons of neurons and detected by receptors in the membrane of another cell a short distance away.
What is a neuromodulator?
released in large amounts from the terminal buttons, but diffused throughout part of the brain, affecting many neurons
What is a hormone?
produced by endocrine glands, released into extracellular fluid and from there into the bloodstream. Stimulate cell receptors on membrane surface or deep within nuclei of cells, including neurons
What are pheromones?
chemicals released into the environment through sweat, urine, or secretions of special glands. Most receptors in nose of other animals, but may also be detected in skin or other organs
What is ALWAYS the first signaler on efferent pathways to the peripheral nervous system?
Acetlcholine
What is Made from the amino acid tyrosine?
Catacholamines
What are the catacholamines?
Dopamine, norepinephrine, epinephrine
What destroys catacholamines?
MOA
What is made from Tryptophan?
Serotonin
Serotonin is ___ in muscle pathways, ___ in sensory pathways
excitatory. inhibitory
Opoids, unlike other transmitters, _________
these are made in the cell body, put into vesicles, and transported all the way down the axon for release.
What is the Physiologic Component of anxiety and panic?
Excessive Autonomic Discharge
To treat panic-____
benzodiazepines
For chronic prevention of panic and anxiety_____
SSRI’s or Tricyclics
For systemic symptoms of panic and anxiety ____
Beta Blockers
The structural abnormalities believed to be linked to bipolar disorder are ____
amygdala, basal ganglia, and prefrontal cortex.
Unmedicated bipolar patients have ___ amygdalas
smaller
The extreme ‘mood swings’ in bipolar disorder have been strongly associated with ___
disruptions in circadian rhythms
Lithium blocks ___ enzyme
GSK3
If you have too much of __ your circadian cycles are all screwed up
GSK3
___ makes GSK3 enzyme
CLOCK gene
schitzophrenia is associated with ___
SNPs
what is Neuregulin?
A growth hormone releasing factor.Its absence may predispose to schizophrenia.
What genes might cause schizophrenia?
12 and 8
One theory says – schizophrenia caused by an overactive ___ system
dopamine
Many drugs for schizophrenia work by blocking ___ receptors
dopamine
As part of the reward pathway, ____ is manufactured in nerve cell bodies located within the ___ and is released in the ___.
Dopamine. ventral tegmental area (VTA). nucleus accumbens and the prefrontal cortex.
The motor functions of dopamine are linked to a separate pathway, with cell bodies in the ___
substantia nigra.
CT scans of schizophrenic patients feature ___
larger than normal lateral ventricles
Typical schizophrenia meds – block ___ receptors, help symptoms
dopamine. positive
Typical Atypicals schrizophrenia meds – block___; help with ___
serotonin and dopamine. Helps with pos and neg symptoms